Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Yukiko Harima"'
Publikováno v:
Cell Reports, Vol 3, Iss 1, Pp 1-7 (2013)
Periodic somite segmentation is controlled by the cyclic gene Hes7, whose oscillatory expression depends upon negative feedback with a delayed timing. The mechanism that regulates the pace of segmentation remains to be determined, but mathematical mo
Externí odkaz:
https://doaj.org/article/e964d5dea10041e1abafb0489c82ffa2
Autor:
Fengzhu Xiong, Yukiko Harima, Tohru Ishitani, Masayuki Oginuma, Margarete Diaz-Cuadros, Oscar A. Tarazona, Olivier Pourquié, Arthur Michaut
Publikováno v:
Nature
Formation of the body of vertebrate embryos proceeds sequentially by posterior addition of tissues from the tail bud. Cells of the tail bud and the posterior presomitic mesoderm, which control posterior elongation1, exhibit a high level of aerobic gl
Publikováno v:
Genes & Development. 33:511-523
Somatic stem/progenitor cells are active in embryonic tissues but quiescent in many adult tissues. The detailed mechanisms that regulate active versus quiescent stem cell states are largely unknown. In active neural stem cells, Hes1 expression oscill
Publikováno v:
Seminars in Cell & Developmental Biology. 34:85-90
Somites, metameric structures, give rise to the vertebral column, ribs, skeletal muscles and subcutaneous tissues. In mouse embryos, a pair of somites is formed every 2h by segmentation of the anterior parts of the presomitic mesoderm. This periodic
Publikováno v:
IBRO Reports. 6:S20
Autor:
Fumiyoshi Ishidate, Hitoshi Miyachi, Takahiro K. Fujiwara, Kyogo Kawaguchi, Itaru Imayoshi, Akihiro Isomura, Ryoichiro Kageyama, Yukiko Harima, Hiroshi Kori
Publikováno v:
Science. 342:1203-1208
The basic-helix-loop-helix transcription factors Ascl1/Mash1, Hes1, and Olig2 regulate fate choice of neurons, astrocytes, and oligodendrocytes, respectively. These same factors are coexpressed by neural progenitor cells. Here, we found by time-lapse
Autor:
Yukiko Harima, Ryoichiro Kageyama
Publikováno v:
Current Opinion in Genetics & Development. 23:484-490
Somitogenesis is controlled by the segmentation clock, where the oscillatory expression of cyclic genes such as Hes7 leads to the periodic expression of Mesp2, a master gene for somite formation. Fgf signaling induces the oscillatory expression of He
Publikováno v:
Cell Reports, Vol 3, Iss 1, Pp 1-7 (2013)
Periodic somite segmentation is controlled by the cyclic gene Hes7, whose oscillatory expression depends upon negative feedback with a delayed timing. The mechanism that regulates the pace of segmentation remains to be determined, but mathematical mo
Publikováno v:
Wiley Interdisciplinary Reviews: Developmental Biology. 1:629-641
A bilateral pair of somites forms periodically by segmentation of the anterior ends of the presomitic mesoderm (PSM). This periodic event is regulated by a biological clock called the segmentation clock, which involves cyclic gene expression. Express
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1187
The Notch signaling effectors Hes1 and Hes7 exhibit oscillatory expression with a period of about 2-3 h during embryogenesis. Hes1 oscillation is important for proliferation and differentiation of neural stem cells, whereas Hes7 oscillation regulates