Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Yuki Sugaya"'
Autor:
Toshimitsu Suzuki, Toshifumi Suzuki, Matthieu Raveau, Noriko Miyake, Genki Sudo, Yoshinori Tsurusaki, Takaki Watanabe, Yuki Sugaya, Tetsuya Tatsukawa, Emi Mazaki, Atsushi Shimohata, Itaru Kushima, Branko Aleksic, Tomoko Shiino, Tomoko Toyota, Yoshimi Iwayama, Kentaro Nakaoka, Iori Ohmori, Aya Sasaki, Ken Watanabe, Shinichi Hirose, Sunao Kaneko, Yushi Inoue, Takeo Yoshikawa, Norio Ozaki, Masanobu Kano, Takeyoshi Shimoji, Naomichi Matsumoto, Kazuhiro Yamakawa
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 7, Pp 1117-1131 (2020)
Abstract Objective Neurodevelopmental disorders (NDDs) often associate with epilepsy or craniofacial malformations. Recent large‐scale DNA analyses identified hundreds of candidate genes for NDDs, but a large portion of the cases still remain unexp
Externí odkaz:
https://doaj.org/article/67ede20262d942a7af3cbb0166cf35a4
Autor:
Yuki Sugaya, Masanobu Kano
Publikováno v:
Frontiers in Neural Circuits, Vol 15 (2022)
Research on endocannabinoid signaling has greatly advanced our understanding of how the excitability of neural circuits is controlled in health and disease. In general, endocannabinoid signaling at excitatory synapses suppresses excitability by inhib
Externí odkaz:
https://doaj.org/article/84f94e98eb364140992f63b6c9d3e21b
Autor:
Kazuya Toriumi, Stefano Berto, Shin Koike, Noriyoshi Usui, Takashi Dan, Kazuhiro Suzuki, Mitsuhiro Miyashita, Yasue Horiuchi, Akane Yoshikawa, Mai Asakura, Kenichiro Nagahama, Hsiao-Chun Lin, Yuki Sugaya, Takaki Watanabe, Masanobu Kano, Yuki Ogasawara, Toshio Miyata, Masanari Itokawa, Genevieve Konopka, Makoto Arai
Publikováno v:
Redox Biology, Vol 45, Iss , Pp 102057- (2021)
Methylglyoxal (MG) is a reactive and cytotoxic α-dicarbonyl byproduct of glycolysis. Our bodies have several bio-defense systems to detoxify MG, including an enzymatic system by glyoxalase (GLO) 1 and GLO2. We identified a subtype of schizophrenia p
Externí odkaz:
https://doaj.org/article/2b8b52bc95e345e29e2d14d00d5416bb
Autor:
Alvaro Carrier-Ruiz, Yuki Sugaya, Deependra Kumar, Pablo Vergara, Iyo Koyanagi, Sakthivel Srinivasan, Toshie Naoi, Masanobu Kano, Masanori Sakaguchi
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100238- (2021)
Summary: Adult-born neurons (ABNs) in the dentate gyrus bestow unique cellular plasticity to the mammalian brain. We recently found that the activity of ABNs during sleep is necessary for memory consolidation. Here, we describe our method for Ca2+ im
Externí odkaz:
https://doaj.org/article/dfbb9671ba0b4bb0bbadaaac38163366
Crucial Roles of the Endocannabinoid 2-Arachidonoylglycerol in the Suppression of Epileptic Seizures
Autor:
Yuki Sugaya, Maya Yamazaki, Motokazu Uchigashima, Kenta Kobayashi, Masahiko Watanabe, Kenji Sakimura, Masanobu Kano
Publikováno v:
Cell Reports, Vol 16, Iss 5, Pp 1405-1415 (2016)
Endocannabinoid signaling is considered to suppress excessive excitability of neural circuits and to protect the brain from seizures. However, the precise mechanisms of this effect are poorly understood. Here, we report that 2-arachidonoylglycerol (2
Externí odkaz:
https://doaj.org/article/fc3bde25d3d34398b710e6b4ca93d760
Autor:
Takanobu Nakazawa, Ryota Hashimoto, Kazuto Sakoori, Yuki Sugaya, Asami Tanimura, Yuki Hashimotodani, Kazutaka Ohi, Hidenaga Yamamori, Yuka Yasuda, Satomi Umeda-Yano, Yuji Kiyama, Kohtarou Konno, Takeshi Inoue, Kazumasa Yokoyama, Takafumi Inoue, Shusuke Numata, Tohru Ohnuma, Nakao Iwata, Norio Ozaki, Hitoshi Hashimoto, Masahiko Watanabe, Toshiya Manabe, Tadashi Yamamoto, Masatoshi Takeda, Masanobu Kano
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-17 (2016)
The molecular mechanisms of neurotrophin receptor trafficking are only partially understood. Here the authors show that ARHGAP33 interacts with SORT1 to regulate TrkB trafficking, the dysfunction of which impairs synapse development and leads to schi
Externí odkaz:
https://doaj.org/article/76c7f59a209646a0ada889e8e6621f22
Autor:
Hidetoshi Kassai, Yuki Sugaya, Shoko Noda, Kazuki Nakao, Tatsuya Maeda, Masanobu Kano, Atsu Aiba
Publikováno v:
Cell Reports, Vol 7, Iss 5, Pp 1626-1639 (2014)
Mammalian target of rapamycin (mTOR) has been implicated in human neurological diseases such as tuberous sclerosis complex (TSC), neurodegeneration, and autism. However, little is known about when and how mTOR is involved in the pathogenesis of these
Externí odkaz:
https://doaj.org/article/01f1f167120d40ecbfe708250b8f5c1d
Autor:
Takanobu Nakazawa, Ryota Hashimoto, Kazuto Sakoori, Yuki Sugaya, Asami Tanimura, Yuki Hashimotodani, Kazutaka Ohi, Hidenaga Yamamori, Yuka Yasuda, Satomi Umeda-Yano, Yuji Kiyama, Kohtarou Konno, Takeshi Inoue, Kazumasa Yokoyama, Takafumi Inoue, Shusuke Numata, Tohru Ohnuma, Nakao Iwata, Norio Ozaki, Hitoshi Hashimoto, Masahiko Watanabe, Toshiya Manabe, Tadashi Yamamoto, Masatoshi Takeda, Masanobu Kano
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-1 (2016)
Nature Communications 7: Article number:10594 (2016); Published: 03 February 2016; Updated: 20 April 2016 Previous work by Rosário et al. 2007 and Schuster et al. 2015 describing the role of ARHGAP33 in regulating dendrite and dendritic spine develo
Externí odkaz:
https://doaj.org/article/b90caf57ff39460bacbf43e98e3dd195
Autor:
Pablo Vergara, Yuteng Wang, Sakthivel Srinivasan, Yoan Cherasse, Toshie Naoi, Yuki Sugaya, Takeshi Sakurai, Masanobu Kano, Masanori Sakaguchi
Neuron-tracking algorithms exhibit suboptimal performance in calcium imaging when the same neurons are not consistently detected, as unmatched features hinder intersession alignment. CaliAli addresses this issue by employing an alignment-before-extra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77d73a8e4904bc625861c18130ef7cf9
https://doi.org/10.1101/2023.05.19.540935
https://doi.org/10.1101/2023.05.19.540935
Autor:
Yu Shinjyo, Naoya Midorikawa, Takashi Matsumoto, Yuki Sugaya, Yoshiki Ozawa, Ayumi Oana, Chiaki Horie, Hirofumi Yoshikawa, Yasuhiro Takahashi, Toshio Hasegawa, Kei Asai
Publikováno v:
The Journal of General and Applied Microbiology. 68:62-70
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b71e1f0a44f6b70198c3c6a8dbd9a942
https://doi.org/10.2323/jgam.2021.09.005
https://doi.org/10.2323/jgam.2021.09.005