Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yukimi Yoneyama"'
Autor:
Ola Fjellström, Niklas Larsson, Shin-Ichiro Yasuda, Takuma Tsuchida, Takahiro Oguma, Anna Marley, Charlotte Wennberg-Huldt, Daniel Hovdal, Hajime Fukuda, Yukimi Yoneyama, Kazuyo Sasaki, Anders Johansson, Sara Lundqvist, Johan Brengdahl, Richard J Isaacs, Daniel Brown, Stefan Geschwindner, Lambertus Benthem, Claire Priest, Andrew Turnbull
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145849 (2015)
Type 2 diabetes (T2D) occurs when there is insufficient insulin release to control blood glucose, due to insulin resistance and impaired β-cell function. The GPR39 receptor is expressed in metabolic tissues including pancreatic β-cells and has been
Externí odkaz:
https://doaj.org/article/64efe16b0e9f431eb9ae335a14c2bfc8
Autor:
Stefan Geschwindner, Andrew V. Turnbull, Sara Lundqvist, Anna Marley, Kazuyo Sasaki, Niklas Larsson, Ola Fjellström, Charlotte Wennberg-Huldt, Richard J. Isaacs, Anders Johansson, Claire Priest, Lambertus Benthem, Yukimi Yoneyama, Johan Brengdahl, Daniel Hovdal, Shin-ichiro Yasuda, Hajime Fukuda, Takuma Tsuchida, Daniel G. Brown, Takahiro Oguma
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145849 (2015)
PLoS ONE
PLoS ONE
Type 2 diabetes (T2D) occurs when there is insufficient insulin release to control blood glucose, due to insulin resistance and impaired β-cell function. The GPR39 receptor is expressed in metabolic tissues including pancreatic β-cells and has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a90e8b6ee68eaf26d0dd8fbb6edbb0c2
http://europepmc.org/articles/PMC4697807?pdf=render
http://europepmc.org/articles/PMC4697807?pdf=render
Autor:
Ryoichi Ando, Satoshi Yuki, Takuro Niwa, Takahide Kaji, Hiroaki Ueno, Hideo Kubodera, Ken-Ichi Saito, Jun-ichi Eguchi, Kenji Fukunaga, Shoichi Asano, Fumiaki Uehara, Keiichi Aritomo, Shinji Sunada, Aya Shoda, Masaki Shinoda, Shinji Tanaka, Yukimi Yoneyama, Kazutoshi Watanabe
Publikováno v:
Bioorganicmedicinal chemistry letters. 23(24)
The discovery of a series of 6-(4-pyridyl)pyrimidin-4(3H)-ones derived from a hit compound with low molecular weight and sufficient chemical space is reported. Transformation of substituents led to subnanomolar potent inhibitors with in vivo tau phos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56b5fb6d1bc6f131ecb58c4142b376e8
https://pubmed.ncbi.nlm.nih.gov/24094818
https://pubmed.ncbi.nlm.nih.gov/24094818
Autor:
Akiharu Fujino, Kazuyoshi Suzuki, Jun Tatsuno, Seiu Iida, Tomio Inokuchi, Yukimi Yoneyama, Masato Iwamoto, Kunihiko Shibata, Minako Nozawa
Publikováno v:
Drug Metabolism and Pharmacokinetics. 5:699-710
The absorption, distribution, metabolism, excretion and accumulation of Betaxolol were investigated after repeated oral administration of 14C-Betaxolol (5mg/kg/day) to male rats for 21 days. The effect of Betaxolol on the hepatic drug-metabolizing en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66252d85aefb1296e87680c650414d93
https://doi.org/10.2133/dmpk.5.699
https://doi.org/10.2133/dmpk.5.699
Publikováno v:
Drug Metabolism and Pharmacokinetics. 5:711-721
The absorption, excretion and metabolism of Betaxolol were investigated in male and female dogs after oral or intravenous administration of 14C-Betaxolol.1. After oral administration of 14C-Betaxolol(1mg/kg) to male and female dogs, the plasma levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d98435c119b25d799341a196ce69bd74
https://doi.org/10.2133/dmpk.5.711
https://doi.org/10.2133/dmpk.5.711
Autor:
Seiu IIDA, Tomio INOKUCHI, Masato IWAMOTO, Masayuki SUZUKI, Yukimi YONEYAMA, Akiharu FUJINO, Kunihiko SHIBATA
Publikováno v:
Drug Metabolism and Pharmacokinetics. 5:675-697
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f20a54b64e47b75bf1b11599e9722a3f
https://doi.org/10.2133/dmpk.5.675
https://doi.org/10.2133/dmpk.5.675