Zobrazeno 1 - 10
of 374
pro vyhledávání: '"Yukio, Tada"'
Autor:
Yukio Tada, Tosiya Sato
Publikováno v:
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Longitudinal ordinal data are commonly analyzed using a marginal proportional odds model for relating ordinal outcomes to covariates in the biomedical and health sciences. The generalized estimating equation (GEE) consistently est
Externí odkaz:
https://doaj.org/article/5a3dc11ce07646059653202f3ff872d4
Autor:
Satoshi Iwata, Andrew J. Pollard, Yukio Tada, Shinya Omoto, Risa Y. Shibata, Kenji Igarashi, Takahiro Hasegawa, Mari Ariyasu, Takuhiro Sonoyama
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract We assessed S-268019-b, a recombinant spike protein vaccine with a squalene-based adjuvant, for superiority in its immunogenicity over ChAdOx1 nCoV-19 vaccine among adults in Japan. In this multicenter, randomized, observer-blinded, phase 3
Externí odkaz:
https://doaj.org/article/817d308450f6499888e53a12afff8455
Autor:
Naotake Kobayashi, Norihito Sato, Yuko Fujimura, Tsuyoshi Kihara, Katsuji Sugita, Kouji Takahashi, Katsumi Koike, Tamio Sugawara, Yukio Tada, Hiroshi Nakai, Takayoshi Yoshikawa
Publikováno v:
ACS Omega, Vol 3, Iss 10, Pp 13647-13666 (2018)
Externí odkaz:
https://doaj.org/article/d165d037b7464779bcf5a8df0d389a63
Autor:
Iwao Osaka, Hiroto Ishiki, Takaaki Yokota, Yukio Tada, Hiroki Sato, Masaharu Okamoto, Eriko Satomi
Publikováno v:
ESMO Open, Vol 4, Iss 4 (2019)
Objective This post hoc, pooled, subgroup analysis of two randomised studies evaluated baseline characteristics that may influence the efficacy and safety of naldemedine in patients with opioid-induced constipation (OIC) and cancer.Methods Data for p
Externí odkaz:
https://doaj.org/article/1bcc5869a9ea4f1b88c9654d3a52a04f
Autor:
Tetsuya Saito, Yoshinobu Ichimura, Keiko Taguchi, Takafumi Suzuki, Tsunehiro Mizushima, Kenji Takagi, Yuki Hirose, Masayuki Nagahashi, Tetsuro Iso, Toshiaki Fukutomi, Maki Ohishi, Keiko Endo, Takefumi Uemura, Yasumasa Nishito, Shujiro Okuda, Miki Obata, Tsuguka Kouno, Riyo Imamura, Yukio Tada, Rika Obata, Daisuke Yasuda, Kyoko Takahashi, Tsutomu Fujimura, Jingbo Pi, Myung-Shik Lee, Takashi Ueno, Tomoyuki Ohe, Tadahiko Mashino, Toshifumi Wakai, Hirotatsu Kojima, Takayoshi Okabe, Tetsuo Nagano, Hozumi Motohashi, Satoshi Waguri, Tomoyoshi Soga, Masayuki Yamamoto, Keiji Tanaka, Masaaki Komatsu
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Dysregulation of p62 has been implicated in tumorigenesis. Here, the authors show that p62 promotes hepatocellular carcinoma by reprogramming glucose and glutamine metabolism through Nrf2 and present a novel compound that can inhibit p62 action thus
Externí odkaz:
https://doaj.org/article/f562794e07c0466a84d8f58624fb3b55
Publikováno v:
Proceeding of Heat Transfer and Transport Phenomena in Microscale.
Publikováno v:
Applied Sciences, Vol 10, Iss 6, p 2016 (2020)
This study investigates the factors affecting the formation of monodispersed thermosensitive gels and the parameters influencing the movement of gel particles containing N-isopropyl acrylamide in an aqueous polymeric solution in an upper heating syst
Externí odkaz:
https://doaj.org/article/a23f4120c81a4e41a8aeeab005b4d35d
Autor:
Naotake Kobayashi, Norihito Sato, Yuko Fujimura, Tsuyoshi Kihara, Katsuji Sugita, Kouji Takahashi, Katsumi Koike, Tamio Sugawara, Yukio Tada, Hiroshi Nakai, Takayoshi Yoshikawa
Publikováno v:
ACS Omega, Vol 4, Iss 4, Pp 6977-6978 (2019)
Externí odkaz:
https://doaj.org/article/fdb4daf687f24bdebc282ea868c82a00
Autor:
Takuhiro Sonoyama, Satoshi Iwata, Masaharu Shinkai, Naoko Iwata-Yoshikawa, Nozomi Shiwa-Sudo, Takuya Hemmi, Akira Ainai, Noriyo Nagata, Nobuaki Matsunaga, Yukio Tada, Tomoyuki Homma, Shinya Omoto, Risa Yokokawa Shibata, Kenji Igarashi, Tadaki Suzuki, Hideki Hasegawa, Mari Ariyasu
Publikováno v:
Vaccine.
In early 2020, developing vaccines was an urgent need for preventing COVID-19 from a contingency perspective.S-268019-a is a recombinant protein-based vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), comprising a modified
Autor:
Norihito Sato, Tamio Sugawara, Tsuyoshi Kihara, Katsumi Koike, Takayoshi Yoshikawa, Naotake Kobayashi, Katsuji Sugita, Yukio Tada
Publikováno v:
Chemical and Pharmaceutical Bulletin. 69:314-324
We explored orally effective thyrotropin-releasing hormone (TRH) mimetics, which show high central nervous system effects in structure-activity relationship studies based on in vivo antagonistic activity on reserpine-induced hypothermia (anti-hypothe