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Trends and Characteristics in Health Care-related Deaths Investigated through Medico-legal Autopsies after System Changes in Japan

Autor: Rutsuko, Yamaguchi, Yohsuke, Makino, Go, Inokuchi, Kenji, Ishihara, Suguru, Torimitsu, Fumiko, Chiba, Yumi, Hoshioka, Syumari, Urabe, Yukiko, Oya, Ayumi, Motomura, Daisuke, Yajima, Hirotaro, Iwase

Publikováno v: Journal of law and medicine. 29(2)

In Japan, a new cause-of-death investigation system and related new laws were enacted in the mid-2010s. These laws provided for an autopsy system for non-criminal unnatural deaths and a medical accident investigation system outside the criminal justi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7c4e5e751bc2ef4b23b2cf30b46cf31d
https://pubmed.ncbi.nlm.nih.gov/35819389

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Tumor microenvironment in gastric cancers

Autor: Kazuhiko Koike, Yukiko Oya, Yoku Hayakawa

Publikováno v: Cancer Science

The tumor microenvironment favors the growth and expansion of cancer cells. Many cell types are involved in the tumor microenvironment such as inflammatory cells, fibroblasts, nerves, and vascular endothelial cells. These stromal cells contribute to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b040f6fbd6827670ed7130a7433a3bd
http://europepmc.org/articles/PMC7419059

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Dysregulated Immune Responses by ASK1 Deficiency Alter Epithelial Progenitor Cell Fate and Accelerate Metaplasia Development during H. pylori Infection

Autor: Ken Kurokawa, Hayato Nakagawa, Shin Maeda, Keisuke Tateishi, Nobumi Suzuki, Masahiro Hata, Yukiko Oya, Yoshihiro Hirata, Junya Arai, Hiroaki Fujiwara, Sohei Abe, Mayo Tsuboi, Yoku Hayakawa, Kazuhiko Koike

Publikováno v: Microorganisms
Volume 8
Issue 12

The mechanism of H. pylori-induced atrophy and metaplasia has not been fully understood. Here, we demonstrate the novel role of Apoptosis signal-regulating kinase 1 (ASK1) and downstream MAPKs as a regulator of host immune responses and epithelial ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c16f00607f79b64c327141b558b53b52
http://europepmc.org/articles/PMC7765114

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Akademický článek

Association of taurine intake with changes in physical fitness among community-dwelling middle-aged and older Japanese adults: an 8-year longitudinal study

Autor: Takashi Domoto, Kazuyoshi Kise, Yukiko Oyama, Kanae Furuya, Yuki Kato, Yukiko Nishita, Rumi Kozakai, Rei Otsuka

Publikováno v: Frontiers in Nutrition, Vol 11 (2024)

IntroductionTaurine has diverse valuable biological functions, including antioxidant activity and regulation of osmotic pressure. Maintaining physical fitness from middle age is important for healthy life expectancy. Although taurine administration i

Externí odkaz: https://doaj.org/article/d37fb63229e34ec6b90ad9e8b0d152c0

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Down-regulation of histone deacetylase 4, −5 and −6 as a mechanism of synergistic enhancement of apoptosis in human lung cancer cells treated with the combination of a synthetic retinoid, Am80 and green tea catechin

Autor: Koichi Shudo, Tatsuro Watanabe, Sonthaya Umsumarng, Hiroyuki Kagechika, Keisuke Iida, Miki Kanno, Yukiko Oya, Anchalee Rawangkan, Kaori Suzuki, Anupom Mondal, Hirota Fujiki, Zhenghao Li, Masami Suganuma

Publikováno v: The Journal of Nutritional Biochemistry. 42:7-16

(-)-Epigallocatechin gallate (EGCG), a green tea catechin, acts as a synergist with various anticancer drugs, including retinoids. Am80 is a synthetic retinoid with a different structure from all-trans-retinoic acid: Am80 is now clinically utilized a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0858b1dc604b351463aa8e12d2bbf41e
https://doi.org/10.1016/j.jnutbio.2016.12.015

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Age estimation from ossification of sternum and true ribs using 3D post-mortem CT images in a Japanese population

Autor: Yukiko Oya, Maiko Yoshida, Shumari Urabe, Hirotaro Iwase, Sukon Prasitwattanaseree, Tawachai Monum, Daisuke Yajima, Suguru Torimitsu, Yumi Hoshioka, Fumiko Chiba, Yohsuke Makino

Publikováno v: Legal medicine (Tokyo, Japan). 43

Age estimation of cadavers from post-mortem “chest plate” using conventional radiography, which involves radiographic assessment of ossification around the sternum and rib ends, has been evaluated without fruitful results. This study examined the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1fac27bec9431f34975fbc02c845b97
https://pubmed.ncbi.nlm.nih.gov/31954957

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BHLHA15-positive Secretory Precursor Cells Can Give Rise to Tumors in Intestine and Colon in Mice

Publikováno v: Paediatrics Publications

Background & Aims The intestinal epithelium is maintained by long-lived intestinal stem cells (ISCs) that reside near the crypt base. Above the ISC zone, there are short-lived progenitors that normally give rise to lineage-specific differentiated cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00bbe0fdad1108d1b20121cd6fe727b4
https://europepmc.org/articles/PMC6409180/

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Inhibition of TNFα-interacting protein α (Tipα)-associated gastric carcinogenesis by BTG2

Autor: Preethi, Devanand, Yukiko, Oya, Santhoshkumar, Sundaramoorthy, Kye Yong, Song, Tatsuro, Watanabe, Yasuhito, Kobayashi, Yoshihiko, Shimizu, Soon Auck, Hong, Masami, Suganuma, In Kyoung, Lim

Publikováno v: Experimental & Molecular Medicine

To understand the regulation of Helicobacter pylori (H. pylori)-associated gastric carcinogenesis, we examined the effect of B-cell translocation gene 2 (BTG2) expression on the biological activity of Tipα, an oncoprotein secreted from H. pylori. BT

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0164eed352b35fb59c73eb771ba4f17b
https://pubmed.ncbi.nlm.nih.gov/29472702

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