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Clinical utility of a liquid biopsy diagnostic approach in lung cancer using amplicon-based next-generation sequencing in parallel with allele-specific PCR

Autor: Seng Weng Wong, Wei Shuen Ng, Carina Tay, Chaitanya Gupta, Yukti Choudhury, Jing Shan Lim, Tai-Chung Lam, Michelle Pek, Siu Kei Au, Yuki Sim, Wing Kin Sze, Min-Han Tan, Yew-Oo Tan, Wai Min Phyo, William Foo, Victor Hsue, Tan Min Chin, Yiliang Ho

Publikováno v: Journal of Clinical Oncology. 38:e21516-e21516

e21516 Background: The utility of a liquid biopsy test for diagnosis and treatment is determined by its accuracy, molecular target coverage and timeliness to a clinically informative result. We describe our clinical experience of providing comprehens

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e228a6a0a1f8251526be6e37ea502b57
https://doi.org/10.1200/jco.2020.38.15_suppl.e21516

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Detection of actionable gene mutations in breast cancer by amplicon-based next-generation sequencing liquid biopsy

Autor: Wei Shuen Ng, Yiliang Ho, Wai Min Phyo, Yuki Sim, Yukti Choudhury, Hui Ti See, Janice Tsang, Carina Tay, Min-Han Tan, Chaitanya Gupta, Jing Shan Lim

Publikováno v: Journal of Clinical Oncology. 38:1035-1035

1035 Background: The PI3K-inhibitor, alpelisib, was approved for the treatment of hormone receptor (HR)-positive, HER2-negative breast cancers with PIK3CA mutations based on findings from the SOLAR-1 trial. PIK3CA-positivity in tumor tissue was 29% (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2af36c243099568a4d58770a4b49d0ce
https://doi.org/10.1200/jco.2020.38.15_suppl.1035

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