Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Yuki Nishimura-Sakurai"'
Autor:
Yasuhiro Itsui, Yuki Nishimura-Sakurai, Seishin Azuma, Yasuhiro Asahina, Yujiro Tanaka, Atsuko Imada, Etsuko Hashimoto, Takashi Itoh, Miyako Murakawa, Makiko Taniai, Fukiko Kawai-Kitahata, Satoshi Otani, Sei Kakinuma, Mina Nakagawa, Shun Kaneko, Hiroko Nagata, Sayuri Nitta, Mamoru Watanabe
Publikováno v:
Kanzo. 57:382-390
Autor:
Mina Nakagawa, Satoshi Otani, Yasuhiro Asahina, Yasuhiro Itsui, Eiko Takeichi, Fukiko Kawai-Kitahata, Miyako Murakawa, Mamoru Watanabe, Seishin Azuma, Sei Kakinuma, Sayuri Nitta, Kenichiro Kobashi, Yuki Nishimura-Sakurai
Publikováno v:
Kanzo. 57:405-411
Autor:
Megumi Tasaka-Fujita, Yasuhiro Itsui, Yasuhiro Asahina, Takako Watanabe, Miyako Murakawa, Sei Kakinuma, Mina Nakagawa, Fumio Goto, Fukiko Kawai-Kitahata, Shun Kaneko, Mamoru Watanabe, Miki Taniguchi, Hiroko Nagata, Satoshi Ootani, Yuki Nishimura-Sakurai, Seishin Azuma
Publikováno v:
Hepatology Research. 46:312-319
Aim For intermediate hepatocellular carcinoma (HCC), transcatheter arterial chemoembolization (TACE) therapy is recommended in the guidelines as a monotherapy, although TACE is a non-curative therapy. The aims of the present study were to evaluate th
Autor:
Takako Watanabe, Mina Nakagawa, Satoshi Otani, Mamoru Watanabe, Fumio Goto, Miki Taniguchi, Fukiko Kawai-Kitahata, Sayuri Nitta, Naoya Sakamoto, Yuki Nishimura-Sakurai, Sei Kakinuma, Yasuhiro Asahina, Akiko Kusano-Kitazume, Miyako Murakawa, Yasuhiro Itsui, Seishin Azuma
Publikováno v:
Journal of Gastroenterology and Hepatology. 30:1075-1084
Background and Aim Interferon (IFN) λ plays an important role in innate immunity to protect against hepatitis C viral (HCV) infection. Single nucleotide polymorphisms (SNPs) near IL28B (IFNλ3) are strongly associated with treatment response to IFN
Autor:
Mamoru Watanabe, Megumi Tasaka-Fujita, Kako Mishima, Naoya Sakamoto, Miyako Murakawa, Yasuhiro Asahina, Mina Nakagawa, Takashi Fujita, Sayuri Nitta, Sei Kakinuma, Mitsutoshi Yoneyama, Yuki Nishimura-Sakurai, Seishin Azuma, Kei Kiyohashi, Akiko Kusano-Kitazume
Publikováno v:
Hepatology. 57:46-58
Hepatitis C virus (HCV) infection blocks cellular interferon (IFN)-mediated antiviral signaling through cleavage of Cardif by HCV-NS3/4A serine protease. Like NS3/4A, NS4B protein strongly blocks IFN-β production signaling mediated by retinoic acid
Autor:
Seishin Azuma, Tomoyuki Tsunoda, Masato Miyoshi, Shuji Tohda, Sei Kakinuma, Yasuhiro Itsui, Yasuhiro Asahina, Miyako Murakawa, Mina Nakagawa, Mamoru Watanabe, Satoshi Otani, Fukiko Kawai-Kitahata, Yuki Nishimura-Sakurai, Fumio Goto, Yu Asano, Shun Kaneko, Hiroko Nagata, Sayuri Nitta, Naoko Tojo
Publikováno v:
Hepatology international. 10(6)
Wisteria floribunda agglutinin positive (WFA+) Mac-2-binding protein (M2BPGi) is a noninvasive glyco-marker for liver fibrosis. This study evaluated the utility of serial measurement of serum M2BPGi and total M2BP as a predictor of fibrosis and the d
Autor:
Izumi Onozuka, Mamoru Watanabe, Seishin Azuma, Takako Watanabe, Yuki Nishimura-Sakurai, Miyako Murakawa, Sei Kakinuma, Kei Kiyohashi, Masashi Mizokami, Sayuri Nitta, Yasuhito Tanaka, Akiko Kusano-Kitazume, Kohei Yoshino, Naoya Sakamoto, Yasuhiro Itsui, Mina Nakagawa
Publikováno v:
Hepatology International. 7:153-161
Genetic variation leading to inosine triphosphatase (ITPA) deficiency protects chronic hepatitis C patients receiving ribavirin against hemolytic anemia. The relationship between ITPA gene variation and serum ribavirin concentration was analyzed in a
Autor:
Takako Watanabe, Sei Kakinuma, Mina Nakagawa, Kei Kiyohashi, Mamoru Watanabe, Mayumi Ueyama, Miyako Murakawa, Seishin Azuma, Naoya Sakamoto, Yuki Nishimura-Sakurai, Sayuri Nitta, Kiichiro Tsuchiya, Yasuhiro Itsui, Yusuke Funaoka, Shinya Oooka, Akiko Kitazume
Publikováno v:
Antimicrobial Agents and Chemotherapy. 55:2537-2545
A lack of patient response to alpha interferon (α-IFN) plus ribavirin (RBV) treatment is a major problem in eliminating hepatitis C virus (HCV). We screened chemical libraries for compounds that enhanced cellular responses to α-IFN and identified a
Autor:
Takanobu Kato, Yasuhiro Itsui, Sei Kakinuma, Mamoru Watanabe, Yuki Nishimura-Sakurai, Mina Nakagawa, Seishin Azuma, Tetsuya Nakamura, Takaji Wakita, Naoya Sakamoto, Machi Yamamoto, Kiichiro Tsuchiya
Publikováno v:
Hepatology Research. 41:258-269
Aim: Studies of the complete hepatitis C virus (HCV) life cycle have become possible with the development of a HCV-JFH1 cell culture system. Methods: In this study, we constructed two fluorescence protein-tagged recombinant JFH1 virus clones, JFH1-EY
Autor:
Yuki Nishimura-Sakurai, Katsushi Tokunaga, Seishin Azuma, Shuhei Nishiguchi, Naoya Sakamoto, Kiyoaki Ito, Masao Honda, Mina Nakagawa, Nobuyuki Enomoto, Nao Nishida, Masashi Mizokami, Hiroshi Yatsuhashi, Sei Kakinuma, Yasuhito Tanaka, Mamoru Watanabe
Publikováno v:
Hepatology Research. 40:1063-1071
Aim: Host genetic variants leading to inosine triphosphatase (ITPA) deficiency, a condition not thought to be clinically important, protect against hemolytic anemia in chronic hepatitis C patients receiving ribavirin. In this study, we evaluated the