Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Yukiya Ohnishi"'
Publikováno v:
Biological and Pharmaceutical Bulletin. 45:1609-1615
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0caafac7d8719f5a98a2ba3f3feb0ca1
https://doi.org/10.1248/bpb.b22-00131
https://doi.org/10.1248/bpb.b22-00131
Autor:
Hiroki Tanaka, Daisuke Tsuji, Ryosuke Watanabe, Yukiya Ohnishi, Shindai Kitaguchi, Ryuto Nakae, Hiromi Teramoto, Jun Tsukimoto, Yuto Horii, Kohji Itoh
Publikováno v:
Journal of Inherited Metabolic Disease. 45:1191-1202
Lysosomal storage disorders (LSDs) are inherited metabolic diseases caused by genetic defects in lysosomal enzymes or related factors. LSDs are associated with excessive accumulation of natural substrates in lysosomes leading to central nervous syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6ba4f2396644c6f080f57a44c2a20a4
https://doi.org/10.1002/jimd.12558
https://doi.org/10.1002/jimd.12558
Publikováno v:
Biologicalpharmaceutical bulletin. 45(11)
Autophagy is a highly conserved intracellular degrading system and its dysfunction is considered related to the cause of neurodegenerative disorders. A previous study showed that the inhibition of endocytosis transport attenuates soluble N-ethylmalei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ca7a6aa811ce0f41144715e21db4149d
https://pubmed.ncbi.nlm.nih.gov/36328496
https://pubmed.ncbi.nlm.nih.gov/36328496
Autor:
Kohji Itoh, Daisuke Tsuji, Katsuhito Asai, Shin-ichi Muramatsu, Yukiya Ohnishi, Ryosuke Watanabe
Publikováno v:
Molecular Genetics and Metabolism. 126:S78
Tay-Sachs disease (TSD) and Sandhoff disease (SD) are autosomal recessive GM2 gangliosidoses, caused by the gene mutations of HEXA and HEXB encoding the α and β-subunits of lysosomal β-hexosaminidase (Hex), respectively. These incurable diseases a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06317d1ba0679c91f0c3ee757af2b027
https://doi.org/10.1016/j.ymgme.2018.12.190
https://doi.org/10.1016/j.ymgme.2018.12.190