Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Yuki Sugihara"'
Autor:
Junichi Takahashi, Hady Yuki Sugihara, Shu Kato, Sayaka Nagata, Ryuichi Okamoto, Tomohiro Mizutani
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102374- (2023)
Summary: Current techniques for producing induced-pluripotent-stem-cell-derived mid/hindgut spheroids have faced major hurdles in consistency and reproducibility. Here, we present a protocol that uses mid/hindgut cells to generate homogeneous spheroi
Externí odkaz:
https://doaj.org/article/8fbfcef431e44a2e99a841fee9adb792
Autor:
Hideki Minematsu, Said M. Afify, Yuki Sugihara, Ghmkin Hassan, Maram H. Zahra, Akimasa Seno, Masaki Adachi, Masaharu Seno
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Previously, our group has demonstrated establishment of Cancer Stem Cell (CSC) models from stem cells in the presence of conditioned medium of cancer cell lines. In this study, we tried to identify the factors responsible for the induction o
Externí odkaz:
https://doaj.org/article/2dd3be2d767c48678d0e4eb56aa14b91
Autor:
Ryuichi Okamoto, Hiromichi Shimizu, Kohei Suzuki, Ami Kawamoto, Junichi Takahashi, Mao Kawai, Sayaka Nagata, Yui Hiraguri, Sayaka Takeoka, Hady Yuki Sugihara, Shiro Yui, Mamoru Watanabe
Publikováno v:
Regenerative Therapy, Vol 13, Iss , Pp 1-6 (2020)
Inflammatory bowel disease (IBD) consists of two major idiopathic gastrointestinal diseases: ulcerative colitis and Crohn's disease. Although a significant advance has been achieved in the treatment of IBD, there remains a particular population of pa
Externí odkaz:
https://doaj.org/article/a19ae1be37fd4ce58f4407ae8f6b0bd4
Autor:
Reiko Kuno, Go Ito, Ami Kawamoto, Yui Hiraguri, Hady Yuki Sugihara, Sayaka Takeoka, Sayaka Nagata, Junichi Takahashi, Mao Tsuchiya, Sho Anzai, Tomohiro Mizutani, Hiromichi Shimizu, Shiro Yui, Shigeru Oshima, Kiichiro Tsuchiya, Mamoru Watanabe, Ryuichi Okamoto
Publikováno v:
Biochemistry and Biophysics Reports, Vol 25, Iss , Pp 100906- (2021)
Notch signaling is activated in the intestinal epithelial cells (IECs) of patients with inflammatory bowel disease (IBD), and contributes to mucosal regeneration. Our previous study indicated that TNF-α and Notch signaling may synergistically promot
Externí odkaz:
https://doaj.org/article/0a375b89ba1e4c71a4f4c238859107d9
Publikováno v:
AIJ Journal of Technology and Design. 29:492-497
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::619856b3854f98662ad575e96a791dd1
https://doi.org/10.3130/aijt.29.492
https://doi.org/10.3130/aijt.29.492
Publikováno v:
AIJ Journal of Technology and Design. 28:471-475
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::936ac4affe9c3333eda553e94bff99b0
https://doi.org/10.3130/aijt.28.471
https://doi.org/10.3130/aijt.28.471
Autor:
Minami Hama, Sho Anzai, Junichi Takahashi, Hady Yuki Sugihara, Shigeru Oshima, Tomohiro Mizutani, M. Tsuchiya, Hiromichi Shimizu, Sayaka Nagata, Go Ito, Mamoru Watanabe, Yui Hiraguri, Kiichiro Tsuchiya, Sayaka Takeoka, Ryuichi Okamoto, Shiro Yui, Reiko Kuno, Ami Kawamoto, Kohei Suzuki
Publikováno v:
Biochemical and Biophysical Research Communications. 542:40-47
Inflammatory bowel disease (IBD) comprises two major subtypes, ulcerative colitis (UC) and Crohn's disease, which are multifactorial diseases that may develop due to genetic susceptibility, dysbiosis, or environmental factors. Environmental triggers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a4a1988443cedb70cc0c9c58c3ddc38
https://doi.org/10.1016/j.bbrc.2021.01.021
https://doi.org/10.1016/j.bbrc.2021.01.021
Autor:
Junichi Takahashi, Tomohiro Mizutani, Hady Yuki Sugihara, Sayaka Nagata, Shu Kato, Yui Hiraguri, Sayaka Takeoka, Mao Tsuchiya, Reiko Kuno, Sei Kakinuma, Mamoru Watanabe, Ryuichi Okamoto
Publikováno v:
Cell reports methods. 2(11)
Human intestinal organoids (HIOs) derived from human pluripotent stem cells (hPSCs) hold great promise for translational medical applications. A common method to obtain HIOs has been to harvest floating hindgut spheroids arising from hPSCs. As this t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2d21ff4f416987021cc1b8d56bb1253
https://pubmed.ncbi.nlm.nih.gov/36452871
https://pubmed.ncbi.nlm.nih.gov/36452871
Autor:
Shiro Yui, Hiromichi Shimizu, Ami Kawamoto, Satoshi Watanabe, Mamoru Watanabe, Sayaka Nagata, Hady Yuki Sugihara, Junichi Takahashi, Shigeru Oshima, Sakurako Kobayashi, Yui Hiraguri, Sayaka Takeoka, Sho Anzai, Ryuichi Okamoto, Reiko Kuno, Kohei Suzuki, Mao Kawai
Publikováno v:
Biochemical and Biophysical Research Communications. 524:533-541
The early-phase wound repair response of the intestinal epithelium is characterized by rapid and organized cell migration. This response is regulated by several humoral factors, including TGF-β. However, due to a lack of appropriate models, the prec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61214cae36e59a237be32c5c1daf344a
https://doi.org/10.1016/j.bbrc.2020.01.108
https://doi.org/10.1016/j.bbrc.2020.01.108
Autor:
Hady Yuki Sugihara, Sayaka Nagata, Junichi Takahashi, Yui Hiraguri, Hiromichi Shimizu, Ryuichi Okamoto, Mamoru Watanabe, Sayaka Takeoka, Shiro Yui, Mao Kawai, Kohei Suzuki, Ami Kawamoto
Publikováno v:
Regenerative Therapy
Regenerative Therapy, Vol 13, Iss, Pp 1-6 (2020)
Regenerative Therapy, Vol 13, Iss, Pp 1-6 (2020)
Inflammatory bowel disease (IBD) consists of two major idiopathic gastrointestinal diseases: ulcerative colitis and Crohn's disease. Although a significant advance has been achieved in the treatment of IBD, there remains a particular population of pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::978eb52d518264a3fa6de49b7a1bfdd6
http://europepmc.org/articles/PMC6961757
http://europepmc.org/articles/PMC6961757