Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yukiko Chikazawa"'
Autor:
Takashi ONO, Katsutoshi YAMADA, Yukiko CHIKAZAWA, Masahiko UENO, Shozo NAKAMOTO, Takayuki OKUNO, Kaoru SENO
Publikováno v:
Biochemical Journal. 363:727-735
Cytosolic phospholipase A2α (cPLA2α), one of the three subtypes of cPLA2 (α, β and γ), is thought to be a rate-limiting enzyme in eicosanoid biosynthesis. We developed a novel and potent cPLA2α inhibitor with an optically active pyrrolidine, te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67d4ec071b2a7070621e26542d645954
https://doi.org/10.1042/bj3630727
https://doi.org/10.1042/bj3630727
Autor:
Masahiko Ueno, Takashi Ono, Masaaki Yamada, Toshihiko Okada, Yasushi Murakami, Toshiyuki Kato, Yukiko Chikazawa, Yuji Ito, Mitsuaki Ohtani, Sanji Hagishita, Isao Teshirogi, Takaharu Matsuura, Katsutoshi Yamada, Masaaki Wada, Kazuhiro Shirahase
Publikováno v:
Journal of Medicinal Chemistry. 39:3636-3658
Phospholipase A2 is an enzyme which hydrolyzes the sn-2 position of certain cellular phospholipids. The liberated lysophospholipid and arachidonic acid are precursors in the biosynthesis of various biologically active products. As human nonpancreatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8914f7eb81c1a540a3c20589d0fccf93
https://doi.org/10.1021/jm960395q
https://doi.org/10.1021/jm960395q
Autor:
Isao Teshirogi, Kazuhiro Shirahase, Takashi Ono, Masaaki Yamada, Yuji Ito, Masaaki Wada, Katsutoshi Yamada, Mitsuaki Ohtani, Toshihiko Okada, Yasushi Murakami, Takaharu Matsuura, Sanji Hagishita, Yukiko Chikazawa, Toshiyuki Kato, Masahiko Ueno
Publikováno v:
ChemInform. 28
Phospholipase A2 is an enzyme which hydrolyzes the sn-2 position of certain cellular phospholipids. The liberated lysophospholipid and arachidonic acid are precursors in the biosynthesis of various biologically active products. As human nonpancreatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d0f50ea6895d901ec6b1965f8c74230
https://doi.org/10.1002/chin.199703190
https://doi.org/10.1002/chin.199703190
Autor:
Takashi, Ono, Katsutoshi, Yamada, Yukiko, Chikazawa, Masahiko, Ueno, Shozo, Nakamoto, Takayuki, Okuno, Kaoru, Seno
Publikováno v:
The Biochemical journal. 363(Pt 3)
Cytosolic phospholipase A(2)alpha (cPLA(2)alpha), one of the three subtypes of cPLA(2) (alpha, beta and gamma), is thought to be a rate-limiting enzyme in eicosanoid biosynthesis. We developed a novel and potent cPLA(2)alpha inhibitor with an optical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2fc1fa159ace4a7688f8c580daa3a680
https://pubmed.ncbi.nlm.nih.gov/11964173
https://pubmed.ncbi.nlm.nih.gov/11964173
Autor:
Katsutoshi Yamada, Takaharu Matsuura, Sanji Hagishita, Shin-ichiro Hara, Isao Teshirogi, Koichi Nishi, Masahiko Ueno, Takashi Ono, Masaaki Yamada, Kaoru Seno, Tetsuo Okada, Yukiko Chikazawa, Makoto Kii, Takayuki Okuno, Mitsuaki Ohtani, Tomoyuki Ogawa, Yasuhiko Fujii, Fumihiko Watanabe, Shozo Nakamoto, Yasushi Murakami, Hiroshi Hashizume, Masaaki Wada
Publikováno v:
Journal of medicinal chemistry. 43(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7dec5b6dee013e74594fec77f9a2846
https://pubmed.ncbi.nlm.nih.gov/10737736
https://pubmed.ncbi.nlm.nih.gov/10737736
Autor:
Nobuhiro Maekawa, Makoto Shiga, Kahoru Nishina, Masaru Yoshinaga, Hidefumi Obara, Yozo Hori, Kenji Kuwabara, Yukiko Chikazawa, Katsuya Mikawa, Masahiko Ueno, Takashi Ono, Shingo Furue, Akihiro Matsukawa
Publikováno v:
American journal of respiratory and critical care medicine. 160(4)
Group IIA secretory phospholipase A(2) (sPLA(2)) has been implicated in a variety of inflammatory diseases including acute lung injury (ALI); however, the role of sPLA(2) in this disorder remains unclear. The aim of the present investigation was to e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44ee3c8d9908b5ff3e14e55a26df4ec4
https://pubmed.ncbi.nlm.nih.gov/10508821
https://pubmed.ncbi.nlm.nih.gov/10508821