Výsledky vyhledávání - "Yuki FUJIMICHI"

Akademický článek

Ionizing irradiation not only inactivates clonogenic potential in primary normal human diploid lens epithelial cells but also stimulates cell proliferation in a subset of this population.

Autor: Yuki Fujimichi, Nobuyuki Hamada

Publikováno v: PLoS ONE, Vol 9, Iss 5, p e98154 (2014)

Over the past century, ionizing radiation has been known to induce cataracts in the crystalline lens of the eye, but its mechanistic underpinnings remain incompletely understood. This study is the first to report the clonogenic survival of irradiated

Externí odkaz: https://doaj.org/article/7f72792f73414f89b554f8c5ca9ed1bb

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Effects of irradiation on cumulative mortality in mice: shifting toward a younger age of death

Autor: Yuki Fujimichi, Michiya Sasaki, Kazuo Yoshida, Toshiyasu Iwasaki

Publikováno v: Journal of Radiation Research. 64:412-419

Recently, the question of whether cancer risk is only accelerated but not increased by radiation exposure has been raised. To explore this matter, we analyzed whether the cumulative mortality of irradiated mice could be explained by x-axis (age) shif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5d9ecd0654d02b334588f01c013605b9
https://doi.org/10.1093/jrr/rrad006

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Calculation of an Indicator for Early Death Using Atomic Bomb Survivors’ Data

Autor: Michiya Sasaki, Yuki Fujimichi, Kazuo Yoshida, Toshiyasu Iwasaki

Publikováno v: Journal of Radiation Protection and Research. 47:22-29

Background: A comprehensive, traceable, and easy-to-understand radiation risk indicator is desired for radiological protection. The early-onset hypothesis could be used for this purpose.Materials and Methods: An indicator for early death (IED) was de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2e8ad91a4b82c04ab3f7b1dd726e6bc4
https://doi.org/10.14407/jrpr.2021.00108

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Impressions of JHPS Symposium (Fiscal Year 2021)

Autor: Kosuke MATSUBARA, Tomoya TSUJI, Atsushi ENOMOTO, Naoki NOMURA, Michiya SASAKI, Yuki FUJIMICHI

Publikováno v: Japanese Journal of Health Physics. 56:324-334

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c550b4b30c33c5107b812c30dd34e282
https://doi.org/10.5453/jhps.56.324

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Estimated Risks of Radiation-induced Solid Cancers from Various Exposure Conditions and the Effects of Age and Follow-up Period on These Risks

Autor: Michiya Sasaki, Kazuo Yoshida, Yuki Fujimichi, Toshiyasu Iwasaki

Publikováno v: Japanese Journal of Health Physics. 55:144-153

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9d497c3c3cd1c984336f9c7f0b521c9b
https://doi.org/10.5453/jhps.55.144

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An Efficient Intestinal Organoid System of Direct Sorting to Evaluate Stem Cell Competition in Vitro

Autor: Toshiyasu Iwasaki, Kensuke Otsuka, Yuki Fujimichi, Masanori Tomita

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports

Stem cell competition could shed light on the tissue-based quality control mechanism that prevents carcinogenesis. To quantitatively evaluate stem cell competition in vitro, we developed a two-color intestinal organoid forming system. First, we impro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce0015cf0896e5bbc4d0dc5747f66f6d
http://link.springer.com/article/10.1038/s41598-019-55824-1

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Ionizing radiation alters organoid forming potential and replenishment rate in a dose/dose-rate dependent manner

Autor: Yuki Fujimichi, Kensuke Otsuka, Masanori Tomita, Toshiyasu Iwasaki

Publikováno v: Journal of radiation research. 63(2)

Intestinal organoids are an in vitro cultured tissue model generated from intestinal stem cells, and they contain a mixture of epithelial cell types. We previously established an efficient ‘one cell/well’ sorting method, and defined organoid-form

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f5db5c402ad814b2511a3db048606d9
https://pubmed.ncbi.nlm.nih.gov/34977948

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Joint Meeting of Young Researchers in the Field of Radiation Protection and Radiation Biology

Autor: Kazuji Miwa, Junya Nakajima, Ryohei Yamada, Junya Ishikawa, Seiko Hirota, Yoichi Tsubota, Masaaki Sunaoshi, Yuki Fujimichi, Noriaki Kataoka

Publikováno v: Japanese Journal of Health Physics. 54:140-145

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ac939c17d67affd3c13475d6f7b0a75a
https://doi.org/10.5453/jhps.54.140

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The importance of stem cell competition for low-dose and low-dose-rate radiation effects

Autor: Yuki Fujimichi

Publikováno v: Journal of the Atomic Energy Society of Japan. 61:788-792

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7f3bacc39f36d51f71601d4427e05658
https://doi.org/10.3327/jaesjb.61.11_788

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Cellular responses and gene expression profiles of colonic Lgr5+ stem cells after low-dose/low-dose-rate radiation exposure

Autor: Keiji Suzuki, Kensuke Otsuka, Masanori Tomita, Toshiyasu Iwasaki, Yuki Fujimichi

Publikováno v: Journal of Radiation Research

We previously found that high-dose-rate radiation induced a replenishment of the colonic Lgr5+ stem cell pool, whereas low-dose-rate radiation did not. To identify key molecules that determine the dose-rate effects on this stem cell pool, we harveste

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0db313d790d5e8de339558f8a076b4d6
https://doi.org/10.1093/jrr/rrx078

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