Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Yukinori Sawabe"'
Autor:
Yukinori Sawabe, Saori Tanaka, Shigekuni Hosogi, Toshio Inui, Chikao Shimamoto, Takashi Nakahari, Yoshinori Marunaka, Hitoshi Matsumura
Publikováno v:
Biomedical Research. 37:167-178
A PPARα (peroxisome proliferation activation receptor α) agonist (GW7647) activates nitric oxide synthase 1 (NOS1) to produce NO leading to cGMP accumulation in antral mucous cells. In this study, we examined how PPARα activates NOS1. The NO produ
Autor:
Yuko Takahashi, Daiki Mantoku, Hiroko Kuwabara, Saori Tanaka, Takashi Nakano, Hitoshi Matsumura, Nanae Sugiyama, Yoshinori Marunaka, Chikao Shimamoto, Takashi Nakahari, Yukinori Sawabe
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 307:G1169-G1179
In antral mucous cells, acetylcholine (ACh, 1 μM) activates Ca2+-regulated exocytosis, consisting of a peak in exocytotic events that declines rapidly (initial phase) followed by a second slower decline (late phase) lasting during ACh stimulation. G
Autor:
Yoshinori Marunaka, Hiroko Kuwabara, Saeko Harada, Hitoshi Matsumura, Saori Tanaka, Takashi Nakahari, Rina Tanaka, Yuka Kohda, Yuko Takahashi, Shigenori Ito, Chikao Shimamoto, Yukinori Sawabe
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 304:G773-G780
In antral mucous cells, acetylcholine (ACh, 1 μM) activates Ca2+-regulated exocytosis, consisting of an initial peak that declines rapidly (initial transient phase) followed by a second slower decline (late phase) lasting during ACh stimulation. The
Autor:
Saori, Tanaka, Shigekuni, Hosogi, Yukinori, Sawabe, Chikao, Shimamoto, Hitoshi, Matsumura, Toshio, Inui, Yoshinori, Marunaka, Takashi, Nakahari
Publikováno v:
Biomedical research (Tokyo, Japan). 37(3)
A PPARα (peroxisome proliferation activation receptor α) agonist (GW7647) activates nitric oxide synthase 1 (NOS1) to produce NO leading to cGMP accumulation in antral mucous cells. In this study, we examined how PPARα activates NOS1. The NO produ
Publikováno v:
MEMBRANE. 36:286-292
Autor:
Takashi Nakano, Yoshinori Marunaka, Chikao Shimamoto, Kimitaka Takitani, Takashi Nakahari, Hiroko Kuwabara, Hiroshi Tamai, Adel H. Saad, Akiko Sakai, Yukinori Sawabe, Hiroshi Mori
Publikováno v:
Experimental Physiology. 95:858-868
Indomethacin (IDM, 10 microm), not aspirin (ASA; 10 microm), enhanced the Ca(2+)-regulated exocytosis stimulated by 1 microm acetylcholine (ACh) in guinea-pig antral mucous cells. Indomethacin inhibits prostaglandin G/H (PGG/H) and 15R-hydroperoxy-ei
Autor:
Shinsaku Tokuda, Yoshinori Marunaka, Naomi Niisato, Kyosuke Nishio, Wataru Aoi, Yukinori Sawabe, Toshikazu Yoshikawa, Hiroaki Miyazaki
Publikováno v:
Cell Biology International. 31:1288-1291
Epithelial sodium channel (ENaC) plays a crucial role in controlling sodium reabsorption in the kidney keeping the normal blood pressure. We previously reported that the expression of ENaC mRNA in the kidney of Dahl salt-sensitive (DS) rats was abnor
Autor:
Yukinori Sawabe, Nobuko Taguchi, Yoshinori Marunaka, Yasutomi Hirai, Naomi Niisato, Hiroaki Miyazaki
Publikováno v:
Biochemical and Biophysical Research Communications. 327:915-919
The epithelial Na+ transport via an epithelial Na+ channel (ENaC) expressed in the lung epithelium would play a key role in recovery from lung edema at acute lung injury by removing the fluid in lung luminal space. The lung edema causes dysfunction o
Autor:
Saori, Tanaka, Nanae, Sugiyama, Yuko, Takahashi, Daiki, Mantoku, Yukinori, Sawabe, Hiroko, Kuwabara, Takashi, Nakano, Chikao, Shimamoto, Hitoshi, Matsumura, Yoshinori, Marunaka, Takashi, Nakahari
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 307(12)
In antral mucous cells, acetylcholine (ACh, 1 μM) activates Ca(2+)-regulated exocytosis, consisting of a peak in exocytotic events that declines rapidly (initial phase) followed by a second slower decline (late phase) lasting during ACh stimulation.
Autor:
Takashi Nakahari, Saori Tanaka, Yuko Takahashi, Hitoshi Matsumura, Takashi Nakano, Hiroko Kuwabara, Chikao Shimamoto, Yukinori Sawabe, Saeko Harada
Publikováno v:
European journal of pharmacology. 721(1-3)
Levtiracetam (Lev), an inhibitor of SV2A (synaptic vesicle protein A2), affected the ATP-dependent priming of Ca 2+ -regulated exocytosis in antral mucous cells of guinea pig. In antral mucous cells, the Ca 2+ -regulated exocytosis, which is activate