Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Yukio Imamura"'
Autor:
Yukio Imamura, Hisatake Matsumoto, Jun Imamura, Naoya Matsumoto, Kazuma Yamakawa, Nao Yoshikawa, Yuki Murakami, Satoko Mitani, Junichiro Nakagawa, Tomoki Yamada, Hiroshi Ogura, Jun Oda, Takeshi Shimazu
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Septic encephalopathy (SE) is characterized by symptoms such as coma, delirium, and cognitive dysfunction, and effective therapeutic interventions for SE remain elusive. In this study, we aimed to investigate the potential alleviating effects of vaga
Externí odkaz:
https://doaj.org/article/83e0fcea82834f48b644ea51bef2082f
Autor:
Yukio Imamura, Ayami Okuzumi, Saki Yoshinaga, Akiko Hiyama, Yoshiaki Furukawa, Tomohiro Miyasaka, Nobutaka Hattori, Nobuyuki Nukina
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Quantum dot-labelling of preformed α-synuclein fibrils enables visualization of pharmacological effects on fibril seed spreading.
Externí odkaz:
https://doaj.org/article/8d68a86a10f8449ea5fa372c41074d69
Autor:
Yuki Murakami, Yukio Imamura, Yoshiyuki Kasahara, Chihiro Yoshida, Yuta Momono, Ke Fang, Daisuke Sakai, Yukuo Konishi, Toshimasa Nishiyama
Publikováno v:
Cells, Vol 12, Iss 7, p 1087 (2023)
Several studies show that genetic and environmental factors contribute to the onset and progression of neurodevelopmental disorders. Maternal immune activation (MIA) during gestation is considered one of the major environmental factors driving this p
Externí odkaz:
https://doaj.org/article/594461f2a43e4d3a955ec48bb3c46942
Autor:
Hiroshi Ito, Sanae Hosomi, Yoshihisa Koyama, Hisatake Matsumoto, Yukio Imamura, Hiroshi Ogura, Jun Oda
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Sepsis is defined as a life-threatening multi-organ dysfunction triggered by an uncontrolled host response to infectious disease. Systemic inflammation elicited by sepsis can cause acute cerebral dysfunction, characterized by delirium, coma, and cogn
Externí odkaz:
https://doaj.org/article/8d75334cfc0a45548108da86ec55744d
Autor:
Kazuma Yamakawa, Naoya Matsumoto, Yukio Imamura, Takashi Muroya, Tomoki Yamada, Junichiro Nakagawa, Junya Shimazaki, Hiroshi Ogura, Yasuyuki Kuwagata, Takeshi Shimazu
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56728 (2013)
This study was performed to gain insights into novel therapeutic approaches for the treatment of heatstroke. The central nervous system regulates peripheral immune responses via the vagus nerve, the primary neural component of the cholinergic anti-in
Externí odkaz:
https://doaj.org/article/fdc3ead02b244298bc0d8421a3d4f9a1
Publikováno v:
Mediators of Inflammation, Vol 2013 (2013)
Indoleamine 2,3-dioxygenase 1 (IDO1), the L-tryptophan-degrading enzyme, plays a key role in the immunomodulatory effects on several types of immune cells. Originally known for its regulatory function during pregnancy and chronic inflammation in tumo
Externí odkaz:
https://doaj.org/article/0f3b594f78ee44f18ab3f45920e06982
Autor:
Yukio Imamura, Sayumi Yamada, Setsuko Tsuboi, Yuko Nakane, Yoshikazu Tsukasaki, Akihito Komatsuzaki, Takashi Jin
Publikováno v:
Molecules, Vol 21, Iss 8, p 1080 (2016)
Near-infrared (NIR) fluorescent imaging is a powerful tool for the non-invasive visualization of the inner structure of living organisms. Recently, NIR fluorescence imaging at 1000–1400 nm (second optical window) has been shown to offer better spat
Externí odkaz:
https://doaj.org/article/a9cfa69c09214c5bbda584f2f6eab931
Autor:
Tomoyuki Yamanaka, Akiko Hiyama, Yukio Imamura, Nobuyuki Nukina, Haruko Miyazaki, Junya Kasahara
Publikováno v:
Neuroscience Research. 170:341-349
The pathological form of a-synuclein (a-syn) is transmitted through neural circuits in the brains of Parkinson disease (PD) patients and amplifies misfolded a-syn, further forming intracellular deposits. However, the details of a-syn pre-formed fibri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db56cb18f863631357afc5aa3aa6d7b
https://doi.org/10.1016/j.neures.2020.11.009
https://doi.org/10.1016/j.neures.2020.11.009
Publikováno v:
Neuroscience research. 180
Amyloid fibril deposits are a main source of pathology in neurodegenerative diseases. Normal proteins such as tau, alpha-synuclein, TDP-43 and others could form specific conformational fibrils called amyloid, which deposited in the brains of neurodeg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f61bd6e6fefe341e9bbf8813e82535
https://pubmed.ncbi.nlm.nih.gov/35283247
https://pubmed.ncbi.nlm.nih.gov/35283247
Autor:
Yuta Momono, Toshimasa Nishiyama, Daisuke Sakai, Ke Fang, Yukio Imamura, Yukuo Konishi, Yuki Murakami, Chihiro Yoshida, Yoshiyuki Kasahara
Publikováno v:
International Journal of Tryptophan Research : IJTR
International Journal of Tryptophan Research, Vol 14 (2021)
International Journal of Tryptophan Research, Vol 14 (2021)
Viral infection and chronic maternal inflammation during pregnancy are correlated with a higher prevalence of autism spectrum disorder (ASD). However, the pathoetiology of ASD is not fully understood; moreover, the key molecules that can cross the pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a85d8718db4eba57c3c7bc83ccc46506
https://pubmed.ncbi.nlm.nih.gov/34262289
https://pubmed.ncbi.nlm.nih.gov/34262289