Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Yukihiko Sugita"'
Autor:
Dohyun Im, Jun-ichi Kishikawa, Yuki Shiimura, Hiromi Hisano, Akane Ito, Yoko Fujita-Fujiharu, Yukihiko Sugita, Takeshi Noda, Takayuki Kato, Hidetsugu Asada, So Iwata
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Histamine is a biogenic amine that participates in allergic and inflammatory processes by stimulating histamine receptors. The histamine H4 receptor (H4R) is a potential therapeutic target for chronic inflammatory diseases such as asthma and
Externí odkaz:
https://doaj.org/article/aecb7ce92dad48079fb1d6b2c25e5659
Autor:
Yoko Fujita-Fujiharu, Yukihiko Sugita, Yuki Takamatsu, Kazuya Houri, Manabu Igarashi, Yukiko Muramoto, Masahiro Nakano, Yugo Tsunoda, Ichiro Taniguchi, Stephan Becker, Takeshi Noda
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Marburg virus causes severe hemorrhagic fever in humans. Here, the authors determine the structure of Marburg virus nucleoprotein–RNA complex by cryo-electron microscopy and provide mechanistic insight into the helical assembly of the nucleocapsid.
Externí odkaz:
https://doaj.org/article/3bb5abd022ad48579c8ac63fd0191e66
Autor:
Masahiro Nakano, Yukihiko Sugita, Noriyuki Kodera, Sho Miyamoto, Yukiko Muramoto, Matthias Wolf, Takeshi Noda
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Nakano et al. use high-speed AFM and cryo-EM to study influenza virus RNA synthesis in vitro. They observe the synthesis of two types of RNA: folded single stranded RNA associated to an intact viral ribonucleoprotein (vRNP) and looped, double strande
Externí odkaz:
https://doaj.org/article/3053430dbc224e4ebb0c95d84cad59fc
Autor:
Si-Si Liu, Fei Jin, Yi-Shi Liu, Yoshiko Murakami, Yukihiko Sugita, Takayuki Kato, Xiao-Dong Gao, Taroh Kinoshita, Motoyuki Hattori, Morihisa Fujita
Publikováno v:
Molecules, Vol 26, Iss 18, p 5462 (2021)
Glycosylphosphatidylinositol (GPI) anchor modification is a posttranslational modification of proteins that has been conserved in eukaryotes. The biosynthesis and transfer of GPI to proteins are carried out in the endoplasmic reticulum. Attachment of
Externí odkaz:
https://doaj.org/article/1243bbe3a95b4aab90632b9f330bf8b5
Autor:
Shangfan Hu, Yoko Fujita-Fujiharu, Yukihiko Sugita, Lisa Wendt, Yukiko Muramoto, Masahiro Nakano, Thomas Hoenen, Takeshi Noda
Publikováno v:
PNAS Nexus. 2
Lloviu virus (LLOV) is a novel filovirus detected in Schreiber’s bats in Europe. The isolation of the infectious LLOV from bats has raised public health concerns. However, the virological and molecular characteristics of LLOV remain largely unknown
Autor:
Ryoji, Suno, Yukihiko, Sugita, Kazushi, Morimoto, Hiroko, Takazaki, Hirokazu, Tsujimoto, Mika, Hirose, Chiyo, Suno-Ikeda, Norimichi, Nomura, Tomoya, Hino, Asuka, Inoue, Kenji, Iwasaki, Takayuki, Kato, So, Iwata, Takuya, Kobayashi
Publikováno v:
Cell reports. 40(11)
Prostaglandin receptors have been implicated in a wide range of functions, including inflammation, immune response, reproduction, and cancer. Our group has previously determined the crystal structure of the active-like EP3 bound to its endogenous ago
Autor:
Yoko Fujita-Fujiharu, Yukihiko Sugita, Yuki Takamatsu, Kazuya Houri, Manabu Igarashi, Yukiko Muramoto, Masahiro Nakano, Yugo Tsunoda, Ichiro Taniguchi, Stephan Becker, Takeshi Noda
Publikováno v:
Nature communications. 13(1)
The nucleoprotein (NP) of Marburg virus (MARV), a close relative of Ebola virus (EBOV), encapsidates the single-stranded, negative-sense viral genomic RNA (vRNA) to form the helical NP–RNA complex. The NP–RNA complex constitutes the core structur
Autor:
Fei Jin, Motoyuki Hattori, Yi-Shi Liu, Yukihiko Sugita, Takayuki Kato, Yoshiko Murakami, Morihisa Fujita, Si-Si Liu, Xiao-Dong Gao, Taroh Kinoshita
Publikováno v:
Molecules
Volume 26
Issue 18
Molecules, Vol 26, Iss 5462, p 5462 (2021)
Volume 26
Issue 18
Molecules, Vol 26, Iss 5462, p 5462 (2021)
Glycosylphosphatidylinositol (GPI) anchor modification is a posttranslational modification of proteins that has been conserved in eukaryotes. The biosynthesis and transfer of GPI to proteins are carried out in the endoplasmic reticulum. Attachment of
Autor:
Masahiro Nakano, Yoko Fujita-Fujiharu, Yugo Tsunoda, Yukiko Muramoto, Kazuya Houri, Yukihiko Sugita, Yuki Takamatsu, Stephan Becker, Takeshi Noda, Manabu Igarashi
The nucleoprotein (NP) of Marburg virus (MARV), a close relative of Ebola virus (EBOV), encapsidates the single-stranded, negative-sense viral genomic RNA (vRNA) to form the helical NP-RNA complex. The NP-RNA complex serves as a scaffold for the asse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::606a8beffef02b46d6ef634bd944bf17
https://doi.org/10.1101/2021.07.13.452116
https://doi.org/10.1101/2021.07.13.452116
Autor:
Takeshi Noda, Yukiko Muramoto, Sho Miyamoto, Noriyuki Kodera, Matthias Wolf, Masahiro Nakano, Yukihiko Sugita
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Communications Biology
Communications Biology
The single-stranded, negative-sense, viral genomic RNA (vRNA) of influenza A virus is encapsidated by viral nucleoproteins (NPs) and an RNA polymerase to form a ribonucleoprotein complex (vRNP) with a helical, rod-shaped structure. The vRNP is respon