Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Yukishige Dr Nishino"'
Autor:
Tsuyuki Nishino, Kanako Ishibashi, Hiroshi Yamanouchi, Christian Hirtreiter, Yukishige Dr Nishino
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 114:152-160
The effects of ZK 191703 (ZK), a pure antiestrogen, on ovulation, follicle development and peripheral hormone levels were investigated in rats with 4-day estrus cycle and gonadotropin-primed immature rats in comparison to tamoxifen (TAM)-treatment. I
Autor:
J. Donath, Yukishige Dr Nishino
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 66:247-254
The present study was undertaken to compare the effects of the pure antiestrogen ZM 182780 (ZM) and the partial agonist tamoxifen (TAM) on ovulation and peripheral hormone levels in the rat. Adult female rats were treated with ZM (5 mg/kg/d) or TAM (
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 63:309-316
Measurements performed using cell lines or animal tissues have shown that the progesterone receptor (PR) can be induced by estrogens. By use of immunohistochemistry we studied the effects of estrogens on the PR levels in the individual cell types of
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 62:107-118
The present study was undertaken to investigate intraovarian mechanism(s) for the antiovulatory effect of Onapristone (ON), because antiprogestins possessing the same antiprogestational activity and inhibiting the preovulatory LH surge to the same ex
Publikováno v:
The Breast. 5:224-228
This paper examines the potential of progesterone antagonists for treating hormone dependent breast cancer, as judged from experimental studies. The original lead compound, Ru (38)486 (Mifepristone), was intended originally to be an antiglucocorticoi
Autor:
Klaus Nickisch, Henry Laurent, Ekkehard Schillinger, Yukishige Dr Nishino, Walter Dr Elger, Dieter Bittler, Rudolf Prof. Wiechert, Sybille Dr. Beier, Losert Wolfgang
Publikováno v:
ChemInform. 22
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 41:841-845
The present study was undertaken to investigate our recent finding that the peripheral levels of prolactin are elevated after the treatment of intact tumor-bearing rats with antiprogestins, like ONAPRISTONE (ON) and MIFEPRISTONE (MI). In ovariectomiz
Publikováno v:
Journal of Endocrinology. 130:409-414
The oestrogenic and antioestrogenic effects of a new non-steroidal compound ZK 119010(2-(4-hydroxyphenyl)-3-methyl-1-[6-(1-pyrrolidinyl)-hexyl]-indol-5-ol) were evaluated and compared with those of tamoxifen and ICI 164384. In immature mice, ZK 11901
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 116(3-5)
The present study was undertaken to investigate the antitumor effect of a combination of the antiestrogen tamoxifen (TAM) and either the antiprogestin onapristone (ON) or the progestogen megestrol acetate (MEG) in experimental mammary tumor models. R
Publikováno v:
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft. 182(2)
Summary These studies analyze the regulation of progesterone receptors (PRs) in central and peripheral tissues with the aim of further understanding mechanistically the inhibition of ovulation by progesterone antagonists (PA). Therefore, it was of in