Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Yukio Oniyama"'
Autor:
Sono Sawada, Kazuhiro Kajiyama, Haruka Shida, Ryota Kimura, Yuki Nakazato, Toyotaka Iguchi, Yukio Oniyama, Chieko Ishiguro, Yoshiaki Uyama
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 2, Pp 206-215 (2023)
Abstract In the present study, we aimed to investigate the association between urate‐lowering drugs and cardiovascular events, primarily focusing on the risk of febuxostat and topiroxostat when compared with allopurinol in Japan. We conducted an ob
Externí odkaz:
https://doaj.org/article/4fef8c49a4ba432e89f6551a1a6577a5
Autor:
Haruka Shida, Kazuhiro Kajiyama, Sono Sawada, Chieko Ishiguro, Mikiko Kubo, Ryota Kimura, Mai Hirano, Noriyuki Komiyama, Toyotaka Iguchi, Yukio Oniyama, Yoshiaki Uyama
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
The Pharmaceuticals and Medical Devices Agency (PMDA) has conducted many pharmacoepidemiological studies for postmarketing drug safety assessments based on real-world data from medical information databases. One of these databases is the National Dat
Externí odkaz:
https://doaj.org/article/ab7cb8b8c86647c585e7d163de6b27d1
Autor:
Sono Sawada, Kazuhiro Kajiyama, Haruka Shida, Ryota Kimura, Yuki Nakazato, Toyotaka Iguchi, Yukio Oniyama, Chieko Ishiguro, Yoshiaki Uyama
Publikováno v:
Clinical and Translational Science. 16:206-215
In the present study, we aimed to investigate the association between urate-lowering drugs and cardiovascular events, primarily focusing on the risk of febuxostat and topiroxostat when compared with allopurinol in Japan. We conducted an observational
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e26e5518285eaf1862c14ce029b6c691
https://doi.org/10.1111/cts.13439
https://doi.org/10.1111/cts.13439
Autor:
Yoshiaki Uyama, Yukio Oniyama, Yuki Kubota, Chieko Ishiguro, Natsumi Kinoshita, Toyotaka Iguchi, Takashi Ando, Kazuhiro Kajiyama
Publikováno v:
Clinical Pharmacology and Therapeutics
Although several spontaneous case reports on the occurrence of thrombocytopenia in patients treated with human granulocyte colony-stimulating factor (G-CSF) preparations have been accumulated, its actual causality is still unclear. To investigate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12d059c71327f6e62c928a9e099be723
http://europepmc.org/articles/PMC8359991
http://europepmc.org/articles/PMC8359991
Autor:
Yukio Oniyama, Sono Sawada, Yoshiaki Uyama, Noriyuki Komiyama, Mai Hirano, Takashi Ando, Toyotaka Iguchi, Chieko Ishiguro
Publikováno v:
Therapeutic Innovation & Regulatory Science
Background Previous studies suggested that direct-acting antivirals (DAAs) against hepatitis C increased the blood coagulability of patients on warfarin. This study aims to descriptively investigate the effects of DAAs on the blood coagulability and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27a8e3c1f5f62ebcd39867e362eb24d5
https://doi.org/10.1007/s43441-020-00247-8
https://doi.org/10.1007/s43441-020-00247-8
Publikováno v:
Clinical pharmacology and therapeutics. 102(2)
The Japanese Postmarketing Relief System provides for compensation to patients with adverse reactions, based on the acknowledgment that unpredicted adverse events occur inevitably once a drug is marketed. The system also provides new knowledge about
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86e36c46457edddb8eb16c647682ab71
https://pubmed.ncbi.nlm.nih.gov/27737512
https://pubmed.ncbi.nlm.nih.gov/27737512
Autor:
Hirofumi Komiya, Yukio Oniyama, Yoshinori Tominaga, Yoshiki Matsuoka, Yoshimitsu Uchimura, Akira Hosomi, Shinya Kohra, Michiyo Hirayama
Publikováno v:
Journal of Heterocyclic Chemistry. 27:647-660
Polarized ethylenes having both electron-donating (an amino or a methylthio group) and electron-accepting (cyano, carbamoyl, methyl ester) groups on the adjacent two olefinic carbon atoms were prepared by the condensation of S-alkylthioamidinium salt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48a77e0e04d0dda325208bef58a173fc
https://doi.org/10.1002/jhet.5570270332
https://doi.org/10.1002/jhet.5570270332
Autor:
Yukio, Oniyama, Tamaki, Fushimi
Publikováno v:
Nihon rinsho. Japanese journal of clinical medicine. 65
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9092ddae61ac70f7cd28edf3ddf5629f
https://pubmed.ncbi.nlm.nih.gov/18074512
https://pubmed.ncbi.nlm.nih.gov/18074512
Autor:
Akira Hosomi, Shinya Kohra, Yoshinori Tominaga, M. Hirayama, Y. Uchimura, Yoshiki Matsuoka, Yukio Oniyama, H. Komiya
Publikováno v:
ChemInform. 21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d75bbf3e5339f210a7dd5816821e1523
https://doi.org/10.1002/chin.199037216
https://doi.org/10.1002/chin.199037216
Publikováno v:
Chemical and Pharmaceutical Bulletin. 33:3038-3041
The benzannalated cycl [3. 2. 2] azine, benzo [g] cycl [3. 2. 2] azine (2), was synthesized from 2-methylthiopyrrolo [2, 1-a] isoquinoline (5) and dimethyl acetylenedicarboxylate. The key intermediate (5) for the synthesis of 2 was prepared using the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5deb12130c3309095c08e75ab74a72c7
https://doi.org/10.1248/cpb.33.3038
https://doi.org/10.1248/cpb.33.3038