Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Yukitsugu Ono"'
Autor:
Shinichi Fujita, Seiji Ohno, Seiji Niwa, Hajime Koganei, Yuki Saitou, Seinosuke Iwata, Akira Takahara, Tomoko Takeda, Tomoyuki Onishi, Takashi Yamamoto, Munetaka Tokumasu, Chika Nakanishi, Morikazu Kito, Akira Nakajo, Yukitsugu Ono, Masataka Shoji, Yoko Masuzawa
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:4813-4816
In order to find an injectable and selective N-type calcium channel blocker, we have performed the structure-activity relationship (SAR) study on the 2-, 5-, and 6-position of 1,4-dihydropyridine-3-carboxylate derivative APJ2708 (2), which is a deriv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b86b1d751e45f33b333b46f09d74e181
https://doi.org/10.1016/j.bmcl.2008.07.096
https://doi.org/10.1016/j.bmcl.2008.07.096
Autor:
Akira Takahara, Seiji Ohno, Hiroyuki Matsueda, Hisayuki Uneyama, Masataka Shoji, Shinichi Fujita, Tomoko Takeda, Seinosuke Iwata, Tomoyuki Onishi, Seiji Niwa, Morikazu Kito, Hajime Koganei, Yuki Saitou, Yukitsugu Ono, Takashi Yamamoto
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:798-802
Cilnidipine is a 1,4-dihydropyridine derived L/N-type calcium channel dual blocker possessing neuroprotective and analgesic effects which are related to its N-type calcium channel inhibitory activity. In order to find specific N-type calcium channel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e409c773f0b8a9e6feef5d47c8042074
https://doi.org/10.1016/j.bmcl.2005.11.021
https://doi.org/10.1016/j.bmcl.2005.11.021
Autor:
Kazuo Hotate, Yukitsugu Ono
Publikováno v:
TRENDS IN THE SCIENCES. 20:12_40-12_45
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a37afae114b1e43d5d0f6f0df45b9dc8
https://doi.org/10.5363/tits.20.12_40
https://doi.org/10.5363/tits.20.12_40
Autor:
Tomoko Takeda, Satoshi Iwayama, Hiroshi Yamamoto, Seinosuke Iwata, Shinichi Fujita, Yukitsugu Ono, Masataka Shoji, Morikazu Kito, Akira Takahara, Seiji Niwa, Hajime Koganei, Takashi Yamamoto, Yuki Saitou
Publikováno v:
Bioorganicmedicinal chemistry. 14(15)
Antiallergic drug cyproheptadine (Cyp) is known to have inhibitory activities for L-type calcium channels in addition to histamine and serotonin receptors. Since we found that Cyp had an inhibitory activity against N-type calcium channel, Cyp was opt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15fb0ee32d5ed68367bdf3d63489ad4c
https://pubmed.ncbi.nlm.nih.gov/16616501
https://pubmed.ncbi.nlm.nih.gov/16616501
Autor:
Satoshi Iwayama, Keiko Moki, Shinichi Fujita, Hiroshi Yamamoto, Yukitsugu Ono, Hajime Koganei, Akira Takahara
Publikováno v:
Hypertension research : official journal of the Japanese Society of Hypertension. 26(9)
Although the anti-sympathetic mechanisms of the antihypertensive drug cilnidipine have been analyzed in neuronal cells derived from rodents, there is little information regarding the effects of cilnidipine in human neuronal cells. We investigated the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eac4ec829a247651162192dd0c46a315
https://pubmed.ncbi.nlm.nih.gov/14620931
https://pubmed.ncbi.nlm.nih.gov/14620931
Autor:
Masakazu Akahori, Tadashi Noguchi, Asako Takenaka, Yoshiaki Ito, Shinichiro Takahashi, Taku Nedachi, Yukitsugu Ono, Tomoko Koide, Fumihiko Hakuno
Publikováno v:
Endocrine journal. 45(2)
In FRTL-5 cells, we and others have shown that TSH and insulin-like growth factor-I (IGF-I) stimulate DNA synthesis synergistically. The present study was undertaken to determine whether interaction between TSH and IGF-I also affects protein synthesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd373ac534082a007bd5fa7806d67159
https://pubmed.ncbi.nlm.nih.gov/9700468
https://pubmed.ncbi.nlm.nih.gov/9700468
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 59:1358-1359
An Enterococcus faecalis plasmid, pAM373, has a high frequency of transfer in a liquid medium when induced by a recipient-produced sex pheromone, cAM373. The sex pheromone inhibitor against cAM373, termed iAM373, was isolated from a culture supernata
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0eff82cb4af2c213f7cef7ee3bbe711
https://doi.org/10.1271/bbb.59.1358
https://doi.org/10.1271/bbb.59.1358