Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Yukio Hashizume"'
Autor:
Toshiaki Shibasaki, Yukio Hashizume, Kiyoshi Ohkawa, Masaharu Sakai, Kenichi Tashiro, Jun Nishihira, Tadashi Asakura, Yasuyuki Searashi
Publikováno v:
International Journal of Cancer. 94:171-177
A conjugate of doxorubicin and glutathione via glutaraldehyde (GSH-DXR) inhibited glutathione S-transferase (GST) activity of rat hepatoma AH66 cells, and treatment of the cells with GSH-DXR induced caspase-3 activation and DNA fragmentation. After t
Autor:
Yutaka Okawa, Yoshitaka Itoh, Tadashi Asakura, Nozomu Hibi, Kenichi Tashiro, Koji Takada, Kiyoshi Ohkawa, Yukio Hashizume, Junko Ueda
Publikováno v:
NeuroReport. 11:4007-4011
Clathrin- and AP-1-coated buds are present on immature secretory granules of endocrine cells that mature into clathrin-uncoated granules. The mechanism of clathrin and adaptor protein uncoating has remained obscure. Benzyloxycarbonyl-L-leucyl-L-leuci
Publikováno v:
Journal of Atmospheric Electricity. 15:37-44
Autor:
Kiyoshi Ohkawa, Takahiro Yamauchi, Kenji Soda, Tadao Oikawa, Tadashi Asakura, Yukio Hashizume
Publikováno v:
Anti-cancer drugs. 12(6)
To determine the cytotoxic mode of action of a glutathione (GSH)--doxorubicin (DXR) conjugate, which exhibited potent cytotoxicity against various multidrug-resistant as well as DXR-sensitive cell lines, the molecular interaction between covalent GSH
Autor:
Koji Takada, Tadashi Asakura, Nozomu Yanaihara, Kiyoshi Ohkawa, T Sawai, Yukio Hashizume, Yutaka Okawa
Publikováno v:
International Journal of Oncology.
P-glycoprotein (Pgp) is a plasma-membrane glycoprotein that confers multi-drug resistance (MDR) on cells and displays ATP-driven drug pumping. The possible contribution of calpain-mediated proteolytic pathways to the functional regulation of the Pgp