Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Yuki Mochida"'
Autor:
Bo Zhang, Kenoki Ohuchida, Chikanori Tsutsumi, Yuki Shimada, Yuki Mochida, Koki Oyama, Chika Iwamoto, Nan Sheng, Shuang Fei, Koji Shindo, Naoki Ikenaga, Kohei Nakata, Yoshinao Oda, Masafumi Nakamura
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-21 (2024)
Abstract Background Pancreatic ductal adenocarcinoma tumors exhibit resistance to chemotherapy, targeted therapies, and even immunotherapy. Dendritic cells use glucose to support their effector functions and play a key role in anti-tumor immunity by
Externí odkaz:
https://doaj.org/article/b20edb6fb85846d38d40346792ae1511
Autor:
Yuki Mochida, Satoshi Uchida
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 1-27 (2024)
ABSTRACTAdjuvanticity and delivery are crucial facets of mRNA vaccine design. In modern mRNA vaccines, adjuvant functions are integrated into mRNA vaccine nanoparticles, allowing the co-delivery of antigen mRNA and adjuvants in a unified, all-in-one
Externí odkaz:
https://doaj.org/article/484502ec6d7f4372b2fd86b2d8fd6a78
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract We aimed to investigate the relationship between the risk of oral frailty and awareness of oral frailty among Japanese adults in an adult dental health field study conducted in Kanagawa Prefecture. Questionnaire data from a total of 5051 ind
Externí odkaz:
https://doaj.org/article/0a412e1c61f649c1822dc7b73b581fa9
Autor:
Miki Suzuki, Yuki Mochida, Mao Hori, Akimasa Hayashi, Kazuko Toh, Theofilus A. Tockary, Xueying Liu, Victor Marx, Hidetomo Yokoo, Kanjiro Miyata, Makoto Oba, Satoshi Uchida
Publikováno v:
Small Science, Vol 4, Iss 4, Pp n/a-n/a (2024)
Organ‐selective targeting of mRNA polyplexes has been rarely explored despite the substantial potential of polymer‐based systems in mRNA delivery. In this study, spleen‐selective delivery of polyplexes is achieved by employing mRNA engineering
Externí odkaz:
https://doaj.org/article/fe7bde1132c74192b0fb44db21d9b503
Autor:
Yuki Mochida, Ryohei Nishizawa, Koji Ochiai, Yoshitaka Inoue, Yasuhiko Kaita, Yoshihiro Yamaguchi
Publikováno v:
Surgical Case Reports, Vol 8, Iss 1, Pp 1-4 (2022)
Abstract Background Traumatic tension gastrothorax is a rare and potentially fatal condition occurring in patients with congenital or acquired diaphragmatic defects. Traumatic tension gastrothorax leads to acute and severe respiratory distress. Delay
Externí odkaz:
https://doaj.org/article/efb94dacd5e643b9bde8d5e402413cf2
Autor:
Sho Okuda, Kenoki Ohuchida, Shoichi Nakamura, Chikanori Tsutsumi, Kyoko Hisano, Yuki Mochida, Jun Kawata, Yoshiki Ohtsubo, Tomohiko Shinkawa, Chika Iwamoto, Nobuhiro Torata, Yusuke Mizuuchi, Koji Shindo, Taiki Moriyama, Kohei Nakata, Takehiro Torisu, Takashi Morisaki, Takanari Kitazono, Yoshinao Oda, Masafumi Nakamura
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106480- (2023)
Summary: Although chemotherapy has been an essential treatment for cancer, the development of immune checkpoint blockade therapy was revolutionary, and a comprehensive understanding of the immunological tumor microenvironment (TME) has become crucial
Externí odkaz:
https://doaj.org/article/a31b166674cc471891eaf4bb6406e9ce
Autor:
Tomohiko Shinkawa, Kenoki Ohuchida, Yuki Mochida, Kukiko Sakihama, Chika Iwamoto, Toshiya Abe, Noboru Ideno, Yusuke Mizuuchi, Koji Shindo, Naoki Ikenaga, Taiki Moriyama, Kohei Nakata, Yoshinao Oda, Masafumi Nakamura
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-20 (2022)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is characterized by abundant stroma in which microenvironmental (niche) factors promote PDAC progression. In mouse models, reduction of the stroma increased the proportion of poorly differen
Externí odkaz:
https://doaj.org/article/652265133c844549b4a8dda84189b7d1
Autor:
Yuki Mochida, Koji Ochiai, Takashi Nagase, Keiko Nonomura, Yoshihiro Akimoto, Hiroshi Fukuhara, Tatsuo Sakai, George Matsumura, Yoshihiro Yamaguchi, Miki Nagase
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract The kidney plays a central role in body fluid homeostasis. Cells in the glomeruli and juxtaglomerular apparatus sense mechanical forces and modulate glomerular filtration and renin release. However, details of mechanosensory systems in these
Externí odkaz:
https://doaj.org/article/765dc051d6f6474198065a1253487af7
Autor:
Shoichi Nakamura, Kenoki Ohuchida, Yoshiki Ohtsubo, Yutaka Yamada, Chikanori Tsutsumi, Sho Okuda, Kyoko Hisano, Yuki Mochida, Tomohiko Shinkawa, Chika Iwamoto, Nobuhiro Torata, Yusuke Mizuuchi, Koji Shindo, Kohei Nakata, Taiki Moriyama, Takehiro Torisu, Eishi Nagai, Takashi Morisaki, Takanari Kitazono, Yoshinao Oda, Masafumi Nakamura
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 1, Pp n/a-n/a (2023)
Abstract Background Tumour immune microenvironment is related with carcinogenesis and efficacy of immunotherapy. B cells play major roles in humoral immunity, but detailed functions of tumour‐infiltrating B lymphocytes (TIL‐Bs) are unknown. There
Externí odkaz:
https://doaj.org/article/2eb5651f2fdf491390cb52bc3aa6a53b
Autor:
Tatsuo Yamamoto, Michio Tanaka, Nobuichi Kuribayashi, Fuminobu Okuguchi, Haruhiko Isotani, Masahiro Iwamoto, Hidekatsu Sugimoto, Osamu Nakagawa, Masato Minabe, Shinya Fuchida, Yuki Mochida, Hiroki Yokoyama
Publikováno v:
Clinical and Experimental Dental Research, Vol 7, Iss 4, Pp 419-428 (2021)
Abstract Objectives Cardiovascular disease remains the most common cause of death in patients with type 2 diabetes mellitus. Because periodontitis is a risk factor of cardiovascular disease, identification of risk factors of periodontitis is valuable
Externí odkaz:
https://doaj.org/article/767e5aff829146b592384c79d584280d