Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Yuki Hirota-Tsuyada"'
Autor:
Hanna Jaaro-Peled, Sunil Kumar, Dalton Hughes, Akiko Sumitomo, Sun-Hong Kim, Sandra Zoubovsky, Yuki Hirota-Tsuyada, Diana Zala, Julie Bruyere, Brittany M. Katz, Beverly Huang, Rafael Flores, Soumya Narayan, Zhipeng Hou, Aris N. Economides, Takatoshi Hikida, William C. Wetsel, Karl Deisseroth, Susumu Mori, Nicholas J. Brandon, Motomasa Tanaka, Koko Ishizuka, Miles D. Houslay, Frédéric Saudou, Kafui Dzirasa, Akira Sawa, Toshifumi Tomoda
Publikováno v:
Molecular Psychiatry. 27:1805-1815
Sensorimotor information processing underlies normal cognitive and behavioral traits and has classically been evaluated through prepulse inhibition (PPI) of a startle reflex. PPI is a behavioral dimension deregulated in several neurological and psych
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c5361c7dcda2626d9b38677ea2d8ef
https://doi.org/10.1038/s41380-021-01389-3
https://doi.org/10.1038/s41380-021-01389-3
Autor:
Hyunjung Oh, Leon French, Yuki Hirota-Tsuyada, Hitoshi Miyachi, Toshifumi Tomoda, Akiko Sumitomo, Rammohan Shukla, Etienne Sibille
Publikováno v:
Neuropsychopharmacology
Reduced brain-derived neurotrophic factor (BDNF) and gamma-aminobutyric acid (GABA) neurotransmission co-occur in brain conditions (depression, schizophrenia and age-related disorders) and are associated with symptomatology. Rodent studies show they
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9f96f7057bc4c3040b937b58e20435f
https://europepmc.org/articles/PMC8674239/
https://europepmc.org/articles/PMC8674239/
Autor:
Brittany M. Katz, Motomasa Tanaka, Aris N. Economides, Akiko Sumitomo, Susumu Mori, Rafael Flores, Sandra Zoubovsky, Beverly Huang, Kafui Dzirasa, Frédéric Saudou, Akira Sawa, Karl Deisseroth, Julie Bruyère, Toshifumi Tomoda, Koko Ishizuka, William C. Wetsel, Takatoshi Hikida, Dalton Hughes, Soumya Narayan, Diana Zala, Miles D. Houslay, Sunil Kumar, Sun Hong Kim, Zhipeng Hou, Nicholas J. Brandon, Hanna Jaaro-Peled, Yuki Hirota-Tsuyada
Sensorimotor information processing that underlies normal cognitive and behavioral traits is dysregulated across a subset of neurological and psychiatric disorders. The cross-disease deficit in sensorimotor gating poses a unique opportunity to integr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c51fe3799e69d4dfec56dc8fab7bbf5
https://doi.org/10.1101/497446
https://doi.org/10.1101/497446
Autor:
Yuki Hirota-Tsuyada, Hyunjung Oh, Rammohan Shukla, Toshifumi Tomoda, Hitoshi Miyachi, Akiko Sumitomo, Leon French, Etienne Sibille
SummaryReduced BDNF and GABAergic inhibition co-occur in neuropsychiatric diseases, including major depression. Genetic rodent studies show a causal link, suggesting the presence of biological pathways that mediate this co-occurrence. Here we show th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ddc66cbb55d1a602f6dfc27e9f44e5d
Autor:
Qi Wang, Akira Sawa, Srinivasa Subramaniam, Carsten Korth, Hanna Jaaro-Peled, Minori Koga, Koko Ishizuka, Neelam Shahani, Atsushi Kamiya, Saurav Seshadri, Yuki Hirota-Tsuyada, Nicholas J. Brandon, Toshifumi Tomoda, Thomas W. Sedlak
Publikováno v:
Molecular psychiatry
We report the novel regulation of proteolytic processing of amyloid precursor protein (APP) by DISC1, a major risk factor for psychiatric illnesses, such as depression and schizophrenia. RNAi knockdown of DISC1 in mature primary cortical neurons led
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::323897634c3366e74d5ddd397e787eb3
https://doi.org/10.1038/mp.2014.100
https://doi.org/10.1038/mp.2014.100