Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Yukimasa Nozaki"'
Publikováno v:
Cancer Chemotherapy and Pharmacology. 40:513-520
Purpose: During our search for new microtubule effectors as anticancer agents, we have found that a small synthetic molecule designated GS-164 interferes with the assembly of porcine microtubule proteins and has cytotoxic activity against a wide rang
Publikováno v:
The Journal of Antibiotics. 48:12-20
We detected potent angiostatic activity in a MeOH extract from the mycelia of microbial strain S-45628 in the chick chorioallantoic membrane (CAM) assay. The producer was taxonomically characterized as Streptomyces purpurascens. Active principles des
Publikováno v:
ChemInform. 26
We detected potent angiostatic activity in a MeOH extract from the mycelia of microbial strain S-45628 in the chick chorioallantoic membrane (CAM) assay. The producer was taxonomically characterized as Streptomyces purpurascens. Active principles des
Autor:
Nozomi Katayama, Shigetoshi Tsubotani, Masahiro Kondo, Setsuo Harada, Hideo Ono, Yukimasa Nozaki
Publikováno v:
The Journal of Antibiotics. 45:10-19
A Gram-negative bacterium was found to produce new antibacterial antibiotics, sperabillins A, B, C and D, and the producing bacterium was characterized and identified as Pseudomonas fluorescens YK-437. Sperabillins were isolated by column chromatogra
Publikováno v:
ChemInform. 32
A novel Ras-farnesyltransferase inhibitor designated TAN-1813 was isolated from the culture broth of a fungus strain, FL-41510, isolated as a plant endophyte. The producer was taxonomically characterized as Phoma sp. FL-41510. TAN-1813 inhibited rat
Autor:
Masayuki Muroi, Yukimasa Nozaki, Katsuichi Sudo, Tsuneaki Hida, Takafumi Ishii, Sffigemi Iinuma, Tsuneo Kanamaru
Publikováno v:
The Journal of antibiotics. 46(4)
A potent angiogenesis-inhibitory compound TAN-1120 was found to be produced by a Streptomyces species isolated from a soil sample. The producing organism was characterized as a new subspecies of S. triangulatus and named S. triangulatus subsp. angios
Publikováno v:
The Journal of antibiotics. 46(1)
A Gram-negative bacterium was found to produce new iron-containing peptide antibiotics, ferrocins A, B, C and D, and the producing bacterium was characterized and identified as Pseudomonas fluorescens YK-310. These new antibiotics showed antibacteria
Publikováno v:
The Journal of antibiotics. 43(3)
Two new nucleotide antibiotics, fosfadecin and fosfocytocin, have been isolated from the culture filtrates of Pseudomonas viridiflava PK-5 and Pseudomonas fluorescens PK-52, respectively. These antibiotics were purified by column chromatographies usi
Publikováno v:
The Journal of Antibiotics. 42:84-93
Lactivicin is moderately active against a wide range of Gram-negative bacteria and highly active against Gram-positive bacteria. It shows various biological activities commonly observed with beta-lactam antibiotics, such as higher activity against be
Publikováno v:
Agricultural and Biological Chemistry. 49:677-684
Sulfate transport-negative mutants were derived from Streptomyces griseus subsp. cryophilus C-19393 which coproduced sulfated and unsulfated carbapenem antibiotics. These mutants were successfully obtained by two approaches: (1) the requirement of th