Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Yukihiro Isogai"'
Autor:
Hiroki Oba, Jun Takahashi, Yosuke Shibata, Tetsuro Ohba, Tomohiko Hasegawa, Yukihiro Isogai, Shugo Kuraishi, Shota Ikegami, Masashi Uehara, Takashi Takizawa, Ryo Munakata, Terue Hatakenaka, Toshiyuki Ojima, Zentaro Yamagata, Yukihiro Matsuyama, Hirotaka Haro
Publikováno v:
Spine Surgery and Related Research, Vol 6, Iss 1, Pp 63-70 (2022)
Introduction: Assessments of early postoperative bony union after posterior lumbar interbody fusion via computed tomography (CT) have revealed cases in which interbody fixation by bony union resulted in nonfusion due to bone absorption. The apparent
Externí odkaz:
https://doaj.org/article/19ae5e79acd34dc0a9ff22534bed84dd
Enhancement of ghrelin-signaling system by Rikkunshi-To attenuates teriparatide-induced pica in rats
Publikováno v:
Journal of Pharmacological Sciences, Vol 137, Iss 2, Pp 137-145 (2018)
Teriparatide is clinically used for the treatment of osteoporosis; however, nausea is often observed in patients. Its insufficient control affects the ability to continue teriparatide therapy. Rikkunshi-To (RKT), a traditional Japanese herbal medicin
Externí odkaz:
https://doaj.org/article/df3b89f79fdf4e4da93b09de3e0386cf
Autor:
Masayuki Furuya, Junichi Kikuta, Sayumi Fujimori, Shigeto Seno, Hiroki Maeda, Mai Shirazaki, Maki Uenaka, Hiroki Mizuno, Yoriko Iwamoto, Akito Morimoto, Kunihiko Hashimoto, Takeshi Ito, Yukihiro Isogai, Masafumi Kashii, Takashi Kaito, Shinsuke Ohba, Ung-il Chung, Alexander C. Lichtler, Kazuya Kikuchi, Hideo Matsuda, Hideki Yoshikawa, Masaru Ishii
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Communication between osteoblasts and osteoclasts is essential for bone homeostasis, but the mode of interaction is unclear. The authors use intravital two-photon microscopy in mice to show that these cells directly interact, regulating activity of o
Externí odkaz:
https://doaj.org/article/06c00b6672ba4168b243c12ea9e27007
Autor:
Hiroshi Yamane, Aya Takakura, Yukari Shimadzu, Toshiyuki Kodama, Ji-Won Lee, Yukihiro Isogai, Toshinori Ishizuya, Ryoko Takao-Kawabata, Tadahiro Iimura
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175329 (2017)
Teriparatide [human parathyroid hormone (1-34)], which exerts an anabolic effect on bone, is used for the treatment of osteoporosis in patients who are at a high risk for fracture. That the once-daily administration of teriparatide causes an increase
Externí odkaz:
https://doaj.org/article/ce76b8f576634e3ba4a9e32f3a880dd1
Autor:
Yasuhiro Kobayashi, Koichi Matsuo, Naoyuki Takahashi, Toru Hiraga, Ryoko Takao-Kawabata, Nobuyuki Udagawa, Atsushi Arai, Akira Yamaguchi, Toshinori Ishizuya, Toshihisa Komori, Mengyu Yang, Yukihiro Isogai, Kohei Murakami, Toshihide Mizoguchi, Lijuan Zhao, Daisuke Nishida
Publikováno v:
Journal of Bone and Mineral Research. 34:1952-1963
Intermittent parathyroid hormone (iPTH) treatment induces bone anabolic effects that result in the recovery of osteoporotic bone loss. Human PTH is usually given to osteoporotic patients because it induces osteoblastogenesis. However, the mechanism b
Autor:
Momoko Nakatsugawa, Hirotoshi Utsunomiya, Akihiko Tokuda, Aya Takakura, Yukihiro Isogai, Misa Nakamura, Ryoko Takao-Kawabata, Ryohei Kono, Akihiro Maeno, Toshinori Ishizuya, Akihiro Kitami, Sachiko Nomura
Publikováno v:
Endocrinology
Osteoporosis is a complication of diabetes mellitus (DM). The pathology of diabetic osteoporosis is distinct from postmenopausal osteoporosis, and there are no specific treatment guidelines for diabetic osteoporosis. In the current study, this issue
Autor:
Hiroki Ushirozako, Yukihiro Isogai, Toshiyuki Ojima, Eisaku Okada, Jun Takahashi, Yukihiro Matsuyama, Tomohiko Hasegawa, Shigeto Ebata, Hirotaka Haro, Hiroki Oba, Keijiro Mukaiyama, Tetsuro Ohba
Publikováno v:
Spine. 44(5)
A multicenter case-control study.The aim of this study was to investigate the independent predictors of osseous union after posterior lumbar interbody fusion (PLIF).PLIF is usually performed to treat lumbar degenerative diseases in elderly patients.
Autor:
Yoriko Iwamoto, Hideo Matsuda, Junichi Kikuta, Sayumi Fujimori, Yukihiro Isogai, Mai Shirazaki, Shinsuke Ohba, Kunihiko Hashimoto, Masaru Ishii, Alexander C. Lichtler, Hiroki Mizuno, Shigeto Seno, Masayuki Furuya, Takeshi Ito, Hiroki Maeda, Ung-il Chung, Maki Uenaka, Hideki Yoshikawa, Kazuya Kikuchi, Masafumi Kashii, Takashi Kaito, Akito Morimoto
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Bone homeostasis is regulated by communication between bone-forming mature osteoblasts (mOBs) and bone-resorptive mature osteoclasts (mOCs). However, the spatial–temporal relationship and mode of interaction in vivo remain elusive. Here we show, by
Autor:
Tatsuhiko Kuroda, Kouichi Yamamoto, Atsushi Yamatodani, Naoto Kato, Takayuki Ishida, Yukihiro Isogai
Publikováno v:
European Journal of Pharmacology. 764:457-462
Intermittent subcutaneous injection of teriparatide, an active fragment of human parathyroid hormone, is clinically used for the treatment of osteoporosis. Patients suffer from nausea, which is one of the side effects teriparatide induces; however, t
Autor:
Hiroshi Kuriyama, Emika Sugimoto, Yukihiro Isogai, Toshinori Ishizuya, Aya Takakura, Ryoko Takao-Kawabata, Ichiro Ikegaki, Osamu Nakazono
Publikováno v:
Calcified Tissue International
Intermittent repeated administration of teriparatide (TPTD) has potent anabolic effects on bones in vivo. However, TPTD has both anabolic and catabolic effects on osteoblasts in vitro, and the mechanisms underlying its promotion of bone formation are