Fracture Strength Evaluation of Agglomerates of Fatty Acid-Coated CaCO3 Nanoparticles by Nano-Indentation

Autor: Yuki Kezuka, Masahiko Tajika

Publikováno v: ChemEngineering, Vol 3, Iss 3, p 73 (2019)

Nanoparticles often form agglomerates during their manufacturing process. When nanoparticles form agglomerates, their inherent properties cannot be fully exploited. In this study, we attempted to establish a conventional method to evaluate the fractu

Externí odkaz: https://doaj.org/article/20a8975f8f9b40da8b80d58195d7e6b1

A systematic assessment of the impact of rare canonical splice site variants on splicing using functional and in silico methods.

Autor: Oh RY; Division of Clinical and Metabolic Genetics, Hospital for Sick Children, Toronto, ON, Canada; Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., AlMail A; Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada; Program in Genetics and Genome Biology, SickKids Research Institute, Toronto, ON, Canada., Cheerie D; Program in Genetics and Genome Biology, SickKids Research Institute, Toronto, ON, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada., Guirguis G; Program in Genetics and Genome Biology, SickKids Research Institute, Toronto, ON, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada., Hou H; Program in Genetics and Genome Biology, SickKids Research Institute, Toronto, ON, Canada., Yuki KE; Program in Genetics and Genome Biology, SickKids Research Institute, Toronto, ON, Canada; Division of Genome Diagnostics, Hospital for Sick Children, Toronto, ON, Canada., Haque B; Program in Genetics and Genome Biology, SickKids Research Institute, Toronto, ON, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada., Thiruvahindrapuram B; The Centre for Applied Genomics, SickKids Research Institute, Toronto, ON, Canada., Marshall CR; Division of Genome Diagnostics, Hospital for Sick Children, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Mendoza-Londono R; Division of Clinical and Metabolic Genetics, Hospital for Sick Children, Toronto, ON, Canada; Program in Genetics and Genome Biology, SickKids Research Institute, Toronto, ON, Canada; Department of Paediatrics, University of Toronto, Toronto, ON, Canada., Shlien A; Program in Genetics and Genome Biology, SickKids Research Institute, Toronto, ON, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada; Division of Genome Diagnostics, Hospital for Sick Children, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Kyriakopoulou LG; Division of Genome Diagnostics, Hospital for Sick Children, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Walker S; The Centre for Applied Genomics, SickKids Research Institute, Toronto, ON, Canada., Dowling JJ; Program in Genetics and Genome Biology, SickKids Research Institute, Toronto, ON, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada; Department of Paediatrics, University of Toronto, Toronto, ON, Canada; Division of Neurology, Hospital for Sick Children, Toronto, ON, Canada., Wilson MD; Program in Genetics and Genome Biology, SickKids Research Institute, Toronto, ON, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada., Costain G; Division of Clinical and Metabolic Genetics, Hospital for Sick Children, Toronto, ON, Canada; Program in Genetics and Genome Biology, SickKids Research Institute, Toronto, ON, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada; Department of Paediatrics, University of Toronto, Toronto, ON, Canada. Electronic address: gregory.costain@sickkids.ca.

Publikováno v: HGG advances [HGG Adv] 2024 Jul 18; Vol. 5 (3), pp. 100299. Date of Electronic Publication: 2024 Apr 24.

Synchronous T-lymphoblastic lymphoma and neuroblastoma in a 3-yr-old with novel germline SMARCA4 and EZH2 variants.

Autor: Tibout P; Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Ontario M5G 1E8, Canada., Livingston J; Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Ontario M5G 1E8, Canada., Kanwar N; Department of Pediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, Ontario M5G 1E8, Canada., Yuki KE; Department of Pediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, Ontario M5G 1E8, Canada., Shlien A; Department of Pediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, Ontario M5G 1E8, Canada.; Genetics and Genome Biology, The Hospital for Sick Children Research Institute, Toronto, Ontario, M5G 1E8 Canada., Ngan B; Division of Pathology, Department of Pediatric Laboratory Medicine, Hospital for Sick Children, Toronto, Ontario M5G 1E8, Canada., Irwin MS; Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Ontario M5G 1E8, Canada.; Department of Pediatrics, University of Toronto, Toronto, Ontario M5R 0A3, Canada., Morgenstern DA; Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Ontario M5G 1E8, Canada.; Department of Pediatrics, University of Toronto, Toronto, Ontario M5R 0A3, Canada., Hitzler J; Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Ontario M5G 1E8, Canada.; Department of Pediatrics, University of Toronto, Toronto, Ontario M5R 0A3, Canada., Villani A; Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Ontario M5G 1E8, Canada.; Department of Pediatrics, University of Toronto, Toronto, Ontario M5R 0A3, Canada., Cohen-Gogo S; Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Ontario M5G 1E8, Canada; sarah.cohen-gogo@sickkids.ca.; Genetics and Genome Biology, The Hospital for Sick Children Research Institute, Toronto, Ontario, M5G 1E8 Canada.

Publikováno v: Cold Spring Harbor molecular case studies [Cold Spring Harb Mol Case Stud] 2024 Jan 10; Vol. 9 (4). Date of Electronic Publication: 2024 Jan 10 (Print Publication: 2023).

Trio RNA sequencing in a cohort of medically complex children.

Autor: Deshwar AR; Division of Clinical and Metabolic Genetics, The Hospital for Sick Children, Toronto, ON, Canada; Program in Genetics and Genome Biology, SickKids Research Institute, Toronto, ON, Canada., Yuki KE; Program in Genetics and Genome Biology, SickKids Research Institute, Toronto, ON, Canada., Hou H; Program in Genetics and Genome Biology, SickKids Research Institute, Toronto, ON, Canada., Liang Y; Centre for Computational Medicine, The Hospital for Sick Children, Toronto, ON, Canada., Khan T; Program in Genetics and Genome Biology, SickKids Research Institute, Toronto, ON, Canada., Celik A; Centre for Computational Medicine, The Hospital for Sick Children, Toronto, ON, Canada., Ramani A; Centre for Computational Medicine, The Hospital for Sick Children, Toronto, ON, Canada., Mendoza-Londono R; Division of Clinical and Metabolic Genetics, The Hospital for Sick Children, Toronto, ON, Canada; Department of Paediatrics, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Marshall CR; Division of Genome Diagnostics, The Hospital for Sick Children, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Brudno M; Techna Institute for the Advancement of Technology for Health, University Health Network, Toronto, ON, Canada., Shlien A; Program in Genetics and Genome Biology, SickKids Research Institute, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Meyn MS; Center for Human Genomics and Precision Medicine, University of Wisconsin, Madison, WI, USA; Department of Pediatrics, University of Wisconsin, Madison, WI, USA., Hayeems RZ; Child Health Evaluative Sciences, SickKids Research Institute, Toronto, ON, Canada., McKinlay BJ; Department of Kinesiology, Faculty of Applied Health Sciences, Brock University, St. Catharines, ON, Canada., Klentrou P; Department of Kinesiology, Faculty of Applied Health Sciences, Brock University, St. Catharines, ON, Canada., Wilson MD; Program in Genetics and Genome Biology, SickKids Research Institute, Toronto, ON, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada., Kyriakopoulou L; Division of Genome Diagnostics, The Hospital for Sick Children, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Costain G; Division of Clinical and Metabolic Genetics, The Hospital for Sick Children, Toronto, ON, Canada; Program in Genetics and Genome Biology, SickKids Research Institute, Toronto, ON, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada; Department of Paediatrics, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada. Electronic address: gregory.costain@sickkids.ca., Dowling JJ; Program in Genetics and Genome Biology, SickKids Research Institute, Toronto, ON, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada; Division of Neurology, The Hospital for Sick Children, Toronto, ON, Canada; Department of Paediatrics, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada. Electronic address: james.dowling@sickkids.ca.

Publikováno v: American journal of human genetics [Am J Hum Genet] 2023 May 04; Vol. 110 (5), pp. 895-900. Date of Electronic Publication: 2023 Mar 28.

Transcriptional buffering and 3'UTR lengthening are shaped during human neurodevelopment by shifts in mRNA stability and microRNA load.

Autor: Mufteev M; Developmental & Stem Cell Biology, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada., Rodrigues DC; Developmental & Stem Cell Biology, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada., Yuki KE; Genetics & Genome Biology, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada., Narula A; Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada.; Molecular Medicine, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada., Wei W; Developmental & Stem Cell Biology, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada., Piekna A; Developmental & Stem Cell Biology, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada., Liu J; Developmental & Stem Cell Biology, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada., Pasceri P; Developmental & Stem Cell Biology, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada., Rissland OS; Molecular Medicine, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada.; RNA Bioscience Initiative and Department of Biochemistry & Molecular Genetics, University of Colorado School of Medicine, Aurora, Colorado 80045, USA., Wilson MD; Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada.; Genetics & Genome Biology, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada., Ellis J; Developmental & Stem Cell Biology, Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Mar 01. Date of Electronic Publication: 2023 Mar 01.