Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Yukimasa, Takeda"'
Autor:
Yukimasa Takeda, Ping Dai
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Brown fat is a therapeutic target for the treatment of obesity-associated metabolic diseases. However, nutritional intervention strategies for increasing the mass and activity of human brown adipocytes have not yet been established. To ident
Externí odkaz:
https://doaj.org/article/0465bf6fa82b48268147d604ce517e63
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Brown adipocytes are potential therapeutic targets for the prevention of obesity-associated metabolic diseases because they consume circulating glucose and fatty acids for heat production. Angiotensin II (Ang II) peptide is involved in the p
Externí odkaz:
https://doaj.org/article/bd54b998b16b4560bab5aadd4958d670
Autor:
Yukimasa Takeda, Ping Dai
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Human brown fat is a potential therapeutic target for preventing obesity and related metabolic diseases by dissipating energy as heat through uncoupling protein 1 (UCP1). We have previously reported a method to obtain chemical compound-induc
Externí odkaz:
https://doaj.org/article/bca483077b70425d9668c80df6b247e2
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Brown adipogenesis contributes to controlling systemic energy balance by enhancing glucose and lipid consumptions. We have previously reported chemical compound-induced brown adipocytes (ciBAs) directly converted from human dermal fibroblast
Externí odkaz:
https://doaj.org/article/ae4a8367c631408ba56cd5e38e70990b
Autor:
Yukimasa Takeda, Ping Dai
Publikováno v:
Cells, Vol 11, Iss 13, p 2038 (2022)
Thermogenic brown fat contributes to metabolic health in adult humans. Obese conditions are known to repress adipose-tissue browning and its activity. Herein, we found that chronic fatty acid (FA) depletion induced uncoupling protein 1 (UCP1) express
Externí odkaz:
https://doaj.org/article/c967d2ba95ee4049a28d8a9ebbd4d9e3
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Brown adipocytes play an important role in human energy metabolism and prevention of obesity and diabetes. Induced pluripotent stem cells (iPSCs) represent a promising source for brown adipocytes; however, exogenous gene induction is general
Externí odkaz:
https://doaj.org/article/5912ca5dc598460a88e8292ed8005d9a
Publikováno v:
宮城学院女子大学発達科学研究 = Journal of Developmental Science. 22:89-102
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::3223e935142b626f0ac80db95e24dc1a
http://id.nii.ac.jp/1502/00000631/
http://id.nii.ac.jp/1502/00000631/
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2023
Retinoic acid receptor-related orphan receptors (ROR, nomenclature as agreed by the NC-IUPHAR Subcommittee on Nuclear Hormone Receptors [11, 3]) have yet to be assigned a definitive endogenous ligand, although RORα may be synthesized with a ‘capt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d7fcd4d543fdda0b5cf8d5b63c9f8df
https://doi.org/10.2218/gtopdb/f88/2023.1
https://doi.org/10.2218/gtopdb/f88/2023.1
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157138 (2016)
The transcription factor Glis-similar 3 (Glis3) has been implicated in the development of neonatal, type 1 and type 2 diabetes. In this study, we examined the spatiotemporal expression of Glis3 protein during embryonic and neonatal pancreas developme
Externí odkaz:
https://doaj.org/article/ca381ce002a34ba58f0c48c59981ec4e
Autor:
Susan H Smith, Carlos E Peredo, Yukimasa Takeda, Thi Bui, Jessica Neil, David Rickard, Elizabeth Millerman, Jean-Philippe Therrien, Edwige Nicodeme, Jean-Marie Brusq, Veronique Birault, Fabrice Viviani, Hans Hofland, Anton M Jetten, Javier Cote-Sierra
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0147979 (2016)
Psoriasis is a chronic inflammatory skin disorder involving marked immunological changes. IL-17-targeting biologics have been successful in reducing the disease burden of psoriasis patients with moderate-to-severe disease. Unfortunately, the stratum
Externí odkaz:
https://doaj.org/article/eafec2826fc340719a00dd38c007ee18