Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Yukio Akaneya"'
Autor:
Yukio Akaneya, Kazuhiro Sohya, Akihiko Kitamura, Fumitaka Kimura, Chris Washburn, Renping Zhou, Ipe Ninan, Tadaharu Tsumoto, Edward B Ziff
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12486 (2010)
Synaptogenesis is a fundamental step in neuronal development. For spiny glutamatergic synapses in hippocampus and cortex, synaptogenesis involves adhesion of pre and postsynaptic membranes, delivery and anchorage of pre and postsynaptic structures in
Externí odkaz:
https://doaj.org/article/9a3eb122eb744a23a8022c0740e79a68
Autor:
Yukio Akaneya
Publikováno v:
European Journal of Neuroscience. 25:1641-1646
In the developing visual cortex, the expression of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) subunit GluR4 precedes that of the other AMPAR subunits GluR1-3, and then declines to become almost absent in adults. The cur
Autor:
Tadaharu Tsumoto, Yukio Akaneya
Publikováno v:
The Journal of Neuroscience. 26:10209-10221
Although prostaglandin E2(PGE2) has a broad spectrum of biological activities that have been confirmed by previous studies, the roles of PGE2in synaptic plasticity such as long-term potentiation (LTP) in the CNS have yet to be characterized in detail
Publikováno v:
European Journal of Neuroscience. 14:1219-1228
Brain-derived neurotrophic factor (BDNF) rapidly enhances excitatory synaptic transmission in cortical slices. To date, however, a question of how long such an action persists remains unanswered as it is hard to record synaptic responses longer than
Publikováno v:
Neuropharmacology. 39:2255-2266
The mechanisms by which the NMDA receptor (NMDAR) induces excitotoxicity were investigated using a novel assay. We quantitated the capacity of wild type and mutant receptors for cell killing in CHO cells and cultured cortical neurons by measuring the
Publikováno v:
Journal of Neurophysiology. 76:4198-4201
1. Brain-derived neurotrophic factor (BDNF) has been reported to play a role in long-term potentiation (LTP) in hippocampus, but whether it is involved also in long-term depression (LTD) is not yet known. In this study, we tested whether BDNF and its
Publikováno v:
Brain Research. 704:175-183
Among the pathogenetic phenomena of Parkinson's disease, the character of the selective degeneration of nigrostriatal system with severe gliosis is not fully understood. Here, we have shown that dopaminergic neurons may be exclusively sensitive to el
Publikováno v:
Experimental Neurology. 136:44-52
To investigate the relationships between the central nervous system and interleukins, ventral mesencephalic cells from embryonic 17-day-old rats were cultured for 3 days in vitro (DIV) and exposed to interleukin-1 beta (IL-1 beta), interleukin-3 (IL-
Publikováno v:
Neuroscience Research. 23:55-63
It is known that dopaminergic neurons in the substantia nigra of the mesencephalon mainly project to the corpus striatum and neocortex, while the hippocampus receives major cholinergic projection from the septum. In the present study, the ventral mes
Publikováno v:
Neuroscience Research. 19:279-285
We have established an in vitro hypoxia model using cultured central nervous system neurons from postnatal 4-day-old (P4) rats, in which death may be correlated with N- methyl- d -aspartate (NMDA) -related toxicity. P4 rat hippocampal and neocortical