Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Yukihiko Shirayama"'
Autor:
Ji-chun Zhang, Wei Yao, Youge Qu, Mayumi Nakamura, Chao Dong, Chun Yang, Qian Ren, Min Ma, Mei Han, Yukihiko Shirayama, Akiko Hayashi-Takagi, Kenji Hashimoto
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-4 (2023)
Externí odkaz:
https://doaj.org/article/620dec1f3a5f4e33ada6cb176524d32d
Autor:
Yukihiko Shirayama, Kazuki Matsumoto, Sayo Hamatani, Katsumasa Muneoka, Akihiro Okada, Koichi Sato
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Reported empathy deficits in autism spectrum disorder (ASD) could be attributable to other ASD-related features. We evaluated 28 ASD adults with no intellectual disability and 24 age-matched non-ASD control subjects using the Autism-Spectrum
Externí odkaz:
https://doaj.org/article/737d5e42789d452b845c5fb85284c2d4
Autor:
Tsuyoshi Nishiguchi, Masaaki Iwata, Naofumi Kajitani, Akihiko Miura, Ryoichi Matsuo, Shumei Murakami, Yumeto Nakada, Shenghong Pu, Yuki Shimizu, Tatsuya Tsubakino, Takehiko Yamanashi, Gen Shinozaki, Jun Tsubota, Yukihiko Shirayama, Ken Watanabe, Koichi Kaneko
Publikováno v:
Neuropsychopharmacology Reports, Vol 41, Iss 2, Pp 159-167 (2021)
Abstract Aim This study aimed to assess the response of endogenous beta‐hydroxybutyrate to psychological stress, and its association with nucleotide‐binding domain, leucine‐rich repeat, pyrin domain‐containing 3 (NLRP3) inflammasome, and stre
Externí odkaz:
https://doaj.org/article/89a507868d4c47d0b7e8972fbf36f2a7
Autor:
Takehiko Yamanashi, Masaaki Iwata, Midori Shibushita, Kyohei Tsunetomi, Mayu Nagata, Naofumi Kajitani, Akihiko Miura, Ryoichi Matsuo, Tsuyoshi Nishiguchi, Takahiro A. Kato, Daiki Setoyama, Yukihiko Shirayama, Ken Watanabe, Gen Shinozaki, Koichi Kaneko
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Abstract Accumulating evidence suggests that elevated inflammation contributes to the pathophysiology of post-traumatic stress disorder (PTSD) and that anti-inflammatory drugs might be a new treatment strategy for PTSD. It has been reported that beta
Externí odkaz:
https://doaj.org/article/cc4db5e18bf94e68b1156751f8c6a098
Autor:
Naofumi Kajitani, Masaaki Iwata, Akihiko Miura, Kyohei Tsunetomi, Takehiko Yamanashi, Ryoichi Matsuo, Tsuyoshi Nishiguchi, Saki Fukuda, Mayu Nagata, Midori Shibushita, Takahira Yamauchi, Shenghong Pu, Yukihiko Shirayama, Ken Watanabe, Koichi Kaneko
Publikováno v:
Neuropsychopharmacology Reports, Vol 40, Iss 2, Pp 157-165 (2020)
Abstract Aims Neuroinflammation is deeply related to the pathophysiology of depression. Beta‐hydroxybutyrate (BHB), which is an endogenous ketone body, exerts anti‐inflammatory effects, and peripheral administration of BHB induces antidepressant
Externí odkaz:
https://doaj.org/article/1dc2ae56613c4f00b1ead9cd722fbd80
Publikováno v:
BMC Psychology, Vol 7, Iss 1, Pp 1-14 (2019)
Abstract Background Clinical anxiety is common during the perinatal period, and anxiety symptoms often persist after childbirth. Ten to 30 % of perinatal women are diagnosed with panic disorder (PD)—far more than the 1.5–3% rate among the general
Externí odkaz:
https://doaj.org/article/96e49fa0eba9472395e7e984dba3d405
Autor:
Ji-chun Zhang, Wei Yao, Youge Qu, Mayumi Nakamura, Chao Dong, Chun Yang, Qian Ren, Min Ma, Mei Han, Yukihiko Shirayama, Akiko Hayashi-Takagi, Kenji Hashimoto
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Accumulating evidence suggests a role of the ephrin receptor EphA4 and the downstream protein ephexin1 in synaptic plasticity, which is implicated in depression. We examined whether EphA4–ephexin1 signaling plays a role in the pathophysiol
Externí odkaz:
https://doaj.org/article/0f45d7fbf32c4ae391afa79a31346e94
Autor:
Takehiko Yamanashi, Masaaki Iwata, Naho Kamiya, Kyohei Tsunetomi, Naofumi Kajitani, Nodoka Wada, Takahiro Iitsuka, Takahira Yamauchi, Akihiko Miura, Shenghong Pu, Yukihiko Shirayama, Ken Watanabe, Ronald S. Duman, Koichi Kaneko
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Neuro-inflammation has been shown to play a critical role in the development of depression. Beta-hydroxybutyrate (BHB) is a ketone body and has recently been reported to exert anti-inflammatory effects via inhibition of NLRP3 inflammasome. H
Externí odkaz:
https://doaj.org/article/7a47716c1b5542f2802d09eae4f2cab7
Autor:
Masatoshi Suzuki, Michio Takahashi, Katsumasa Muneoka, Koichi Sato, Kenji Hashimoto, Yukihiko Shirayama
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109137 (2014)
The psychological aspects of treatment-resistant and remitted depression are not well documented.We administered the Minnesota Multiphasic Personality Inventory (MMPI) to patients with treatment-resistant depression (n = 34), remitted depression (n =
Externí odkaz:
https://doaj.org/article/160edf04a6a440f8822cb9a3ce8b6ab9
Autor:
Michio Takahashi, Yukihiko Shirayama, Katsumasa Muneoka, Masatoshi Suzuki, Koichi Sato, Kenji Hashimoto
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e71964 (2013)
BackgroundRecently, we reported that low reward dependence, and to a lesser extent, low cooperativeness in the Temperature and Character Inventory (TCI) may be risk factors for treatment-resistant depression. Here, we analyzed additional psychologica
Externí odkaz:
https://doaj.org/article/e4332b6fc6544d82a5c367574b9e660c