Zobrazeno 1 - 10
of 249
pro vyhledávání: '"Yukio Takano"'
Autor:
Tomoharu Masuda, Yasutoshi Hirabara, Yusuke Nakamura, Akiko Chishaki, Mai Tsuruhisa, Masayuki Miyakawa, Kenji Honda, Ryo Saito, Hirotaka Sakamoto, Mitsuhiro Kawata, Yukio Takano
Publikováno v:
Journal of Pharmacological Sciences, Vol 112, Iss 4, Pp 482-486 (2010)
We examined the role of aldosterone-sensitive neurons in the nucleus tractus solitarius (NTS) in the arterial baroreceptor reflex (baroreflex) function. Baroreflex sensitivity was induced by phenylephrine in high sodium–loaded rats and was signific
Externí odkaz:
https://doaj.org/article/5cec4f249f25433fb3d29b1756f4bfbf
Autor:
Kenji Honda, Yukio Takano
Publikováno v:
Journal of Pharmacological Sciences, Vol 109, Iss 1, Pp 38-43 (2009)
Arginine vasopressin (AVP) receptors have been classified into V1a, V1b, and V2 subtypes. Recent studies have demonstrated the involvement of AVP in anti-nociception and in morphine-induced anti-nociception. However, the roles of individual AVP-recep
Externí odkaz:
https://doaj.org/article/a2d2183293454fc5ad70c5513e0a24af
Autor:
Kenji Honda, Keigo Horikawa, Suguru Ando, Kohei Koga, Satoshi Kawata, Keisuke Migita, Yukio Takano
Publikováno v:
Journal of Pharmacological Sciences, Vol 108, Iss 4, Pp 472-479 (2008)
The present study was undertaken to clarify how spinal muscarinic receptors are involved in the antinociceptive effects in thermal stimulation. Intrathecal (i.t.) injection of the muscarinic agonist McN-A-343 inhibited the tail-flick response to noxi
Externí odkaz:
https://doaj.org/article/d893fb40265545a5a3a4b5d10a7d614b
Autor:
Yasutoshi Hirabara, Mina Araki, Mio Fukuda, Shiori Katafuchi, Kenji Honda, Ryo Saito, Yukio Takano
Publikováno v:
Journal of Pharmacological Sciences, Vol 104, Iss 4, Pp 402-405 (2007)
We examined endothelium-derived hyperpolarizing factor (EDHF)-mediated relaxation of mesenteric arteries in high-sodium loaded streptozotocin (STZ)-induced diabetic rats. The study shows that acetylcholine (ACh)-induced, EDHF-mediated relaxation is r
Externí odkaz:
https://doaj.org/article/96a99f2e7d0c497f94dcf65cfb233e8b
Publikováno v:
Journal of Pharmacological Sciences, Vol 91, Iss 2, Pp 87-94 (2003)
The emetic response is primarily a protective reflex occurring in a wide variety of vertebrates in response to the ingestion of toxic compounds. The role of the nuclei in the brainstem, including the area postrema, nucleus tractus solitarius, the dor
Externí odkaz:
https://doaj.org/article/0ec6598d7080417a92acbbf761032b5e
Autor:
Yuko Tomonoh, Masanobu Deshimaru, Kimi Araki, Yasuhiro Miyazaki, Tomoko Arasaki, Yasuyoshi Tanaka, Haruna Kitamura, Fumiaki Mori, Koichi Wakabayashi, Sayaka Yamashita, Ryo Saito, Masayuki Itoh, Taku Uchida, Junko Yamada, Keisuke Migita, Shinya Ueno, Hiroki Kitaura, Akiyoshi Kakita, Christoph Lossin, Yukio Takano, Shinichi Hirose
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88549 (2014)
Knock-in mouse models have contributed tremendously to our understanding of human disorders. However, generation of knock-in animals requires a significant investment of time and effort. We addressed this problem by developing a novel knock-in system
Externí odkaz:
https://doaj.org/article/39c916144d874070b91a1e1527fbd817
Autor:
Gozoh Tsujimoto, Michio Nakaya, Akito Tanoue, Kenji Honda, Akira Hirasawa, Yukio Takano, Katsushi Shibata, Sachi Nagaoka-Uozumi, Ikuo Kimura, Hitoshi Kurose, Taka-aki Koshimizu, Kentarou Ushijima, Akio Fujimura, Atsuhiko Ichimura, Nobuya Sakai
Publikováno v:
Nature neuroscience. 21(6)
Chronic morphine exposure upregulates adenylate cyclase signaling and reduces analgesic efficacy, a condition known as opioid tolerance. Nonopioid neurotransmitters can enhance morphine tolerance, but the mechanism for this is poorly understood. We s
Autor:
Yukio Takano, Kenji Honda, Tomoharu Masuda, Akiko Chishaki, Mitsuhiro Kawata, Ryo Saito, Hirotaka Sakamoto, Yusuke Nakamura, Mai Tsuruhisa, Masayuki Miyakawa, Yasutoshi Hirabara
Publikováno v:
Journal of Pharmacological Sciences, Vol 112, Iss 4, Pp 482-486 (2010)
We examined the role of aldosterone-sensitive neurons in the nucleus tractus solitarius (NTS) in the arterial baroreceptor reflex (baroreflex) function. Baroreflex sensitivity was induced by phenylephrine in high sodium–loaded rats and was signific
Autor:
Keisuke Migita, Satoshi Kawata, Kenji Honda, Kohei Koga, Yukio Takano, Suguru Ando, Keigo Horikawa
Publikováno v:
Journal of Pharmacological Sciences, Vol 108, Iss 4, Pp 472-479 (2008)
The present study was undertaken to clarify how spinal muscarinic receptors are involved in the antinociceptive effects in thermal stimulation. Intrathecal (i.t.) injection of the muscarinic agonist McN-A-343 inhibited the tail-flick response to noxi
Autor:
Kenji Honda, Yukio Takano
Publikováno v:
Folia Pharmacologica Japonica. 130:39-44