Zobrazeno 1 - 10
of 533
pro vyhledávání: '"Yuki NOGUCHI"'
Autor:
Masataka Kawamura, Catherine Parmentier, Samrat Ray, Sergi Clotet-Freixas, Sharon Leung, Rohan John, Laura Mazilescu, Emmanuel Nogueira, Yuki Noguchi, Toru Goto, Bhranavi Arulratnam, Sujani Ganesh, Tomas Tamang, Kaitlin Lees, Trevor W. Reichman, Ana C. Andreazza, Peter K. Kim, Ana Konvalinka, Markus Selzner, Lisa A. Robinson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract We previously reported that normothermic ex vivo kidney perfusion (NEVKP) is superior in terms of organ protection compared to static cold storage (SCS), which is still the standard method of organ preservation, but the mechanisms are incomp
Externí odkaz:
https://doaj.org/article/fde2c23c7d5e46e7ac674eec4e0b9a26
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Cells establish the asymmetrical distribution of phospholipids and alter their distribution by phospholipid scrambling (PLS) to adapt to environmental changes. Here, we demonstrate that a protein complex, consisting of the ion channel Tmem63
Externí odkaz:
https://doaj.org/article/606958fa799a451d800acfec7212ecdf
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103306- (2024)
Summary: In vivo genome-wide screening elucidates tissue-specific molecular events. Here, we present a protocol for an in vivo genome-wide CRISPR-Cas9 single-guide RNA (sgRNA) library screening technique optimized for mouse testicular cells to invest
Externí odkaz:
https://doaj.org/article/07d57468832b4fcd91f1829d151a54e7
Autor:
Hiroki Irie, Rei Suzuki, Yoshinori Okubo, Hiroyuki Asama, Naoki Konno, Yuki Noguchi, Ko Watanabe, Goro Shibukawa, Hidemichi Imamura, Tadayuki Takagi, Mitsuru Sugimoto, Yuki Sato, Jun Nakamura, Tsunetaka Kato, Minami Hashimoto, Takumi Yanagita, Takuto Hikichi, Hiromasa Ohira
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-6 (2023)
Abstract Purpose Drug-induced interstitial lung disease (ILD) is not a rare adverse event in the current chemotherapy strategy for pancreatic ductal adenocarcinoma (PDAC). Thus, we aimed to find the optimal management for PDAC patients with a history
Externí odkaz:
https://doaj.org/article/25e08f675d644c79b1ba2e72044a12c2
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-7 (2022)
Abstract We report that a locally resonant sonic material realizes omnidirectional acoustic invisibility in air. To achieve acoustic cloaking in the low-frequency regime, we axisymmetrically placed elastic rods comprised of silicone rubber and lead a
Externí odkaz:
https://doaj.org/article/c07976299e484ee3b7c567f740bbd80a
Autor:
Yuji Hori, Ken Ohmine, Hitoshi Katada, Yuki Noguchi, Kazuki Sato, Takeru Nambu, Lam Runyi Adeline, Gan Siok Wan, Kenta Haraya, Kazuhisa Ozeki, Masahiko Nanami, Tatsuhiko Tachibana, Zenjiro Sampei, Taichi Kuramochi, Junichi Nezu, Kunihiro Hattori, Tomoyuki Igawa
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
A conventional antibody targeting a soluble antigen in circulation typically requires a huge dosage and frequent intravenous administration to neutralize the antigen. This is because antigen degradation is reduced by the formation of antigen–antibo
Externí odkaz:
https://doaj.org/article/664a7d33da584019aead7576585d2286
Autor:
Peter Urbanellis, Laura Mazilescu, Dagmar Kollmann, Ivan Linares-Cervantes, J. Moritz Kaths, Sujani Ganesh, Fabiola Oquendo, Manraj Sharma, Toru Goto, Yuki Noguchi, Rohan John, Ana Konvalinka, Istvan Mucsi, Anand Ghanekar, Darius Bagli, Lisa A. Robinson, Markus Selzner
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Kidney transplantation with grafts procured after donation-after-cardiac death (DCD) has led to an increase in incidence of delayed graft function (DGF). It is thought that the warm ischemic (WI) insult encountered during DCD procurement is
Externí odkaz:
https://doaj.org/article/a7173aed0e084c24a0ec74188dd02156
Publikováno v:
Materials & Design, Vol 219, Iss , Pp 110832- (2022)
We present a topology optimization method for the design of labyrinthine metamaterials with a large path length for acoustic wave propagation. An objective function maximizes the pressure gradient in an air-filled region at a low frequency, and a lev
Externí odkaz:
https://doaj.org/article/7b68daf7711b4ec086622c699dbb9cd5
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Evaluation of the binding and uptake of an antibody in liver non-parenchymal cells (NPC), including liver sinusoidal endothelial cells, is important for revealing its pharmacokinetic (PK) behavior, since NPC has important roles in eliminatin
Externí odkaz:
https://doaj.org/article/1707556cd31c43a4a60f3a8bae3edeac
Autor:
Laura I. Mazilescu, MD, Peter Urbanellis, MD, MSc, Moritz J. Kaths, MD, MSc, Sujani Ganesh, MSc, Toru Goto, MD, Yuki Noguchi, MD, PhD, Rohan John, MD, Ana Konvalinka, MD, PhD, Istvan Mucsi, MD, PhD, Anand Ghanekar, MD, PhD, Darius J. Bagli, MD, MSc, Julie Turgeon, PhD, Annie Karakeusian Rimbaud, BSc, Marie-Josée Hébert, MD, Mélanie Dieudé, PhD, Isabelle Alleys, PhD, Etienne Dore, MSc, Eric Boilard, PhD, Herman S. Overkleeft, PhD, Lianne I. Willems, PhD, Lisa A. Robinson, MD, Markus Selzner, MD
Publikováno v:
Transplantation Direct, Vol 7, Iss 10, p e751 (2021)
Background. The increased usage of marginal grafts has triggered interest in perfused kidney preservation to minimize graft injury. We used a donation after circulatory death (DCD) porcine kidney autotransplantation model to compare 3 of the most fre
Externí odkaz:
https://doaj.org/article/af252ed324fa4c4ba755708e4549c1cb