Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Yukika Saga"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract It has been reported that autophagic activity is disturbed in the skeletal muscles of dystrophin-deficient mdx mice and patients with Duchenne muscular dystrophy (DMD). Transcriptional regulations of autophagy by FoxO transcription factors (
Externí odkaz:
https://doaj.org/article/11d7f1b891884e58bb08c3c4936a0559
Autor:
Ryusuke Hosoda, Ryuta Nakashima, Masaki Yano, Naotoshi Iwahara, Seidai Asakura, Iyori Nojima, Yukika Saga, Risa Kunimoto, Yoshiyuki Horio, Atsushi Kuno
Publikováno v:
Journal of Pharmacological Sciences, Vol 152, Iss 2, Pp 112-122 (2023)
Aging is associated with impairment of multiple organs, including skeletal muscle and heart. In this study, we investigated whether resveratrol, an activator of an NAD+-dependent protein deacetylase Sirtuin-1 (SIRT1), attenuates age-related sarcopeni
Externí odkaz:
https://doaj.org/article/93ecf3bf3956427989361595e6f9b9c4
Autor:
Atsushi Kuno, Ryusuke Hosoda, Miki Tsukamoto, Tatsuya Sato, Hiromi Sakuragi, Nami Ajima, Yukika Saga, Kouhei Tada, Yoshiki Taniguchi, Naotoshi Iwahara, Yoshiyuki Horio
Publikováno v:
Cardiovascular Research. 118:3360-3373
Cardiotoxicity by doxorubicin predicts worse prognosis of patients. Accumulation of damaged DNA has been implicated in doxorubicin-induced cardiotoxicity. SIRT1, an NAD+-dependent histone/protein deacetylase, protects cells by deacetylating target pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fed8afd39a184c7fc2d0167cb78bd0f0
https://doi.org/10.1093/cvr/cvac026
https://doi.org/10.1093/cvr/cvac026
Publikováno v:
Genes to cells : devoted to molecularcellular mechanismsREFERENCES.
STATa is a pivotal transcription factor for Dictyostelium development. dutA is the most abundant RNA transcribed by RNA polymerase II in Dictyostelium, and its functional interplay with STATa has been suggested. This study demonstrates that dutA RNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4916cc02dedd9eb9acfb40c733f35c65
https://pubmed.ncbi.nlm.nih.gov/36504347
https://pubmed.ncbi.nlm.nih.gov/36504347
Publikováno v:
Genes to Cells. 24:422-435
Dictyostelium STATa is a homologue of metazoan signal transducers and activators of transcription (STATs) and is important for morphogenesis. STATa is activated by phosphorylation on Tyr702 when cells are exposed to extracellular cAMP. Although two t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea07b19e59ebd38af683ba03532cc7c
https://doi.org/10.1111/gtc.12686
https://doi.org/10.1111/gtc.12686
Publikováno v:
Development, Growth & Differentiation. 58:383-399
STATa, a Dictyostelium homologue of metazoan signal transducer and activator of transcription, is important for the organizer function in the tip region of the migrating Dictyostelium slug. We previously showed that ecmF gene expression depends on ST
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d46a64bdd86f69ff5ffebfa34adc598b
https://doi.org/10.1111/dgd.12285
https://doi.org/10.1111/dgd.12285
Autor:
Nao Shimada, Takefumi Kawata, Yukika Saga, Yuri Nakamura, Yumi Iwade, Aya Sakurai, Megumi Ishikawa
Publikováno v:
SpringerPlus
Dictyostelium harbors multiple expansin-like genes with generally unknown functions. Thus, we analyzed the expansin-like 3 (expL3) gene and found that its expression was reduced in a null mutant for a STATa gene encoding a transcription factor. The e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04cb44086c0f04b4830395f946f9f390
http://europepmc.org/articles/PMC4408306
http://europepmc.org/articles/PMC4408306