Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Yukiyasu Mariko"'
Autor:
Yukiyasu Mariko, Tomoyuki Ando, Takashi Tsuruo, Yasuhito Nosaka, Osamu Nakanishi, Katsutoshi Tsuchiya, Tsuneji Suzuki, Takashi Yamashita, Akiko Saito
Publikováno v:
Proceedings of the National Academy of Sciences. 96:4592-4597
Synthetic benzamide derivatives were investigated for their ability to inhibit histone deacetylase (HDA). In this study, one of the most active benzamide derivatives, MS-27-275, was examined with regard to its biological properties and antitumor effi
Autor:
Akiko Saito, Osamu Nakanishi, Tomoyuki Ando, Nobuyuki Fukazawa, Katsutoshi Tsuchiya, Yukiyasu Mariko, Tsuneji Suzuki, Takashi Yamashita
Publikováno v:
Journal of Medicinal Chemistry. 42:3001-3003
Newly synthesized benzamide derivatives were evaluated for their inhibitory activity against histone deacetylase. The structure of these derivatives was unrelated to the known inhibitors, and IC(50) values of the active compounds were in the range of
Autor:
Hideaki Tojo, Hidetoshi Mori, Chikashi Tachi, Satomi S. Tanaka, Hiroshi Sato, Junko Ishijima, Yukiyasu Mariko, Motoharu Seiki, Sumie Tachi, Keitaro Yamanouchi
Publikováno v:
Zoological science. 14(1)
Membrane type matrix metalloproteinase (MT-MMP), which possesses a C-terminal transmembrane domain, is expressed on the cell membrane (Sato et al., 1994, Nature 370: 61-65). It was suspected, therefore, that the expression of MT-MMPs might be regulat