Zobrazeno 1 - 10
of 303
pro vyhledávání: '"Yukihiro Nishiyama"'
Autor:
Gaku Takano, Shinichi Esaki, Fumi Goshima, Atsushi Enomoto, Yoshimi Hatano, Haruka Ozaki, Takahiro Watanabe, Yoshitaka Sato, Daisuke Kawakita, Shingo Murakami, Takayuki Murata, Yukihiro Nishiyama, Shinichi Iwasaki, Hiroshi Kimura
Publikováno v:
Molecular Therapy: Oncolytics, Vol 20, Iss , Pp 220-227 (2021)
Prognosis for advanced oral carcinoma remains poor. Oncolytic virotherapy uses replication-competent viruses to infect and kill only the tumor cells. However, it has been difficult to investigate the oncolytic activity of viruses against oral carcino
Externí odkaz:
https://doaj.org/article/d830ed6dd94a4d71905d92ea90a9657d
Autor:
Yoshitaka Sato, Takumi Kamura, Noriko Shirata, Takayuki Murata, Ayumi Kudoh, Satoko Iwahori, Sanae Nakayama, Hiroki Isomura, Yukihiro Nishiyama, Tatsuya Tsurumi
Publikováno v:
PLoS Pathogens, Vol 5, Iss 7, p e1000530 (2009)
p53-signaling is modulated by viruses to establish a host cellular environment advantageous for their propagation. The Epstein-Barr virus (EBV) lytic program induces phosphorylation of p53, which prevents interaction with MDM2. Here, we show that ind
Externí odkaz:
https://doaj.org/article/55b741061a9344278d7e34ddd52ff9e0
Autor:
Gaku Takano, Takayuki Murata, Hiroshi Kimura, Yukihiro Nishiyama, Hiromitsu Iwata, Takahiro Watanabe, Yoshimi Hatano, Kei Ijichi, Haruka Ozaki, Yuta Shibamoto, Shinichi Esaki, Fumi Goshima, Shingo Murakami, Daisuke Kawakita, Yoshitaka Sato
Publikováno v:
Cancer Gene Ther
Recent developments in therapeutic strategies have improved the prognosis of head and neck squamous cell carcinoma (HNSCC). Nevertheless, 5-year survival rate remains only 40%, necessitating new therapeutic agents. Oncolytic virotherapy entails use o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32df8f4a7039aa04877a2dfe7440a7be
https://doi.org/10.1038/s41417-019-0129-3
https://doi.org/10.1038/s41417-019-0129-3
Autor:
Yoshitaka Sato, Hiroshi Kimura, Gaku Takano, Shinichi Iwasaki, Yukihiro Nishiyama, Yoshimi Hatano, Shinichi Esaki, Haruka Ozaki, Takayuki Murata, Fumi Goshima, Atsushi Enomoto, Takahiro Watanabe, Shingo Murakami, Daisuke Kawakita
Publikováno v:
Molecular Therapy Oncolytics
Molecular Therapy: Oncolytics, Vol 20, Iss, Pp 220-227 (2021)
Molecular Therapy: Oncolytics, Vol 20, Iss, Pp 220-227 (2021)
Prognosis for advanced oral carcinoma remains poor. Oncolytic virotherapy uses replication-competent viruses to infect and kill only the tumor cells. However, it has been difficult to investigate the oncolytic activity of viruses against oral carcino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a032ff6de5173c23bb3ea3ab6de23266
https://pubmed.ncbi.nlm.nih.gov/33665360
https://pubmed.ncbi.nlm.nih.gov/33665360
Autor:
Rui, Tanaka, Fumi, Goshima, Shinichi, Esaki, Yoshitaka, Sato, Takayuki, Murata, Yukihiro, Nishiyama, Daisuke, Watanabe, Hiroshi, Kimura
Publikováno v:
American journal of cancer research. 7(8)
Advanced melanoma has long been treated with chemotherapy using cytotoxic agents like dacarbazine (DTIC), but overall survival rates with these drugs have been generally low. Recently, immunoregulatory monoclonal antibodies and molecularly targeted t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::18b8f6d9ae67991f15677686616e362e
https://pubmed.ncbi.nlm.nih.gov/28861325
https://pubmed.ncbi.nlm.nih.gov/28861325
Autor:
Fumi Goshima, Chenhong Luo, Hiroshi Kimura, Shinichi Esaki, Maki Kamakura, Yukihiro Nishiyama
Publikováno v:
International Journal of Cancer. 134:2865-2877
Ovarian cancer is the most frequent cause of gynecological cancer-related mortality as a majority of patients are diagnosed at an advanced stage with intraperitoneal dissemination because of the absence of initial symptoms. Granulocyte-macrophage col
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::204976e6af063c8af822f8776b2bd4f9
https://doi.org/10.1002/ijc.28631
https://doi.org/10.1002/ijc.28631
Autor:
Sumru Keceli, Koji Yamano, Shinichi Esaki, Fumi Goshima, Sachiyo Katsumi, Jun Kiguchi, Hiroshi Kimura, Hideyuki Okamoto, Shingo Murakami, Yukihiro Nishiyama
Publikováno v:
Otology & Neurotology. 33:1452-1457
Bell's palsy is highly associated with diabetes mellitus.The cause of Bell's palsy in diabetes mellitus is not completely understood. Diabetic mononeuropathy or reactivation of herpes simplex virus type 1 (HSV-1) may be responsible for the facial par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::452eb2f7f1d1b4729719f5916af6ac3a
https://doi.org/10.1097/mao.0b013e318268d54d
https://doi.org/10.1097/mao.0b013e318268d54d
Autor:
Tomohiro Kinoshita, Hiroshi Kimura, Seiji Kojima, Yoshinori Ito, Yukihiro Nishiyama, Kimikazu Matsumoto, Shinji Kawabe, Kensei Gotoh, Seiko Iwata
Publikováno v:
Cancer Sci
Epstein–Barr virus (EBV) infects various types of lymphocytes and is associated with not only B cell‐origin lymphoma, but also T or natural killer cell lymphoproliferative diseases (T/NK LPD). Recently, we established a novel assay to identify EB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ce85f2fef3bce09ac9ab54d7148c406
https://doi.org/10.1111/j.1349-7006.2012.02305.x
https://doi.org/10.1111/j.1349-7006.2012.02305.x
Autor:
Masaru Ihira, Ken Sugata, Tetsushi Yoshikawa, Akane Ohta, Yukihiro Nishiyama, Yuki Higashimoto, Dharam V. Ablashi, Daniel L. Peterson, Paolo Lusso, Yoshizo Asano
Publikováno v:
Journal of Clinical Microbiology. 50:1245-1251
In order to assess the full spectrum of human herpesvirus 6A (HHV-6A)- and HHV-6B-associated diseases, we sought to develop an HHV-6 species-specific serological assay based on immunoblot analysis. The immunodominant proteins encoded by open reading
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baf510845c1e53c080bbe99a70f4d1cb
https://doi.org/10.1128/jcm.05834-11
https://doi.org/10.1128/jcm.05834-11
Autor:
Yukihiro Nishiyama, Yohei Yamauchi, Fumi Goshima, Hiroshi Kimura, Tsugiya Murayama, Maki Kamakura, Zhuan Li
Publikováno v:
Journal of Virology. 86:492-503
Tankyrase 1 is a poly(ADP-ribose) polymerase (PARP) which localizes to multiple subcellular sites, including telomeres and mitotic centrosomes. Poly(ADP-ribosyl)ation of the nuclear mitotic apparatus (NuMA) protein by tankyrase 1 during mitosis is es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8ba9d5e6ee9e7f563cc204bb90a22d0
https://doi.org/10.1128/jvi.05897-11
https://doi.org/10.1128/jvi.05897-11