Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Yukiko Nishiguch"'
Autor:
Takamitsu Sasaki, Rina Fujiwara‐Tani, Shingo Kishi, Shiori Mori, Yi Luo, Hitoshi Ohmori, Isao Kawahara, Kei Goto, Yukiko Nishiguchi, Takuya Mori, Masayuki Sho, Masuo Kondo, Hiroki Kuniyasu
Publikováno v:
Cancer Medicine, Vol 8, Iss 15, Pp 6700-6708 (2019)
Abstract Claudin (CLDN) family comprises of protein that form a tight junction, and is involved in regulating polarity and differentiation of cells. Here, we aimed to investigate the effects of inhibiting CLDN4 in pancreatic ductal carcinomas (PDC).
Externí odkaz:
https://doaj.org/article/f44780c7755b405b8bed9c7cfacb653f
Autor:
Yudai Hojo, Shingo Kishi, Shiori Mori, Rina Fujiwara-Tani, Takamitsu Sasaki, Kiyomu Fujii, Yukiko Nishiguchi, Chie Nakashima, Yi Luo, Hisashi Shinohara, Hiroki Kuniyasu
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 4002 (2022)
The use of molecular-targeted drugs in the treatment of gastric cancer is increasing. However, the variety of molecular-targeted drugs in gastric cancer is still limited, and the development of new molecular-targeted therapies is required. The effect
Externí odkaz:
https://doaj.org/article/c3ba461418544b7590c180663080c667
Autor:
Ruiko Ogata, Shiori Mori, Shingo Kishi, Rika Sasaki, Naoya Iwata, Hitoshi Ohmori, Takamitsu Sasaki, Yukiko Nishiguchi, Chie Nakashima, Kei Goto, Isao Kawahara, Rina Fujiwara-Tani, Hiroki Kuniyasu
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1, p 225 (2021)
Cancer dormancy is a state characterized by the quiescence of disseminated cancer cells, and tumor recurrence occurs when such cells re-proliferate after a long incubation period. These cancer cells tend to be treatment resistant and one of the barri
Externí odkaz:
https://doaj.org/article/36d1cb7c780f4e42877d0c070ee612ef
Autor:
Rina Fujiwara-Tani, Ayaka Okamoto, Hiroyuki Katsuragawa, Hitoshi Ohmori, Kiyomu Fujii, Shiori Mori, Shingo Kishi, Takamitsu Sasaki, Chie Nakashima, Isao Kawahara, Yudai Hojo, Yukiko Nishiguchi, Takuya Mori, Takeshi Mizumoto, Kenta Nagai, Yi Luo, Hiroki Kuniyasu
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 23, p 12724 (2021)
Gastric hyperplastic polyps (GHP) are frequently found to be benign polyps and have been considered to have a low carcinogenic potential. The characteristics of the hyperplastic polyp-associated gastric cancer (HPAGC) remain unclear. Therefore, we an
Externí odkaz:
https://doaj.org/article/822e3229217147d69a9c39624b3122ad
Autor:
Shiori Mori, Rina Fujiwara-Tani, Shingo Kishi, Takamitsu Sasaki, Hitoshi Ohmori, Kei Goto, Chie Nakashima, Yukiko Nishiguchi, Isao Kawahara, Yi Luo, Hiroki Kuniyasu
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 15, p 8232 (2021)
β-Casomorphin-7 (BCM) is a degradation product of β-casein, a milk component, and has been suggested to affect the immune system. However, its effect on mucosal immunity, especially anti-tumor immunity, in cancer-bearing individuals is not clear. W
Externí odkaz:
https://doaj.org/article/e2960917e58f466ab2321c4d0fcc70b1
Autor:
Shingo Kishi, Yukiko Nishiguchi, Kanya Honoki, Shiori Mori, Rina Fujiwara-Tani, Takamitsu Sasaki, Kiyomu Fujii, Isao Kawahara, Kei Goto, Chie Nakashima, Akira Kido, Yasuhito Tanaka, Yi Luo, Hiroki Kuniyasu
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 10, p 5185 (2021)
Advanced glycation end products (AGEs) are produced in response to a high-glucose environment and oxidative stress and exacerbate various diseases. Nε-(Carboxymethyl)lysine (CML) is an AGE that is produced by the glycation of lysine residues of prot
Externí odkaz:
https://doaj.org/article/bfdd4536b1804d9cb388d7b318cadf26
Autor:
Rina Fujiwara-Tani, Kiyomu Fujii, Shiori Mori, Shingo Kishi, Takamitsu Sasaki, Hitoshi Ohmori, Chie Nakashima, Isao Kawahara, Yukiko Nishiguchi, Takuya Mori, Masayuki Sho, Masuo Kondoh, Yi Luo, Hiroki Kuniyasu
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 11, p 3840 (2020)
Sessile serrated adenoma/polyp with dysplasia (SSA/P-D) is an SSA/P with cellular dysplasia and has a higher risk of progressing to colon carcinogenesis. Previously, we reported that tight junction impairment by Clostridium perfringens enterotoxin (C
Externí odkaz:
https://doaj.org/article/3fed65b0dc2d44aaa23fd2c1e0074120
Autor:
Tomonori Sasahira, Miyako Kurihara-Shimomura, Yukiko Nishiguchi, Hiroyuki Shimomura, Tadaaki Kirita
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 10, p 3655 (2020)
Because oral squamous cell carcinomas (OSCCs) have a high potential for locoregional invasion and nodal metastasis, early detection and treatment are essential. A LAP2, emerin, MAN1 (LEM) domain containing 1 (LEMD1) is associated with local progressi
Externí odkaz:
https://doaj.org/article/9a151e124f7a46fb80f7f0fa9ed9d1b8
Autor:
Takamitsu Sasaki, Shiori Mori, Shingo Kishi, Rina Fujiwara-Tani, Hitoshi Ohmori, Yukiko Nishiguchi, Yudai Hojo, Isao Kawahara, Chie Nakashima, Kiyomu Fujii, Yi Luo, Hiroki Kuniyasu
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 11, p 3877 (2020)
Proton pump inhibitors (PPIs) are administered commonly to aged people; however, their effect on colorectal cancer (CRC) has still not been fully elucidated. Here, we examined the effect of PPIs and consequent alkalization on CRC cells. PPI administr
Externí odkaz:
https://doaj.org/article/9a683af8d2194941b4f6c6f785745933
Autor:
Yukiko Nishiguchi, Naohide Oue, Rina Fujiwara-Tani, Takamitsu Sasaki, Hitoshi Ohmori, Shingo Kishi, Shiori Mori, Takuya Mori, Naoya Ikeda, Sohei Matsumoto, Kohei Wakatsuki, Yi Luo, Wataru Yasui, Masayuki Sho, Hiroki Kuniyasu
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 1, p 254 (2019)
The role of metastasis-related genes in cisplatin (CDDP) chemoresistance in gastric cancer is poorly understood. Here, we examined the expression of four metastasis-related genes (namely, c-met, HMGB1, RegIV, PCDHB9) in 39 cases of gastric cancer tre
Externí odkaz:
https://doaj.org/article/fb02692fb4e44ffa9cf5db3af0acb4e6