Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Yukiko Imanishi"'
Autor:
Shigeru Miyagawa, Takuji Kawamura, Emiko Ito, Maki Takeda, Hiroko Iseoka, Junya Yokoyama, Akima Harada, Noriko Mochizuki-Oda, Yukiko Imanishi-Ochi, Junjun Li, Masao Sasai, Fumiyo Kitaoka, Masaki Nomura, Naoki Amano, Tomoko Takahashi, Hiromi Dohi, Eiichi Morii, Yoshiki Sawa
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Background Cell- or tissue-based regenerative therapy is an attractive approach to treat heart failure. A tissue patch that can safely and effectively repair damaged heart muscle would greatly improve outcomes for patients with heart failure
Externí odkaz:
https://doaj.org/article/dfacd8d29b3c4351b45788ad52a5a5a6
Autor:
Antti Siltanen, Kristo Nuutila, Yukiko Imanishi, Hisazumi Uenaka, Johanna Mäkelä, Tommi Pätilä, Antti Vento, Shigeru Miyagawa, Yoshiki Sawa, Ari Harjula, Esko Kankuri
Publikováno v:
Cell Transplantation, Vol 25 (2016)
Therapeutic effects of skeletal myoblast transplantation into the myocardium are mediated via paracrine factors. We investigated the ability of myoblast-derived soluble mediators to protect cardiomyocytes from oxidative stress. Fetal rat cardiac cell
Externí odkaz:
https://doaj.org/article/4f7bd7839b99441eb1a451669c19f46e
Autor:
Tommi Pätilä, Shigeru Miyagawa, Yukiko Imanishi, Satsuki Fukushima, Antti Siltanen, Eero Mervaala, Esko Kankuri, Ari Harjula, Yoshiki Sawa
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123963 (2015)
Although cell therapy of the failing heart by intramyocardial injections of myoblasts to results in regenerative benefit, it has also been associated with undesired and prospectively fatal arrhythmias. We hypothesized that intramyocardial injections
Externí odkaz:
https://doaj.org/article/77716bcb04b7479485e249f6c12e28c2
Autor:
Yukiko Imanishi, Shigeru Miyagawa, Satsuki Fukushima, Kazuhiko Ishimaru, Nagako Sougawa, Atsuhiro Saito, Yoshiki Sakai, Yoshiki Sawa
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69302 (2013)
BACKGROUND: A prostacyclin analogue, ONO-1301, is reported to upregulate beneficial proteins, including stromal cell derived factor-1 (SDF-1). We hypothesized that the sustained-release delivery of ONO-1301 would enhance SDF-1 expression in the acute
Externí odkaz:
https://doaj.org/article/8edcc6b5b59845f19694ffe2af0ccbce
Autor:
Shigeru, Miyagawa, Satoshi, Kainuma, Yukiko, Imanishi, Tomomi, Shimamoto, Yukako, Nitta, Chikako, Matsuo, Yasushi, Sakata, Masahiro, Takeuchi, Yoshiki, Sawa
Publikováno v:
Circulation Journal. 87:481-486
Clinical studies in regenerative medicine remain insufficient in Japan due to ethical concerns regarding the control group and a lack of statistical methodology to evaluate efficacy in a small treatment group. This study evaluated the efficacy of aut
Autor:
Tadashi Watabe, Yoshiki Sakai, Shigeru Miyagawa, Satsuki Fukushima, Yukiko Imanishi, Akima Harada, Hiroki Mizoguchi, Yoshiki Sawa
Publikováno v:
Journal of Artificial Organs. 24:465-472
Although prostacyclin is an endogenous factor for the protection and regeneration of damaged tissue, the use of clinically available prostacyclin analogues for treating chronic pathological conditions is limited owing to their short half-lives. A new
Autor:
Takuji Kawamura, Noriko Mochizuki-Oda, Shigeru Miyagawa, Satsuki Fukushima, Yoshiki Sawa, Yukiko Imanishi, Shigeo Masuda
Publikováno v:
Current Medicinal Chemistry
Advanced cardiac failure is a progressive intractable disease and is the main cause of mortality and morbidity worldwide. Since this pathology is represented by a definite decrease in cardiomyocyte number, supplementation of functional cardiomyocytes
Autor:
Atsuhiro Saito, Yukiko Imanishi, Hiroyuki Nishi, Taichi Sakaguchi, Shigeru Miyagawa, Yoshiki Sawa, Tatsuya Shimizu, Satsuki Fukushima, Hiroko Iseoka, Teruo Okano, Shunsuke Saito, Yasushi Yoshikawa
Publikováno v:
Transplantation. 93:1108-1115
Impairment of diastolic function and late remodeling are concerns after left ventricular restoration (LVR) for ischemic cardiomyopathy. This study aims to evaluate the effects of combined surgery of myoblast sheets (MS) implantation and LVR.Rat myoca
Autor:
Hidehiro Iida, Atsuhiro Saito, Takashi Yamauchi, Nariaki Matsuura, Yoshiki Sawa, Noboru Teramoto, Teruo Okano, Shigeru Miyagawa, Yukiko Imanishi, Tatsuya Shimizu, Yasushi Yoshikawa, Taichi Sakaguchi, Naomasa Kawaguchi
Publikováno v:
Transplantation. 90:364-372
BACKGROUND We hypothesized that autologous skeletal cell (SC) sheets regenerate the infract myocardium in porcine heart as a preclinical trial. METHODS AND RESULTS The impaired heart was created by implantation of ameroid constrictor on left anterior
Autor:
Yoshiki Sawa, Satoshi Taketani, Shigeru Miyagawa, Satoru Kitagawa-Sakakida, Yukiko Imanishi, Naosumi Sekiya
Publikováno v:
Journal of Artificial Organs. 12:187-193
To explore a new source of cell therapy for myocardial infarction (MI), we assessed the usefulness of mesenchymal stem cells derived from synovial membrane samples (SM MSCs). We developed a model of MI by ligation of the proximal left anterior descen