Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Yukino Urata"'
1
Cross-linked human serum albumin dimer has the potential for use as a plasma-retaining agent for the fatty acid-conjugated antidiabetic drugs
Autor: Masaki Otagiri, Keiichi Kawai, Hakaru Seo, Teruyuki Komatsu, Keishi Yamasaki, Toru Maruyama, Kazuaki Taguchi, Victor Tuan Giam Chuang, Yukino Urata, Makoto Anraku, Ryota Tanaka
Publikováno v: Journal of Pharmacy and Pharmacology. 67:255-263
Objectives The half-life of fatty acid-conjugated antidiabetic drugs are prolonged through binding to albumin, but this may not occur in diabetic patients with nephropathy complicated with hypoalbuminemia. We previously showed that human serum albumi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f1e2c97661558073e606f52779bd2a
https://doi.org/10.1111/jphp.12338
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2
Superior Plasma Retention of a Cross-Linked Human Serum Albumin Dimer in Nephrotic Rats as a New Type of Plasma Expander
Autor: Eishun Tsuchida, Toru Maruyama, Teruyuki Komatsu, Masaki Otagiri, Kazuaki Taguchi, Makoto Anraku, Yukino Urata, Hiroshi Watanabe, Keiichi Kawai
Publikováno v: Drug Metabolism and Disposition. 38:2124-2129
Human serum albumin (HSA) is used clinically as a plasma expander in patients with hypoalbuminemia and can also function as a drug carrier. However, the administered HSA is readily eliminated from the blood circulation under pathological conditions,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3c029692d3dc85a65e7f5a14aa9af7d
https://doi.org/10.1124/dmd.109.031989
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4
Health Promotion Intervention by Primary Care Pharmacists-Survey on Awareness of Folic Acid and Effectiveness of Information Provided on Appropriate Intake
Autor: Hiroki Sato, Yosuke Kono, Hiroshi Watanabe, Kazuki Shimoishi, Yu Ishima, Gen Yamamoto, Yoshiro Okayama, Toru Maruyama, Makoto Anraku, Hakaru Seo, Daisuke Kadowaki, Yukino Urata, Yoko Watanabe
Publikováno v: Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 36:533-541
Recently,substantial epidemiological research has clarified that folic acid decreases the incidence of fetal dysraphia such as spina bifida and anencephaly.Consequently,the Ministry of Health,Labour and Welfare (MHLW) now recommends that women of chi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f415b79f320ba333953aacc327d6824d
https://doi.org/10.5649/jjphcs.36.533
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5
Hemoglobin Vesicles, Polyethylene Glycol (PEG)ylated Liposomes Developed as a Red Blood Cell Substitute, Do Not Induce the Accelerated Blood Clearance Phenomenon in Mice
Autor: Yukino Urata, Kazuaki Taguchi, Eishun Tsuchida, Toru Maruyama, Hirohisa Horinouchi, Makoto Anraku, Hiromi Sakai, Daisuke Kadowaki, Hiroshi Watanabe, Koichi Kobayashi, Masaki Otagiri
Publikováno v: Drug Metabolism and Disposition. 37:2197-2203
The hemoglobin vesicle (HbV) is an artificial oxygen carrier encapsulating a concentrated hemoglobin solution in a liposome of which the surface is covered with polyethylene glycol (PEG). It was recently reported that repeated injections of PEGylated
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd65f09ceb7edfb81464cdc001da86d9
https://doi.org/10.1124/dmd.109.028852
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6
Possible false-negative results on therapeutic drug monitoring of phenytoin using a particle enhanced turbidimetric inhibition immunoassay in a patient with a high level of IgM
Autor: Yuhuki Enoki, Toru Maruyama, Eiko Fukunaga, Junji Saruwatari, Yu Ishima, Kazufumi Iwata, Kentaro Ueda, Daisuke Kadowaki, Hiroshi Watanabe, Takumi Shirouzono, Yukino Urata, Hiroshi Moriuchi, Motoki Imamura, Keiji Aizawa, Sumio Hirata, Kenshiro Hirata
Publikováno v: Therapeutic drug monitoring. 36(5)
In this report, the authors described the unusual case of a patient in whom the plasma phenytoin concentration was unexpectedly not detected on a particle-enhanced turbidimetric inhibition immunoassay (PETINIA) technique, a typical immunoassay for ph
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b9cb56db95c98f54fb3ee68107e033b
https://pubmed.ncbi.nlm.nih.gov/25478903
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7
Pharmacokinetic study of enclosed hemoglobin and outer lipid component after the administration of hemoglobin vesicles as an artificial oxygen carrier
Autor: Toshiya Kai, Eishun Tsuchida, Yukino Urata, Kazuaki Taguchi, Toru Maruyama, Hirohisa Horinouchi, Masaki Otagiri, Hiromi Sakai, Hiroshi Watanabe, Makoto Anraku, Koichi Kobayashi
Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 37(7)
The hemoglobin vesicle (HbV) is an artificial oxygen carrier that encapsulates a concentrated Hb solution in lipid vesicles (liposomes). The pharmacokinetic properties of HbV were investigated in mice and rats. With use of HbV in which the internal H
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40bb9aab7ceff046dc2661bfdf978900
https://pubmed.ncbi.nlm.nih.gov/19364827
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