Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Yuki Nakatsuji"'
Publikováno v:
Journal of Chromatography A. 1309:76-83
Monoclonal antibody (mAb) pharmaceuticals are much more complex than small-molecule drugs. Such complex characteristics raise challenging questions for regulatory evaluation. Although heterogeneity in mAbs based on their charge variants has been main
Autor:
Masahide Ohmichi, Masahiro Sakata, Seiji Mabuchi, Namiko Yada-Hashimoto, Jun Hayakawa, Yukihiro Nishio, Koji Hisamoto, Yuji Murata, Yuki Nakatsuji, Hozumi Seino-Noda, Keiichi Tasaka, Hiroshi Sasaki
Publikováno v:
Menopause (New York, N.Y.). 13(6)
Objective To investigate the effects of estradiol (E2) and raloxifene on the migration of human monocytic THP-1 cells to endothelium. Design A prospective comparative study. THP-1 cells, a human acute monocytic leukemia cell line, were used for the s
Autor:
Yuki Nakatsuji, Ken-ichirou Morishige, Masahide Ohmichi, Keiichi Tasaka, Kazushige Adachi, Nariaki Matsuura, Yukihiro Nishio, Hirohisa Kurachi, Naoyuki Tani, Yuji Murata, Koji Hisamoto
Publikováno v:
Endocrine journal. 50(6)
The trophoblast, an important component of the mammalian placenta, has several essential biological roles in the maintenance of pregnancy. First, trophoblast cells must attach to the uterine endometrium, and then they must invade to a depth at which
Autor:
Kimihiko, Ito, Susumu, Adachi, Takashi, Iijima, Yuki, Nakatsuji, Toshio, Kimura, Toshikatu, Nobunaga
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 30(1)
The established standard treatment for advanced ovarian cancer is carboplatin and paclitaxel. However, more than 70% of patients have recurrent disease. The standard therapy for recurrent ovarian cancer has not been confirmed. It was reported that do
Autor:
Jun Hayakawa, Seiji Mabuchi, Keiichi Tasaka, Emi Arimoto-Ishida, Yukihiro Nishio, Masahide Ohmichi, Kazuhiro Takahashi, Akiko Kimura, Kazushige Adachi, Koji Hisamoto, Yuji Murata, Yuki Nakatsuji
Publikováno v:
The Journal of biological chemistry. 277(36)
We studied the roles of the phosphatidylinositol 3-kinase (PI-3K)-Akt-BAD cascade, ERK-BAD cascade, and Akt-Raf-1 cascade in the paclitaxel-resistant SW626 human ovarian cancer cell line, which lacks functional p53. Treatment of SW626 cells with pacl