Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Yukie Mitsuda"'
Autor:
Yasuhiro Nishiyama, Brian O'Nuallain, Eric L. Brown, Sari Sonoda, Kenji Watanabe, Sudhir Paul, Sarah K. Murphy, Stanley R. Primmer, Stephanie Planque, Mariko Hara, Richard Massey, Yukie Mitsuda
Publikováno v:
Journal of Biological Chemistry. 289:13243-13258
Peptide bond-hydrolyzing catalytic antibodies (catabodies) could degrade toxic proteins, but acquired immunity principles have not provided evidence for beneficial catabodies. Transthyretin (TTR) forms misfolded β-sheet aggregates responsible for ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c88c167d9e9ca4173044fb117362644f
https://doi.org/10.1074/jbc.m114.557231
https://doi.org/10.1074/jbc.m114.557231
Autor:
Yasuhiro Nishiyama, Stephanie Planque, Yukie Mitsuda, Marcin Sieńczyk, Carl V. Hanson, Mary Kate Morris, Amit Kumar, Feng Gao, Jason P. Mooney, Miguel A. Escobar, Dipanjan Ghosh, Sudhir Paul, Maria Salas
Publikováno v:
AIDS. 24:875-884
To identify an HIV epitope suitable for vaccine development.Diverse HIV-1 strains express few structurally constant regions on their surface vulnerable to neutralizing antibodies. The mostly conserved CD4-binding site (CD4BS) of gp120 is essential fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::601c8c66ed3caa60c1c895ce80d4df02
https://doi.org/10.1097/qad.0b013e3283376e88
https://doi.org/10.1097/qad.0b013e3283376e88
Autor:
Maria Salas, Giovanni Nitti, Lei Jin, Hiroaki Taguchi, Stephane Boivin, Jindrich Symersky, Carl V. Hanson, Yukie Mitsuda, Stephanie Planque, Yasuhiro Nishiyama, Sudhir Paul, Marcin Sieńczyk
Publikováno v:
Journal of Biological Chemistry. 284:30627-30642
We describe murine monoclonal antibodies (mAbs) raised by immunization with an electrophilic gp120 analog (E-gp120) expressing the rare ability to neutralize genetically heterologous human immunodeficiency virus (HIV) strains. Unlike gp120, E-gp120 f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ba51de8b2fba1ff6df16957dfb92501
https://doi.org/10.1074/jbc.m109.032185
https://doi.org/10.1074/jbc.m109.032185
Autor:
Yasuhiro Nishiyama, Hiroaki Taguchi, Yukie Mitsuda, Haynes W. Sheppard, Sudhir Paul, Miguel A. Escobar, Robert A. Kyle, Carl V. Hanson, Mary Kate Morris, Maria Salas, Robert L. Hunter, Stephanie Planque, Pablo C. Okhuysen
Publikováno v:
AIDS Research and Human Retroviruses. 23:1541-1554
Antibody hydrolysis of the superantigenic gp120 site and HIV-1 neutralization was studied as a potential anti-HIV mechanism in uninfected humans. gp120 hydrolysis by purified serum and salivary antibodies was determined by electrophoresis and peptide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::607be025e8dee57529f2a9c8ec27191d
https://doi.org/10.1089/aid.2007.0081
https://doi.org/10.1089/aid.2007.0081
Autor:
Yasuhiro Nishiyama, Stephanie Planque, Sudhir Paul, Hiroaki Taguchi, Yukie Mitsuda, Maria Salas, Carl V. Hanson
Publikováno v:
Journal of Biological Chemistry. 282:31250-31256
Rare monoclonal antibodies (Abs) can form irreversible complexes with antigens by enzyme-like covalent nucleophile-electrophile pairing. To determine the feasibility of applying irreversible antigen inactivation by Abs as the basis of vaccination aga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73c33fb17a2cfad2a602506b2e344b48
https://doi.org/10.1074/jbc.m706471200
https://doi.org/10.1074/jbc.m706471200
Autor:
Mariko Hara, Sudhir Paul, Yasuhiro Nishiyama, Yukie Mitsuda, Hiroaki Taguchi, Stephanie Planque, Robert A. Kyle
Publikováno v:
Molecular Biotechnology. 36:113-122
IgG class antibodies express catalytic activities rarely and at very low levels. Here, we studied polyclonal IgA and IgG preparations from healthy human sera and saliva for the ability to hydrolyze model peptidyl-aminomethylcoumarin (peptide-AMC) sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f30474b13f181aa746693f7dc4a02045
https://doi.org/10.1007/s12033-007-0003-7
https://doi.org/10.1007/s12033-007-0003-7
Autor:
Yasuhiro Nishiyama, Einar M. Sigurdsson, Robert P. Friedland, Sari Sonoda, Yan Lin, Sudhir Paul, Brian O'Nuallain, Hiroaki Taguchi, Steven J. Kolodziej, Stephanie Planque, Mariko Hara, Hameetha B.R. Sait, Richard Massey, Veronica Gonzalez, Yukie Mitsuda, Ken Ichiro Fukuchi
Publikováno v:
The Journal of biological chemistry. 290(16)
Classical immunization methods do not generate catalytic antibodies (catabodies), but recent findings suggest that the innate antibody repertoire is a rich catabody source. We describe the specificity and amyloid β (Aβ)-clearing effect of a catabod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a4d32976523dd41668c79328c064dcf
https://pubmed.ncbi.nlm.nih.gov/25724648
https://pubmed.ncbi.nlm.nih.gov/25724648
Autor:
Yukie Mitsuda, Hiroaki Taguchi, Sudhir Paul, Yasuhiro Nishiyama, Stephanie Planque, Yogesh Bangale, Sangeeta Karle, Gita Bhatia
Publikováno v:
Journal of Biological Chemistry. 279:7877-7883
We report the selective inactivation of proteolytic antibodies (Abs) to an autoantigen, the neuropeptide vasoactive intestinal peptide (VIP), by a covalently reactive analog (CRA) of VIP containing an electrophilic phosphonate diester at the Lys20 re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5205e04e019a7e42e98e50f2886f713
https://doi.org/10.1074/jbc.m310950200
https://doi.org/10.1074/jbc.m310950200
Publikováno v:
Biotechnology and Bioengineering. 86:217-225
A monoclonal antibody (MAb), ECL2B-2, was obtained by immunizing a peptide possessing a part of a sequence of a chemokine receptor, CCR-5, which is present as a membrane protein on the macrophage surface, and which plays an important role in human im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::114b6585d177c326f40de1c117f1a512
https://doi.org/10.1002/bit.20031
https://doi.org/10.1002/bit.20031
Publikováno v:
Journal of Immunological Methods. 269:283-298
Generation of antibodies with the ability to destroy targeted viral coat proteins or tumor antigens is an important aim in current research aimed at developing superior catalytic antibodies. To this end, we raised a monoclonal antibody against a disc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aa1f8b7e0b3e7b43002b40b9b930d39
https://doi.org/10.1016/s0022-1759(02)00242-9
https://doi.org/10.1016/s0022-1759(02)00242-9