Zobrazeno 1 - 10
of 269
pro vyhledávání: '"Yukihiko Hiroshima"'
Autor:
Soji Toda, Hiroyuki Iwasaki, Yoichiro Okubo, Hiroyuki Hayashi, Mei Kadoya, Hiroyuki Takahashi, Tomoyuki Yokose, Yukihiko Hiroshima, Katsuhiko Masudo
Publikováno v:
Endocrine Journal, Vol 71, Iss 1, Pp 31-37 (2023)
We analyzed the outcomes of genetic testing to study the frequency of mutations in advanced thyroid cancer in Japan. Patients (n = 96) with unresectable or metastatic thyroid carcinoma were included for retrospective chart review. Results of gene pan
Externí odkaz:
https://doaj.org/article/8937867933924636a22abe4e8c218fd9
Autor:
Chie Hasegawa, Kota Washimi, Yukihiko Hiroshima, Rika Kasajima, Keiji Kikuchi, Tsuguto Notomi, Hisamori Kato, Toru Hiruma, Shinya Sato, Yoichiro Okubo, Emi Yoshioka, Kyoko Ono, Yohei Miyagi, Tomoyuki Yokose
Publikováno v:
Diagnostic Pathology, Vol 18, Iss 1, Pp 1-7 (2023)
Abstract Background Uterine adenosarcoma is a rare malignant tumor that accounts for 8% of all uterine sarcomas, and less than 0.2% of all uterine malignancies. However, it is frequently misdiagnosed in clinical examinations, including pathological d
Externí odkaz:
https://doaj.org/article/2fee853fce144e138814f5c09bf4e4d1
Autor:
Mizuha Haraguchi Hashiguchi, Takashi Sato, Rinako Watanabe, Junko Kagyo, Tomohiko Matsuzaki, Hideharu Domoto, Terufumi Kato, Yoshiro Nakahara, Tomoyuki Yokose, Yukihiko Hiroshima, Tetsuya Shiomi
Publikováno v:
Thoracic Cancer, Vol 12, Iss 18, Pp 2504-2507 (2021)
Abstract ROS1 rearrangements are found in 1–2% of patients with non‐small‐cell lung cancer. The detection of the rearrangements is crucial since clinically effective molecular targeted drugs are available for them. We present a case of lung ade
Externí odkaz:
https://doaj.org/article/01a8a868f9964bc7872077c784ae4a48
Autor:
Suguru Nukada, Yoichiro Okubo, Manabu Shiozawa, Emi Yoshioka, Masaki Suzuki, Kota Washimi, Kae Kawachi, Sumito Sato, Yukihiko Hiroshima, Yasushi Rino, Tomoyuki Yokose, Munetaka Masuda
Publikováno v:
Journal of the Anus, Rectum and Colon, Vol 5, Iss 2, Pp 167-172 (2021)
Objectives: Molecular profiling of marker mutations has become an essential aspect in the treatment planning for colorectal cancer (CRC). Anaplastic lymphoma kinase (ALK) mutations could be used as markers in CRC molecular profiling. However, the ext
Externí odkaz:
https://doaj.org/article/2c38898a7c5d4bbb9da8a0a044883f14
Autor:
Itaru Hashimoto, Yayoi Kimura, Naohide Oue, Yukihiko Hiroshima, Toru Aoyama, Yasushi Rino, Tomoyuki Yokose, Wataru Yasui, Yohei Miyagi, Takashi Oshima
Publikováno v:
Cancers, Vol 14, Iss 18, p 4427 (2022)
Background: We sought to identify an optimal combination of survival risk stratification markers in patients with pathological (p) stage II/III gastric cancer (GC) after curative resection. Methods: We measured the expression levels of 127 genes in p
Externí odkaz:
https://doaj.org/article/7856da32b7ee45cbb584b98afba32fda
Autor:
Daisuke Kawaguchi, Yukihiko Hiroshima, Takafumi Kumamoto, Ryutaro Mori, Ryusei Matsuyama, Yasushi Ichikawa, Yoshiaki Inayama, Itaru Endo
Publikováno v:
Annals of Hepatology, Vol 18, Iss 1, Pp 89-100 (2019)
Introduction and aim. We developed a rat model of portal vein ligation (PVL) with venous congestion (PVL+C) to investigate beneficial effect PVL plus congestion for regeneration of intact liver segments.Materials and methods. In the PVL group, portal
Externí odkaz:
https://doaj.org/article/efeef082d38345338904d102d6b0d9cb
Autor:
Keiichi Yazawa, Fumio Nakamura, Daiki Masukawa, Sho Sato, Yukihiko Hiroshima, Yasuhiro Yabushita, Ryutaro Mori, Ryusei Matsuyama, Ikuma Kato, Hideki Taniguchi, Yoshio Goshima, Itaru Endo
Publikováno v:
Translational Oncology, Vol 13, Iss 3, Pp - (2020)
Pancreatic intraepithelial neoplasia (PanIN), the most common premalignant lesion of the pancreas, is a histologically well-defined precursor to invasive pancreatic ductal adenocarcinoma (PDAC). However, the molecular mechanisms underlying the progre
Externí odkaz:
https://doaj.org/article/0e1ffe5d2cd1447d8abdf173a9c71bca
Autor:
Kentaro Miyake, Takashi Higuchi, Hiromichi Oshiro, Zhiying Zhang, Norihiko Sugisawa, Jun Ho Park, Sahar Razmjooei, Yuki Katsuya, Maryam Barangi, Yunfeng Li, Scott D. Nelson, Takashi Murakami, Yuki Homma, Yukihiko Hiroshima, Ryusei Matsuyama, Michael Bouvet, Sant P. Chawla, Shree Ram Singh, Itaru Endo, Robert M. Hoffman
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 117, Iss , Pp - (2019)
Liposarcoma (LS) is a chemotherapy-resistant disease. The aim of the present study was to find precise therapy for a recurrent dedifferentiated liposarcoma (DDLS) in a patient-derived orthotopic xenograft (PDOX) model. The DDLS PDOX models were estab
Externí odkaz:
https://doaj.org/article/71f048f7abf14fbfb7b32e8006cc37ea
Autor:
Kentaro Miyake, Kei Kawaguchi, Masuyo Miyake, Ming Zhao, Tasuku Kiyuna, Kentaro Igarashi, Zhiying Zhang, Takashi Murakami, Yunfeng Li, Scott D. Nelson, Michael Bouvet, Irmina Elliott, Tara A. Russell, Arun S. Singh, Yukihiko Hiroshima, Masashi Momiyama, Ryusei Matsuyama, Takashi Chishima, Shree Ram Singh, Itaru Endo, Fritz C. Eilber, Robert M. Hoffman
Publikováno v:
Heliyon, Vol 4, Iss 6, Pp e00643- (2018)
Gastrointestinal stromal tumor (GIST) is a refractory disease in need of novel efficacious therapy. The aim of our study was to evaluate the effectiveness of tumor-targeting Salmonella typhimurium A1-R (S. typhimurium A1-R) using on a patient derived
Externí odkaz:
https://doaj.org/article/a10b0dc2ca8c4a67a22ab4000f53aa9a
Autor:
Takashi Murakami, Yukihiko Hiroshima, Kentaro Miyake, Tasuku Kiyuna, Itaru Endo, Ming Zhao, Robert M. Hoffman
Publikováno v:
Cells, Vol 8, Iss 6, p 599 (2019)
We developed tumor-targeting Salmonella typhimurium (S. typhimurium) A1-R, a facultative anaerobe that is an auxotroph of leucine and arginine. The tumor-targeting efficacy of S. typhimurium A1-R was demonstrated in vivo and vitro using several malig
Externí odkaz:
https://doaj.org/article/9445e999fa8248eab4c15b3e9a0ea42f