Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Yukie Takano"'
Autor:
Kyoko Adachi, Koichi Tanabe, Yukie Takano, Kazutaka Kawabata, Yoshikazu Shizuri, Yoshimasa Uehara, Erwin Lamping, Masakazu Niimi
Publikováno v:
Biochemical and Biophysical Research Communications. 364:990-995
Novel inhibitors of fungal ATP-binding cassette transporters were obtained by screening compounds and crude extracts from marine-derived fungi and bacteria using disk diffusion assays of Saccharomyces cerevisiae strains overexpressing a variety of fu
Autor:
Toshihiro Aoyama, N Selvamuthu Kumaraswami, Masakazu Niimi, Hironobu Nakayama, Martin Bard, Koichi Tanabe, Yukie Takano, Hiroji Chibana, Laurel J. Metzler, Daiki Takemori, Sung Wu, Wesley Hodgson
Publikováno v:
Journal of Antimicrobial Chemotherapy. 60:1264-1272
Objectives The uptake of endogenous sterol from serum may allow Candida glabrata to survive azole treatment. This study aims to determine the contribution of a sterol transporter that alters fluconazole sensitivity in the presence of serum. Methods B
Autor:
Haruo Watanabe, Kazuo Suzuki, Akiko Ishida-Okawara, Nobuyo Maeda, Yukie Takano, Yasuaki Aratani, Hisayoshi Akagawa, Hideki Koyama, Fumiaki Kura
Publikováno v:
Journal of Medical Microbiology. 55:1291-1299
Thein vivocontribution of reactive oxygen species produced by neutrophils againstCryptococcusinfection is not widely recognized. Myeloperoxidase (MPO) is a neutrophil-specific enzyme that catalyses the production of hypohalous acids such as HOCl from
Autor:
Koichi Tanabe, Yuki Nagai, Takashi Umeyama, Masakazu Niimi, Yukie Takano, Nozomu Hanaoka, Yoshimasa Uehara, Aki Kaneko
Publikováno v:
Molecular Microbiology. 55:381-395
Saccharomyces cerevisiae Hsl1p is a Ser/Thr protein kinase that regulates cell morphology. We identified Candida albicans CaHSL1 and analysed its function in C. albicans. Cells lacking CaHsl1p exhibited filamentous growth under yeast growth condition
Autor:
Fumiaki Kura, Haruo Watanabe, Kazuo Suzuki, Yukie Takano, Nobuyo Maeda, Hideki Koyama, Yasuaki Aratani, Hisayoshi Akagawa
Publikováno v:
The Journal of Infectious Diseases. 182:1276-1279
Myeloperoxidase (MPO), which is located within neutrophils capable of producing hypochlorous acid, is active in vitro against bacteria and fungi. However, MPO-deficient persons are usually healthy. To define the in vivo contribution of MPO to early h
Publikováno v:
Japanese Journal of Infectious Diseases. 62:306-308
Autor:
Hisayoshi Akagawa, Kazuyuki Dobashi, Reiko Izui, Yukie Takano, Tomohiro Sameshima, Satoshi Mizuno, Ayako Ishii, Naoto Kawamura, Takeo Yoshioka
Publikováno v:
ChemInform. 31
Stresgenin B was isolated as an inhibitor of heat-induced heat shock protein (HSP) gene expression from a culture broth of Streptomyces sp. AS-9 by silica gel chromatography and HPLC. The molecular formula of the novel compound was determined as C11H
Autor:
Satoshi Mizuno, Kaori Masuda, Kazue Kawaguchi, Yukie Takano, Kunimoto Hotta, Kazuo Watanabe, Naline Nilubol, Akiko Ishida-Okawara, Hisayoshi Akagawa, Koichi Tokuda, Kazunaga Yazawa, Michio Shibata, Kazuo Suzuki, Yukio Kimoto
Publikováno v:
The Journal of Antibiotics. 44:524-532
We found inhibitors, designated aseanostatins P1 and P5, against myeloperoxidase (MPO) release from human polymorphonuclear leukocytes (PMN). Aseanostatins were extracted from an actinomycete isolated in Thailand and purified by a series of column ch
Autor:
Nozomu Hanaoka, Hajime Fugo, Yoshimasa Uehara, Yukie Takano, Kazutoshi Shibuya, Masakazu Niimi
Publikováno v:
Eukaryotic cell. 7(10)
Protein phosphatases are critical for the regulation of many cellular processes. Null mutants of 21 putative protein phosphatases of Candida albicans were constructed by consecutive allele replacement using the URA3 and ARG4 marker genes. A simple si
Autor:
Masakazu, Niimi, Shun-ichi, Wada, Koichi, Tanabe, Aki, Kaneko, Yukie, Takano, Takashi, Umeyama, Nozomu, Hanaoka, Yoshimasa, Uehara, Erwin, Lamping, Kyoko, Niimi, Sarah, Tsao, Ann R, Holmes, Brian C, Monk, Richard D, Cannon
Publikováno v:
Japanese journal of infectious diseases. 58(1)
Clinically important resistance of fungal pathogens to azole antifungal drugs is most frequently caused by the over-expression of energy-dependent drug efflux pumps. These pumps usually belong to either the ATP-binding cassette (ABC) family or the Ma