Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Yuko, Matsushima"'
Autor:
Chihiro Otsubo, Ryo Otomo, Makoto Miyazaki, Yuko Matsushima-Hibiya, Takashi Kohno, Reika Iwakawa, Fumitaka Takeshita, Hirokazu Okayama, Hitoshi Ichikawa, Hideyuki Saya, Tohru Kiyono, Takahiro Ochiya, Fumio Tashiro, Hitoshi Nakagama, Jun Yokota, Masato Enari
Publikováno v:
Cell Reports, Vol 7, Iss 2, Pp 527-538 (2014)
Summary: In lung cancer progression, p53 mutations are more often observed in invasive tumors than in noninvasive tumors, suggesting that p53 is involved in tumor invasion and metastasis. To understand the nature of p53 function as a tumor suppressor
Externí odkaz:
https://doaj.org/article/e73b97deeab04def8cdc0bfcc1c5e983
Autor:
Takahiro Ochiya, Ryuichi Sakai, Naomi Abe, Arata Tomiyama, Koichi Ichimura, Ryo Otomo, Masato Enari, Makoto Miyazaki, Hitoshi Nakagama, Hidenobu Suzuki, Koichi Matsuda, Toshiki Watanabe, Ayana Nakajima, Yuko Matsushima-Hibiya
Publikováno v:
Cell Death Discovery, Vol 4, Iss 1, Pp 1-17 (2018)
Cell Death Discovery
Cell Death Discovery
Anaplastic lymphoma kinase (ALK) is an oncogenic receptor tyrosine kinase that is activated by gene amplification and mutation in neuroblastomas. ALK inhibitors can delay the progression of ALK-driven cancers, but are of limited use owing to ALK inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91b112faeed47dd51951f5d28b1320cb
https://doi.org/10.1038/s41420-018-0059-0
https://doi.org/10.1038/s41420-018-0059-0
Autor:
Katsumi Kobayashi, Hideki Serizawa, Mika Takahashi, Atsushi Ono, Hina Kato, Akihiko Hirose, Yuko Matsushima, Mutsuko Hirata-Koizumi, Mariko Matsumoto, Tomoko Kawamura
Publikováno v:
Fundamental Toxicological Sciences. 2:191-200
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e0b63c2077f7753e292ba26bc1365a9
https://doi.org/10.2131/fts.2.191
https://doi.org/10.2131/fts.2.191
Autor:
Fumio Tashiro, Masato Enari, Takahiro Ochiya, Fumitaka Takeshita, Reika Iwakawa, Makoto Miyazaki, Tohru Kiyono, Hitoshi Ichikawa, Jun Yokota, Ryo Otomo, Yuko Matsushima-Hibiya, Hitoshi Nakagama, Hideyuki Saya, Takashi Kohno, Chihiro Otsubo, Hirokazu Okayama
Publikováno v:
Cell Reports, Vol 7, Iss 2, Pp 527-538 (2014)
Summary: In lung cancer progression, p53 mutations are more often observed in invasive tumors than in noninvasive tumors, suggesting that p53 is involved in tumor invasion and metastasis. To understand the nature of p53 function as a tumor suppressor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d3ad36a4108b7b6a183be0d4e2745dc
https://doi.org/10.1016/j.celrep.2014.03.027
https://doi.org/10.1016/j.celrep.2014.03.027
Autor:
Hirofumi Arakawa, Yoichi Taya, Chihiro Otsubo, Yuko Matsushima-Hibiya, Masato Enari, Ryo Otomo, Hirokazu Ohata, Makoto Miyazaki, Takahiro Nagase, Hitoshi Nakagama, Jun Yokota
Publikováno v:
Molecular and Cellular Biology. 33:2447-2457
The p53 tumor suppressor protein is a transcription factor controlling various outcomes, such as growth arrest and apoptosis, through the regulation of different sets of target genes. The nuclear mitotic apparatus protein (NuMA) plays important roles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9878f045bea3ecf9828584c4c759b704
https://doi.org/10.1128/mcb.01221-12
https://doi.org/10.1128/mcb.01221-12
Autor:
Tsuyoshi Nakano, Yukari Totsuka, Hirokazu Fukuda, Masafumi Yamamoto, Azusa Takahashi-Nakaguchi, Haruyasu Kinashi, Takeji Takamura-Enya, Yuko Matsushima-Hibiya, Masaya Ono
Publikováno v:
Toxicon. 63:55-63
The Streptomyces coelicolor A3(2) genome encodes a possible secretion protein, SCO5461, that shares a 30% homology with the activity domains of two toxic ADP-ribosyltransferases, pierisins and mosquitocidal toxin. We found ADP-ribosylating activity f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf81e4a59323b2aeb7bc18889b8eccd4
https://doi.org/10.1016/j.toxicon.2012.11.019
https://doi.org/10.1016/j.toxicon.2012.11.019
Publikováno v:
Methods in Molecular Biology ISBN: 9781493969531
Ataxia-telangiectasia mutated (ATM) protein is a member of the phosphatidylinositol 3-phosphate kinase (PI3-K)-related protein kinase (PIKK) family and is implicated in the initiation of signaling pathways following DNA double strand breaks (DSBs) el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28aefe82bb03121dd6dc5e08197a8c8a
https://doi.org/10.1007/978-1-4939-6955-5_11
https://doi.org/10.1007/978-1-4939-6955-5_11
Autor:
Shuji Takiguchi, Yoshiyuki Fujiwara, Yuko Matsushima, Masaki Mori, Yuichiro Doki, Makoto Yamasaki
Publikováno v:
Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association). 72:658-662
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a5608651342dd23bb2230ef73832d30
https://doi.org/10.3919/jjsa.72.658
https://doi.org/10.3919/jjsa.72.658
Autor:
Tsuyoshi Nakano, Takashi Sugimura, Osamu Yata, Yasuko Matsumoto, Keiji Wakabayashi, Masafumi Yamamoto, Ken-Ichi Odagiri, Kotaro Koyama, Yuko Matsushima-Hibiya
Publikováno v:
Proceedings of the National Academy of Sciences. 105:2516-2520
Cabbage butterflies, Pieris rapae and Pieris brassicae , contain strong cytotoxic proteins, designated as pierisin-1 and -2, against cancer cell lines. These proteins exhibit DNA ADP-ribosylating activity. To determine the distribution of substances
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82be28be08088720780d3426d2cbf2e7
https://doi.org/10.1073/pnas.0712221105
https://doi.org/10.1073/pnas.0712221105
Autor:
Kikuo Iwabuchi, Yasuko Matsumoto, Tsuyoshi Nakano, Masafumi Yamamoto, Keiji Wakabayashi, Yuko Matsushima-Hibiya, Sugimura T
Publikováno v:
Proceedings of the Japan Academy. Series B, Physical and Biological Sciences
Crude extracts from larvae, pupae and adults of cabbage white butterflies, Pieris rapae and Pieris brassicae, and green-veined butterfly, Pieris napi, have an ability to induce apoptosis in the human cancer cell lines. As apoptosis inducing protein,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::560aae5c1dc0fd5a61b50e7b5e8f50f5
http://europepmc.org/articles/PMC3855205
http://europepmc.org/articles/PMC3855205