Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Yukinori Tamura"'
Autor:
Naoyuki Kawao, Yukinori Tamura, Yoshitaka Horiuchi, Katsumi Okumoto, Masato Yano, Kiyotaka Okada, Osamu Matsuo, Hiroshi Kaji
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123982 (2015)
Macrophages play crucial roles in repair process of various tissues. However, the details in the role of macrophages during bone repair still remains unknown. Herein, we examined the contribution of the tissue fibrinolytic system to the macrophage fu
Externí odkaz:
https://doaj.org/article/daf7606ea024405495014d6075a92daf
Autor:
Mika Yasui, Yukinori Tamura, Manabu Minami, Sei Higuchi, Risako Fujikawa, Taichi Ikedo, Manabu Nagata, Hidenori Arai, Toshinori Murayama, Masayuki Yokode
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136304 (2015)
With increasing body weight, macrophages accumulate in adipose tissue. There, activated macrophages secrete numerous proinflammatory cytokines and chemokines, giving rise to chronic inflammation and insulin resistance. Prostaglandin E2 suppresses mac
Externí odkaz:
https://doaj.org/article/61384677667a4c1f948f5d24781f2df9
Autor:
Li Mao, Naoyuki Kawao, Yukinori Tamura, Katsumi Okumoto, Kiyotaka Okada, Masato Yano, Osamu Matsuo, Hiroshi Kaji
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92686 (2014)
Previous studies suggest that fracture healing is impaired in diabetes; however, the underlying mechanism remains unclear. Here, we investigated the roles of plasminogen activator inhibitor-1 (PAI-1) in the impaired bone repair process by using strep
Externí odkaz:
https://doaj.org/article/bbe33f1afb5845ba83314de78f5cf0b5
Autor:
Yukinori Tamura, Masato Yano, Naoyuki Kawao, Katsumi Okumoto, Shigeru Ueshima, Hiroshi Kaji, Osamu Matsuo
Publikováno v:
Journal of Nutritional Science, Vol 2 (2013)
The effects of Enzamin on obesity-related metabolic disorders in obese db/db mice were examined to explore a novel agent for the prevention of insulin resistance. Db/db mice were treated with water containing Enzamin (0·1 and 1·0 %) for 8 weeks fro
Externí odkaz:
https://doaj.org/article/7a0b37f709c24897a689798b4cab1152
Autor:
Yukinori Tamura
Publikováno v:
Journal of Atherosclerosis and Thrombosis
Zinc is an essential micronutrient for human health and is involved in various biological functions, such as growth, metabolism, and immune function. In recent years, research on intracellular zinc dynamics has progressed, and it has become clear tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e9ccaa3e0f2f2c04f5d61d391a30564
http://europepmc.org/articles/PMC8592709
http://europepmc.org/articles/PMC8592709
Publikováno v:
Journal of Orthopaedic Science. 24:532-538
Once-weekly teriparatide treatment is widely used in the treatment of osteoporosis in Japan but the mechanisms causing the increase in bone mineral density (BMD) of the lumbar spine remain unknown. Methods: This prospective study examined the effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e1dbd653d4813174960c735872db1c5
https://doi.org/10.1016/j.jos.2018.10.028
https://doi.org/10.1016/j.jos.2018.10.028
Publikováno v:
Journal of Bone and Mineral Metabolism. 36:148-156
We recently revealed that plasminogen activator inhibitor-1 (PAI-1), a serine protease inhibitor, is involved in diabetes, osteoporosis and muscle wasting induced by glucocorticoid (GC) treatment in mice. In the present study, we investigated the det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17c85413af71922df61e594cd3638868
https://doi.org/10.1007/s00774-017-0825-8
https://doi.org/10.1007/s00774-017-0825-8
Publikováno v:
Biochemical and Biophysical Research Communications. 479:602-606
Skeletal muscle hypertrophy and wasting are induced by hypergravity and microgravity, respectively. However, the mechanisms by which gravity change regulates muscle mass still remain unclear. We previously reported that hypergravity increases muscle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcdb35914c8c17a09a6a482b3d8dfe8e
https://doi.org/10.1016/j.bbrc.2016.09.126
https://doi.org/10.1016/j.bbrc.2016.09.126
Autor:
Masayoshi Ishida, Hiroshi Kaji, Shinji Kurashimo, Katsumi Okumoto, Takeshi Shimoide, Yukinori Tamura, Naoyuki Kawao, Kohei Tatsumi, Osamu Matsuo, Kiyotaka Okada, Yoshitaka Horiuchi
Publikováno v:
Endocrinology. 159(4)
Delayed fracture healing is a clinical problem in diabetic patients. However, the mechanisms of diabetic delayed bone repair remain unknown. Here, we investigate the role of macrophages in diabetic delayed bone repair after femoral bone injury in str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e6c222c22fd6840a49abf184f7ac255
https://pubmed.ncbi.nlm.nih.gov/29534207
https://pubmed.ncbi.nlm.nih.gov/29534207
Autor:
Hiroshi Kaji, Osamu Matsuo, Masao Akagi, Yukinori Tamura, Naoyuki Kawao, Kiyotaka Okada, Akihito Shiomi, Katsumi Okumoto, Masato Yano
Publikováno v:
Bone. 79:233-241
The mechanism of postmenopausal osteoporosis is not fully understood. α2-Antiplasmin (α2-AP) is the primary inhibitor of plasmin in the fibrinolytic system, but is known to have activities beyond fibrinolysis. However, its role in bone metabolism a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::faeb338e09306a94b474c46bd56122f2
https://doi.org/10.1016/j.bone.2015.06.009
https://doi.org/10.1016/j.bone.2015.06.009