Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Yukihiko Nishizawa"'
Autor:
Kentaro Minami, Yoshinari Shinsato, Masatatsu Yamamoto, Homare Takahashi, Shaoxuan Zhang, Yukihiko Nishizawa, Sho Tabata, Ryuji Ikeda, Kohich Kawahara, Kazutake Tsujikawa, Kazuo Chijiiwa, Katsushi Yamada, Shin-ichi Akiyama, Sandra Pérez-Torras, Marcal Pastor-Anglada, Tatsuhiko Furukawa, Takeda Yasuo
Publikováno v:
Journal of Pharmacological Sciences, Vol 127, Iss 3, Pp 319-325 (2015)
Gemcitabine is widely used for pancreatic, lung, and bladder cancer. However, drug resistance against gemcitabine is a large obstacle to effective chemotherapy. Nucleoside transporters, nucleoside and nucleotide metabolic enzymes, and efflux transpor
Externí odkaz:
https://doaj.org/article/e28f81e30aca46799f20a3a01b38934e
Autor:
Mina Nitta, Ryuji Ikeda, Tatsuhiko Furukawa, Yasuo Takeda, Kentaro Minami, Masatatsu Yamamoto, Yoshinari Shinsato, Kohichi Kawahara, Yukihiko Nishizawa, Shin-ichi Akiyama, Hideyuki Terazono
Publikováno v:
Anticancer Research. 39:4129-4136
Background/aim 5-Aza-2-deoxycytidine (5-Aza-CdR) enhances the sensitivity to 5-fluorouracil (5-FU), but the molecular mechanism is not fully understood. The aim of this study was to investigate the molecular mechanism that enhances the sensitivity to
Autor:
Yusuke Tajitsu, Yukihiko Nishizawa, Shogo Masuda, Yasuo Takeda, Ryuji Ikeda, Nariaki Tomiyama
Publikováno v:
Oncology Letters.
Cancer stem-like cells (CSCs), which possess the ability to self-renewal and are multipotent, are regarded as the cause of tumor formation, recurrence, metastasis and drug resistance. It is necessary to understand the properties of CSCs in order to t
Autor:
Akihide Tanimoto, Tomoko Fukushige, Hiroshi Arimura, Kentarou Minami, Masatatsu Yamamoto, Tatsuhiko Furukawa, Yukihiko Nishizawa, Shin-ichi Akiyama, Masayuki Nakagawa, Takuro Kanekura
Publikováno v:
Molecular and Cellular Biology. 34:1077-1084
Abcb10, member 10 of the ABC transporter family, is reportedly a part of a complex in the mitochondrial inner membrane with mitoferrin-1 (Slc25a37) and ferrochelatase (Fech) and is responsible for heme biosynthesis in utero. However, it is unclear wh
Autor:
Yoshinari Shinsato, Kazunori Arita, Hajime Yonezawa, Kohichi Kawahara, Hirofumi Hirano, Yukihiko Nishizawa, Hiroshi Tokimura, Masatatsu Yamamoto, Ryuji Ikeda, Shunji Yunoue, Tatsuhiko Furukawa, Kentarou Minami
Publikováno v:
Oncotarget
Although there is a relationship between DNA repair deficiency and temozolomide (TMZ) resistance in glioblastoma (GBM), it remains unclear which molecule is associated with GBM recurrence. We isolated three TMZ-resistant human GBM cell lines and exam
Autor:
Shin-ichi Akiyama, Tomoyuki Sumizawa, Masatatsu Yamamoto, Sho Tabata, Mina Nitta, Yasuo Takeda, Tatsuhiko Furukawa, Tatsuya Yamaguchi, Yukihiko Nishizawa, Xiao-Fang Che, Hirofumi Mataki, Katsushi Yamada, Yusuke Tajitsu, Ryuji Ikeda
Publikováno v:
International Journal of Molecular Medicine. 32:703-708
Major vault protein (MVP) is identical to lung resistance-related protein (LRP), which is the major component of vaults. Vaults are considered to play a protective role against xenobiotics and other types of stress. In a previous study, we reported t
Autor:
Tatsuhiko Furukawa, Masatatsu Yamamoto, Ryuji Ikeda, Yusuke Tajitsu, Yasuo Takeda, Sho Tabata, Katsushi Yamada, Yoshinari Shinsato, Yukihiko Nishizawa, Kentaro Minami, Shin-ichi Akiyama
Publikováno v:
Oncology Reports. 30:1444-1448
The angiogenic factor, platelet-derived endothelial cell growth factor/thymidine phosphorylase (PD-ECGF/TP), stimulates the chemotaxis of endothelial cells and confers resistance to apoptosis induced by hypoxia. 2-Deoxy-D-ribose, a degradation produc
Autor:
Yukihiko, Nishizawa
Publikováno v:
フェリス女学院大学音楽学部紀要. :15-26
Autor:
Kentaro, Minami, Youhei, Kamijo, Yukihiko, Nishizawa, Sho, Tabata, Fumito, Horikuchi, Masatatsu, Yamamoto, Kohich, Kawahara, Yoshinari, Shinsato, Tokushi, Tachiwada, Zhe-Sheng, Chen, Kazutake, Tsujikawa, Masayuki, Nakagawa, Naohiko, Seki, Shin-Ichi, Akiyama, Kazunari, Arima, Yasuo, Takeda, Tatsuhiko, Furukawa
Publikováno v:
Anticancer research. 34(9)
A previously established arsenite-resistant cell line, KAS, is also resistant to a variety of anticancer drugs. In order to understand responsible molecules for the multidrug resistance phenotype of KAS cells, we examined the expressions of ATP-bindi
Autor:
Shin-ichi Akiyama, Tatsuhiko Furukawa, Yasuo Takeda, Shogo Masuda, Ryuji Ikeda, Hironori Mataki, Yusuke Tajitsu, Kentaro Minami, Yukihiko Nishizawa, Katsushi Yamada
Publikováno v:
Oncology reports. 31(1)
Major vault protein (MVP) is the main constituent of the vault ribonucleoprotein particle and is identical to lung resistance-related protein (LRP). Although MVP is also expressed in several types of normal tissues, little is known about its physiolo