Zobrazeno 1 - 10
of 307
pro vyhledávání: '"Yukiko K, Hayashi"'
Publikováno v:
Journal of Physiological Sciences, Vol 73, Iss 1, Pp 1-9 (2023)
Abstract Emery–Dreifuss muscular dystrophy (EDMD), caused by mutations in genes encoding nuclear envelope proteins, is clinically characterized by muscular dystrophy, early joint contracture, and life-threatening cardiac abnormalities. To elucidate
Externí odkaz:
https://doaj.org/article/ff60e5882ff144e3813910c5e0b0b3ba
Autor:
Wirongrong Wongkitikamjorn, Eiji Wada, Jun Hosomichi, Hideyuki Maeda, Sirichom Satrawaha, Haixin Hong, Ken-ichi Yoshida, Takashi Ono, Yukiko K. Hayashi
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Gestational intermittent hypoxia (IH) is a hallmark of obstructive sleep apnea that occurs frequently during pregnancy, and effects caused by this environmental change during pregnancy may be transmitted to the offspring. In this study, we aimed to c
Externí odkaz:
https://doaj.org/article/4fd564fbabdf48bba2a1cdaf8fc7c5a7
Autor:
Nozomi Hayashiji, Genri Kawahara, Xing Xu, Tomohiko Fukuda, Aurelien Kerever, Jianguo Gu, Yukiko K. Hayashi, Eri Arikawa-Hirasawa
Publikováno v:
Cells, Vol 12, Iss 1, p 144 (2022)
Glycosylation is an important mechanism regulating various biological processes, including intercellular signaling and adhesion. α-1,6-fucosyltransferase (Fut8) belongs to a family of enzymes that determine the terminal structure of glycans. Fut8 is
Externí odkaz:
https://doaj.org/article/c03a7b2976bb440c8089e6f56e9d7d41
Publikováno v:
Skeletal Muscle, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Background Chronic increases in the levels of the inflammatory cytokine interleukin-6 (IL-6) in serum and skeletal muscle are thought to contribute to the progression of muscular dystrophy. Dystrophin/utrophin double-knockout (dKO) mice deve
Externí odkaz:
https://doaj.org/article/7099b97336f24c1da704bbb1c90d7f3e
Autor:
Masayuki Nakamori, Kohei Hamanaka, James D. Thomas, Eric T. Wang, Yukiko K. Hayashi, Masanori P. Takahashi, Maurice S. Swanson, Ichizo Nishino, Hideki Mochizuki
Publikováno v:
Cell Reports, Vol 21, Iss 5, Pp 1240-1252 (2017)
Summary: Myotonic dystrophy types 1 (DM1) and 2 (DM2) are dominantly inherited neuromuscular disorders caused by a toxic gain of function of expanded CUG and CCUG repeats, respectively. Although both disorders are clinically similar, congenital myoto
Externí odkaz:
https://doaj.org/article/1673442e67eb40de8ee555f59692717c
Autor:
Mariko Okubo, Kanako Goto, Hirofumi Komaki, Harumasa Nakamura, Madoka Mori-Yoshimura, Yukiko K. Hayashi, Satomi Mitsuhashi, Satoru Noguchi, En Kimura, Ichizo Nishino
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 12, Iss 1, Pp 1-7 (2017)
Abstract Background Duchenne muscular dystrophy (DMD) is the most common disease in children caused by mutations in the DMD gene, and DMD and Becker muscular dystrophy (BMD) are collectively called dystrophinopathies. Dystrophinopathies show a comple
Externí odkaz:
https://doaj.org/article/8c1d0ebcb269436cb32889cbfab94b81
Autor:
Eiji Wada, Megumi Kato, Kaori Yamashita, Hiroko Kokuba, Wen-Chen Liang, Gisèle Bonne, Yukiko K Hayashi
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0221512 (2019)
Laminopathies are tissue-selective diseases that affect differently in organ systems. Mutations in nuclear envelopes, emerin (Emd) and lamin A/C (Lmna) genes, cause clinically indistinguishable myopathy called Emery-Dreifuss muscular dystrophy (EDMD)
Externí odkaz:
https://doaj.org/article/a13977dcdb594955b74c7c9871bdbf00
Autor:
Katsuya Iijima, Tamao Endo, Wako Yumura, Masahiro Akishita, Yukiko K. Hayashi, Yasuyoshi Ouchi, Naoki Kashihara, Hidenori Arai, Kouetsu Ogasawara, Masayuki Yokode
Publikováno v:
Geriatrics & Gerontology International. 21:601-613
Background As Japan's population continues to age, it is estimated that the number of people aged ≥75 years will exceed 20 million by 2025. Furthermore, over the past 10 years, we have not reduced the difference between life expectancy and healthy
Autor:
Wirongrong Wongkitikamjorn, Jun Hosomichi, Eiji Wada, Hideyuki Maeda, Sirichom Satrawaha, Haixin Hong, Yukiko K Hayashi, Ken-ichi Yoshida, Takashi Ono
Publikováno v:
Cureus. 14(5)
Introduction Gestational intermittent hypoxia (IH), a hallmark of obstructive sleep apnea during gestation, alters respiratory neural control and diaphragm muscle contractile function in the offspring. The geniohyoid (GH) muscle is innervated by the
Autor:
Genri Kawahara, Yukiko K Hayashi
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165563 (2016)
SIL1 is a nucleotide exchange factor for the endoplasmic reticulum chaperone, BiP. Mutations in the SIL1 gene cause Marinesco-Sjögren syndrome (MSS), an autosomal recessive disease characterized by cerebellar ataxia, mental retardation, congenital c
Externí odkaz:
https://doaj.org/article/a006adf68a664f7e94b2a7f081dc97b3