Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Yukiteru Mimura"'
Autor:
Tomoko Tsuchiya, Yutaka Tomoda, Motoo Yamasaki, Yukiteru Mimura, Hisao Nemoto, Toshiyuki Suzawa, Atsushi Ishihara, Ayato Katagiri, Masahiro Yamauchi, Masaaki Kamiya
Publikováno v:
Journal of Biomaterials Science, Polymer Edition. 23:2055-2068
Liposomes are recognized as potentially useful drug carriers but many problems preclude practical medical application. Liposomes bind with serum proteins (opsonization) and are captured by the reticuloendothelial system cells in the liver and spleen,
Autor:
Ayato Katagiri, Motoo Yamasaki, Hisao Nemoto, Atsushi Ishihara, Takaaki Araki, Yutaka Tomoda, Masaki Kamiya, Tsuyoshi Matsushita, Hatsuhiko Hattori, Yukiteru Mimura
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:4724-4727
Synthesis of a symmetrically branched diglycerol (BGL002, involving one iminodiacetic residue) as a G2 dendron, and the tetradecaglycerol (BGL014, involving one iminodiacetic residue) as a G4 dendron, is described. Several members of the BGL family o
Autor:
Atsushi Ishihara, Hiroko Kusano, Masaki Kawano, Masaaki Kamiya, Yukiteru Mimura, Ayato Katagiri, Masashi Nakakura, Motoo Yamasaki, Hisao Nemoto, Masahiro Yamauchi, Toshiyuki Suzawa
Publikováno v:
International Journal of Pharmaceutics. 391:237-243
We examined the effect on drug delivery of liposomes with surfaces that were modified with branched oligoglycerols (BGLs) and explored possible formulation advantages to increase drug exposure. BGL012 is a branched oligoglycerol derivative with a cas
Autor:
Masaji Kasai, Masahiko Kinugawa, Yoshiaki Masuda, Takehiro Ogasa,† and, Chikara Murakata, Yukiteru Mimura
Publikováno v:
Organic Process Research & Development. 3:131-134
A facile and large-scale preparation process of an antitumor agent KT6587 (2), derived from an indolocarbazole alkaloid K252a (1), has been developed. The new synthetic process requires four steps: (i) selective N-silylation of the amide group of 1 w
Autor:
Yukiteru Mimura, Shinji Tomioka, Toru Sugaya, Takashi Mimura, Masanori Ikuta, Nobuyuki Kato, Masaji Fujisawa-shi Kasai
Publikováno v:
Synthesis. 1994:73-76
A 6H-pyrazolo[4,5,1-de]acridin-6-one derivative, a useful intermediate of antitumor agents, was prepared by a facile synthetic route from 2-bromobenzoic acid and 6-nitroindazole involving a halogenocopper(I)-catalyzed Ullmann coupling reaction and Fr
Autor:
Toru Sugaya, Yukiteru Mimura, Masaji Kasai, Takashi Mimura, Masanori Ikuta, Nobuyuki Kato, Shinji Tomioka
Publikováno v:
ChemInform. 25
Autor:
Masahiko Kinugawa, Chikara Murakata, Masaji Kasai, Yoshiaki Masuda, Takehiro Ogasa, Yukiteru Mimura
Publikováno v:
ChemInform. 30
Autor:
Makoto Morimoto, Masami Okabe, Ikuo Matsukuma, Yasushi Shida, Shun-Ichi Ikeda, Toru Sugaya, Y. Osawa, Tadashi Ashizawa, Yukiteru Mimura, Shiro Akinaga
Publikováno v:
Journal of medicinal chemistry. 37(7)
The 7-substituted 6H-pyrazolo[4,5,1-de]acridin-6-ones with (aminoalkyl)amino and/or (hydroxy-alkyl)amino groups in the side chains were synthesized by bromination using N-bromosuccinimide and the subsequent reaction with amines from the 7-substituted