Immune checkpoint inhibitor-induced anti-striational antibodies in myasthenia gravis and myositis: a case report

Autor: Yukio Sugiyama, Yoshiki Esa, Daisuke Takahashi, Akihiro Watanabe, Shigeaki Suzuki, Junya Kobayashi

Publikováno v: Rinsho Shinkeigaku. 61:630-634

A 78-year-old man was treated with ipilimumab and nivolumab for advanced renal cell carcinoma with liver and lymph node metastasis. He developed diplopia, ptosis, dysphagia, and weakness of the limbs and neck, 1 month after treatment. Serum creatine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06e315cb73922ddec37f5474abf864f6
https://doi.org/10.5692/clinicalneurol.cn-001604

Dietary salt promotes neurovascular and cognitive dysfunction through a gut-initiated TH17 response

Autor: Lidia Garcia-Bonilla, Michelle Murphy, Giuseppe Faraco, Gang Wang, Kenzo Koizumi, Joseph Anrather, Henning U. Voss, David Brea, Monica M Santisteban, Haejoo Chang, Izaskun Buendia, Yukio Sugiyama, Steven G. Segarra, Gianfranco Racchumi, Costantino Iadecola

Publikováno v: Nature Neuroscience. 21:240-249

A diet rich in salt is linked to an increased risk of cerebrovascular diseases and dementia, but it remains unclear how dietary salt harms the brain. We report that, in mice, excess dietary salt suppresses resting cerebral blood flow and endothelial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9852778fa43b8bb70b67ce5abc71d7e
https://doi.org/10.1038/s41593-017-0059-z

Vertebral artery dissection diagnosed by T1‐weighted volume isotropic turbo spin‐echo acquisition

Autor: Yukio Sugiyama, Akihiro Watanabe, Yoshiki Esa, Daisuke Takahashi, Junya Kobayashi, Atsushi Ogawa

Publikováno v: Neurology and Clinical Neuroscience. 9:148-149

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bd044f28d8836855853bad6b9e1c616d
https://doi.org/10.1111/ncn3.12447

Abstract WMP64: Utility of Left Atrial Abnormality on Admission Electrocardiography in Acute Ischemic Stroke

Autor: Junya Kobayashi, Kotaro Watanabe, Yukio Sugiyama, Nobuyuki Ohara, Daisuke Takahashi

Publikováno v: Stroke. 48

Introduction and Hypothesis: Clinical categorization of ischemic stroke is very important to select the antithrombotic therapy for preventing the recurrent stokes. However, about 25% of ischemic stroke is the stroke for undetermined cause, termed as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0d9080aed8e871c5876704d48985351b
https://doi.org/10.1161/str.48.suppl_1.wmp64

Perivascular macrophages mediate the neurovascular and cognitive dysfunction associated with hypertension

Autor: Nico van Rooijen, Costantino Iadecola, Giuseppe Faraco, Diane A. Lane, Monica M Santisteban, Michelle Murphy, Gianfranco Racchumi, Joseph Anrather, Haejoo Chang, Lidia Garcia-Bonilla, Yukio Sugiyama

Publikováno v: Faraco, G, Sugiyama, Y, Lane, D, Garcia-Bonilla, L, Chang, H, Santisteban, M M, Racchumi, G, Murphy, M, Van Rooijen, N, Anrather, J & Iadecola, C 2016, ' Perivascular macrophages mediate the neurovascular and cognitive dysfunction associated with hypertension ', Journal of Clinical Investigation, vol. 126, no. 12, pp. 4674-4689 . https://doi.org/10.1172/JCI86950
Journal of Clinical Investigation, 126(12), 4674-4689. The American Society for Clinical Investigation

Hypertension is a leading risk factor for dementia, but the mechanisms underlying its damaging effects on the brain are poorly understood. Due to a lack of energy reserves, the brain relies on continuous delivery of blood flow to its active regions i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d69c00ec3e810987ecabeffef6787745
https://research.vumc.nl/en/publications/5b6efae9-4d9c-467c-bc03-815b1fbd0b56