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pro vyhledávání: '"Yuki Toi"'
Autor:
Motokazu Ito, Masasuke Ohno, Ken Ichiro Iwami, Daiki Ito, Kazuya Motomura, Jun Yoshida, Yuki Toi, Kazuhiro Yoshikawa, Atsushi Natsume, Hidetaka Iwamizu, Toshihiko Wakabayashi, Kana Noritake
Publikováno v:
Cancer Science. 101:2518-2524
The isotype of epidermal growth factor receptor variant III (EGFRvIII) is often identified in glioblastomas. Previously, we created a mouse monoclonal antibody, 3C10 (IgG2b), that specifically recognized EGFRvIII, and a recombinant single-chain varia
Autor:
Toshihiko Wakabayashi, Yutaka Kondo, Hiroshi Toda, Osamu Nakayama, Makoto Sato, Yugo Kishida, Kazuya Motomura, Yuki Toi, Atsushi Natsume, Hiroko Koyama, Masaaki Suzuki, Keiji Matsuda
Publikováno v:
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 33(2)
The DNA repair protein O (6)-methylguanine-DNA methyltransferase (MGMT, AGT) is a determinant of the resistance of tumor cells to alkylating anticancer agents that target the O(6) position of guanine. MGMT promoter methylation in tumors is regarded a