Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Yuki Toyama"'
Autor:
Yuki Toyama, Ichio Shimada
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The DEAD-box RNA helicase (DDX) plays a central role in many aspects of RNA metabolism by remodeling the defined structure of RNA molecules. While a number of structural studies have revealed the atomistic details of the interaction between
Externí odkaz:
https://doaj.org/article/ab98ab336db7417f9a8c469bc0024ff2
Autor:
Yuki Toyama, Lewis E. Kay
Publikováno v:
Journal of Magnetic Resonance Open, Vol 12, Iss , Pp 100065- (2022)
NMR studies exploit spin relaxation in a multitude of different ways, providing information on molecular structure and dynamics. Calculating the relaxation rates of NMR active nuclei in multi-spin systems is often a prerequisite for the proper analys
Externí odkaz:
https://doaj.org/article/92770d57c4714877a7be5f77ec60d3c6
Publikováno v:
Plants, Vol 12, Iss 4, p 948 (2023)
Polyphenol-rich rabbiteye blueberry (Vaccinium virgatum Aiton) leaves have attracted attention as a food material. In this study, we compared the total polyphenols, total proanthocyanidin content, and antioxidant activity of the leaves of 18 blueberr
Externí odkaz:
https://doaj.org/article/a1ed1f26ba284417aa42194c86913c4e
Autor:
Yuta Iwahashi, Yuki Toyama, Shunsuke Imai, Hiroaki Itoh, Masanori Osawa, Masayuki Inoue, Ichio Shimada
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Potassium ion channels control K+ permeation across cell membranes and mutations that cause cardiovascular and neural diseases are known. Here, the authors perform NMR measurements with the prototypical K+ channel from Streptomyces lividans, KcsA and
Externí odkaz:
https://doaj.org/article/1e91ff52d72149278985a050c03132cb
Autor:
Hanaho Kano, Yuki Toyama, Shunsuke Imai, Yuta Iwahashi, Yoko Mase, Mariko Yokogawa, Masanori Osawa, Ichio Shimada
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Opening of G protein-gated inwardly rectifying potassium channels (GIRK) is coupled to the activation of a GPCR. Here the authors use NMR and cell-based BRET assays to gain insights into the mechanisms underlying family-specific activation and find t
Externí odkaz:
https://doaj.org/article/1d3c5f17ee3f414881ec083bebb5692c
Autor:
Koh Takeuchi, Yutaka Kofuku, Shunsuke Imai, Takumi Ueda, Yuji Tokunaga, Yuki Toyama, Yutaro Shiraishi, Ichio Shimada
Publikováno v:
Membranes, Vol 11, Iss 8, p 604 (2021)
A primary biological function of multi-spanning membrane proteins is to transfer information and/or materials through a membrane by changing their conformations. Therefore, particular dynamics of the membrane proteins are tightly associated with thei
Externí odkaz:
https://doaj.org/article/399a52ea34974dbb844af3cc8f0e5f6e
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Heterotrimeric guanine-nucleotide-binding proteins (G proteins) act as molecular switches. Here the authors use NMR relaxation analyses, which reveal the dynamics of G protein alpha subunit binding to GDP on a microsecond timescale.
Externí odkaz:
https://doaj.org/article/985f87fc49594e81ade0f518bf2a63de
Publikováno v:
Journal of Biomolecular NMR. 76:137-152
Autor:
ELIAS, ASRES, LAUNIO, CHERYLL CASIWAN, KUMI YASUNOBU, YUKI TOYAMA, ENDALEW, BIRARA, ALTAKI, MARYAN J.
Publikováno v:
International Journal of Environmental & Rural Development; Dec2023, Vol. 14 Issue 2, p80-86, 7p
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(36)
Electrostatic interactions and charge balance are important for the formation of biomolecular condensates involving proteins and nucleic acids. However, a detailed, atomistic picture of the charge distribution around proteins during the phase-separat