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pro vyhledávání: '"Yukihiro Soutome"'
Autor:
Soichiro Hoshino, Ryohei Kanemura, Daisuke Kurita, Yukihiro Soutome, Hyouta Himeno, Masak Takaine, Masakatsu Watanabe, Nobukazu Nameki
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Hoshino et al. show that PTH3, the S. cerevisiae homolog of C12orf65, is required for the translation of mitochondrial genes in the presence of antibiotics. This study suggests that PTH3 rescues the ribosomes stalled by antibiotics, playing a role in
Externí odkaz:
https://doaj.org/article/00aad6f4ead54b9485ea6826cd9557f7
Autor:
Daisuke Kurita, Soichiro Hoshino, Nobukazu Nameki, Yukihiro Soutome, Ryohei Kanemura, Masakatsu Watanabe, Hyouta Himeno, Masak Takaine
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Mitochondrial translation appears to involve two stalled-ribosome rescue factors (srRFs). One srRF is an ICT1 protein from humans that rescues a “non-stop” type of mitochondrial ribosomes (mitoribosomes) stalled on mRNA lacking a stop codon, whil