Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Yuki Hazama"'
Autor:
Yuki Sakata, Ryoto Nabekura, Yuki Hazama, Miho Hanya, Takashi Nishiyama, Isao Kii, Takamitsu Hosoya
Publikováno v:
Organic letters.
A concise route for dibenzoazacyclooctynes (DIBACs) synthesis was developed based on Pictet-Spengler reaction and a novel cobalt decomplexation method established for dibenzo-fused cyclooctyne-cobalt complexes. The method allowed for the facile prepa
Publikováno v:
Molecules, Vol 20, Iss 6, Pp 10131-10140 (2015)
An alternative method for generating arynes from ortho-silylaryl triflates using cesium carbonate and 18-crown-6 is reported. The method was efficiently applied to a variety of reactions between several arynes and arynophiles. We also demonstrated th
Externí odkaz:
https://doaj.org/article/3d33106e9e31471cb410c54b358c9922
Publikováno v:
Chemical Communications. 57:2621-2624
An efficient method to synthesize diaryl sulfides with structural diversity is disclosed. Demethylative hydrothiolation of aryne intermediates generated from o-iodoaryl triflates with methylthio-substituted o-silylaryl triflates and further aryne rea
Autor:
Takamitsu Hosoya, Yuki Hazama, Suguru Yoshida, Yoshitake Nishiyama, Masakazu Kondo, Takeshi Matsushita, Sayuri Goto
Publikováno v:
Chemistry Letters. 48:1038-1041
The clickabilities of various alkenyl and alkyl azides in the strain-promoted cycloaddition with dibenzo-fused cyclooctynes were investigated. Although alkenyl azides generally exhibited lower clic...
Publikováno v:
Chemistry Letters. 48:742-745
A convenient method for preparing diverse o-iodoaryl triflates by the desilyliodination of o-silylaryl triflates has been developed. The treatment of o-silylaryl triflates with 1,3-diiodo-5,5-dimet...
Autor:
Yuki Hazama, Michiyo Nakahara, Shigeko Nishimura, Hiroshi Fujita, Hiroyuki Asaka, Miyuki Teratani
Publikováno v:
Japanese Journal of Transfusion and Cell Therapy. 65:611-614
Autor:
Rie Iimori, Satoshi Inouye, Yuki Hazama, Suguru Yoshida, Yuki Sakata, Mitsuhiro Nakamura, Takamitsu Hosoya, Yuiko Miura-Sahara
Publikováno v:
Biochemical and biophysical research communications. 526(2)
Pholasin is classified as a photoprotein and comprises apoPholasin (an apoprotein of pholasin) and an unknown prosthetic group as the light-emitting source. The luminescence reaction of pholasin is triggered by reactive oxygen species. Recombinant ap
Autor:
Michiyo Nakahara, Yuki Hazama, Hiroyuki Asaka, Shigeko Nishimura, Hiroshi Fujita, Miyuki Teratani
Publikováno v:
Transfusion. 58:2383-2387
Background Ammonia in the plasma usually does not pass through the blood-brain barrier (BBB). However, it can affect the brain as a neurotoxin in neonates with anemia of prematurity. Excess intake of ammonia should therefore be restricted in conditio
Publikováno v:
Organic Letters. 19:3899-3902
A facile synthetic method for unsymmetrical tertiary phosphine oxides is reported. Sequential treatment of phosphonodithioic acid S,S-di(p-tolyl) esters with two Grignard reagents enabled the stepwise introduction of different carbon substituents on
Autor:
Takeshi Matsushita, Yuki Hazama, Suguru Yoshida, Takamitsu Hosoya, Junko Tanaka, Yoshitake Nishiyama
Publikováno v:
Chemical communications (Cambridge, England). 54(96)
Introduction of an amino group at the para position of doubly sterically-hindered aryl azides significantly enhances the reactivity with cyclooctynes. The distortability of the azido group is synergistically enhanced by the para-electron-donating gro