Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Yuki Kuramoto"'
Autor:
Hironori Yamamoto, Yohei Miyashita, Hitoshi Minamiguchi, Kazuyoshi Hosomichi, Shohei Yoshida, Hidetaka Kioka, Haruki Shinomiya, Haruno Nagata, Kenji Onoue, Masato Kawasaki, Yuki Kuramoto, Akihiro Nomura, Yuichiro Toma, Tetsuya Watanabe, Takahisa Yamada, Yasuki Ishihara, Miho Nagata, Hisakazu Kato, Hideyuki Hakui, Yoshihiko Saito, Yoshihiro Asano, Yasushi Sakata
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Cardiac sarcoidosis (CS) is the scarring of heart muscles by autoimmunity, leading to heart abnormalities and patients with sarcoidosis with cardiac involvements have poor prognoses. Due to the small number of patients, it is difficult to st
Externí odkaz:
https://doaj.org/article/bad5efcab01a4fec982fe5fa0b2c6799
Autor:
Hideki Yasutake, Jong-Kook Lee, Akihito Hashimoto, Kiyoshi Masuyama, Jun Li, Yuki Kuramoto, Shuichiro Higo, Shungo Hikoso, Kyoko Hidaka, Atsuhiko T. Naito, Shigeru Miyagawa, Yoshiki Sawa, Issei Komuro, Yasushi Sakata
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Duchenne muscular dystrophy (DMD) is characterized by progressive muscle degeneration accompanied by dilated cardiomyopathy. Recently, abnormality of yes-associated protein (YAP) has been reported as the pathogenesis of muscle degeneration o
Externí odkaz:
https://doaj.org/article/9bdcceb878174d0dad5ab80684f07298
Autor:
Jun Li, Jong-Kook Lee, Keiko Miwa, Yuki Kuramoto, Kiyoshi Masuyama, Hideki Yasutake, Satoki Tomoyama, Hiroyuki Nakanishi, Yasushi Sakata
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Human induced pluripotent stem (hiPS) cells have been used as a cell source for regenerative therapy and disease modeling. The purity of hiPS-cardiomyocytes (hiPS-CMs) has markedly improved with advancements in cell culture and differentiation protoc
Externí odkaz:
https://doaj.org/article/81695f21c06f4e7aa368442839d059d2
Autor:
Tomoaki Higo, Atsuhiko T. Naito, Tomokazu Sumida, Masato Shibamoto, Katsuki Okada, Seitaro Nomura, Akito Nakagawa, Toshihiro Yamaguchi, Taku Sakai, Akihito Hashimoto, Yuki Kuramoto, Masamichi Ito, Shungo Hikoso, Hiroshi Akazawa, Jong-Kook Lee, Ichiro Shiojima, Peter J. McKinnon, Yasushi Sakata, Issei Komuro
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
DNA damage response (DDR) is activated in cardiomyocytes of the failing heart, but the type of DNA damage leading to DDR is unclear. Higoet al. show that in mice heart failure is caused in part by unrepaired DNA single-strand breaks in cardiomyocytes
Externí odkaz:
https://doaj.org/article/f167f426b5044f03bde4b9f896135c5c
Autor:
Susumu Naito, Shuichiro Higo, Satoshi Kameda, Shou Ogawa, Tomoka Tabata, Yasuhiro Akazawa, Daisuke Nakamura, Kei Nakamoto, Fusako Sera, Yuki Kuramoto, Yoshihiro Asano, Shungo Hikoso, Shigeru Miyagawa, Yasushi Sakata
Publikováno v:
Internal Medicine; 2023, Vol. 62 Issue 21, p3167-3173, 7p
Autor:
Tatsuro Hitsumoto, Osamu Tsukamoto, Ken Matsuoka, Junjun Li, Li Liu, Yuki Kuramoto, Shuichiro Higo, Shou Ogawa, Noboru Fujino, Shohei Yoshida, Hidetaka Kioka, Hisakazu Kato, Hideyuki Hakui, Yuki Saito, Chisato Okamoto, Hijiri Inoue, Jo Hyejin, Kyoko Ueda, Takatsugu Segawa, Shunsuke Nishimura, Yoshihiro Asano, Hiroshi Asanuma, Akiyoshi Tani, Riyo Imamura, Shinsuke Komagawa, Toshio Kanai, Masayuki Takamura, Yasushi Sakata, Masafumi Kitakaze, Jun-ichi Haruta, Seiji Takashima
Publikováno v:
Circulation.
Background: Cardiac-specific myosin light chain kinase (cMLCK), encoded by MYLK3 , regulates cardiac contractility through phosphorylation of ventricular myosin regulatory light chain. However, the pathophysiological and therapeutic implications of c
Autor:
Satoshi Kameda, Shuichiro Higo, Mikio Shiba, Takumi Kondo, Junjun Li, Li Liu, Tomoka Tabata, Hiroyuki Inoue, Shota Okuno, Shou Ogawa, Yuki Kuramoto, Hideki Yasutake, Jong-Kook Lee, Seiji Takashima, Yoshihiko Ikeda, Shungo Hikoso, Shigeru Miyagawa, Yasushi Sakata
Publikováno v:
JACC: Basic to Translational Science.
Autor:
Takumi Kondo, Shuichiro Higo, Mikio Shiba, Yasuaki Kohama, Satoshi Kameda, Tomoka Tabata, Hiroyuki Inoue, Shota Okuno, Shou Ogawa, Satoki Nakamura, Maki Takeda, Emiko Ito, Junjun Li, Li Liu, Yuki Kuramoto, Jong-Kook Lee, Seiji Takashima, Shigeru Miyagawa, Yoshiki Sawa, Shungo Hikoso, Yasushi Sakata
Publikováno v:
Circulation: Genomic and Precision Medicine. 15
Background: The Δ160E mutation in TNNT2 , which encodes troponin T, is a rare pathogenic variant identified in patients with hypertrophic cardiomyopathy and is associated with poor prognosis. Thus, a convenient human model recapitulating the patholo
Autor:
Hideyuki, Hakui, Hidetaka, Kioka, Fusako, Sera, Kei, Nakamoto, Kentaro, Ozu, Yuki, Kuramoto, Yohei, Miyashita, Tomohito, Ohtani, Shungo, Hikoso, Yoshihiro, Asano, Yasushi, Sakata
Publikováno v:
Circulation journal : official journal of the Japanese Circulation Society. 86(12)
Autor:
Shungo Hikoso, Kiyoshi Masuyama, Jun Li, Yuki Kuramoto, Shuichiro Higo, Shigeru Miyagawa, Akihito Hashimoto, Issei Komuro, Yoshiki Sawa, Atsuhiko T. Naito, Yasushi Sakata, Hideki Yasutake, Jong-Kook Lee, Kyoko Hidaka
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Scientific Reports
Duchenne muscular dystrophy (DMD) is characterized by progressive muscle degeneration accompanied by dilated cardiomyopathy. Recently, abnormality of yes-associated protein (YAP) has been reported as the pathogenesis of muscle degeneration of DMD; ho