Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Yuki, Otani"'
Autor:
Yuki Otani, Yunqi Zhao, Guanyu Wang, Richard Labotka, Mark Rogge, Neeraj Gupta, Majid Vakilynejad, Dean Bottino, Yusuke Tanigawara
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 12, Pp 2124-2136 (2024)
Abstract Multiple myeloma (MM) treatment guidelines recommend waiting for formal progression criteria (FPC) to be met before proceeding to the next line of therapy. As predicting progression may allow early switching to next‐line therapy while the
Externí odkaz:
https://doaj.org/article/862531faf736495183488735ded1aa0e
Publikováno v:
Autoimmunity, Vol 57, Iss 1 (2024)
Autoimmune diseases (AIDs) alter the placental immune environment leading to fetal loss. This study investigated the effects of AIDs on pregnancy and the placenta in AID-prone MRL/MpJ-Faslpr/lpr mice and wild-type MRL/MpJ, which were mated with male
Externí odkaz:
https://doaj.org/article/bd2e39e92703421a9b746592024cd615
Autor:
Narumi Takahashi, Osamu Ichii, Masaya Hiraishi, Takashi Namba, Yuki Otani, Teppei Nakamura, Yasuhiro Kon
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0302041 (2024)
Gestational diabetes mellitus (GDM) in human patients disrupts glucose metabolism post-pregnancy, affecting fetal development. Although obesity and genetic factors increase GDM risk, a lack of suitable models impedes a comprehensive understanding of
Externí odkaz:
https://doaj.org/article/1be36a5e6f6a4fdbb48601a29336efa9
Autor:
Yuka Katayama, Osamu Ichii, Teppei Nakamura, Keita Yanase, Masaya Hiraishi, Takashi Namba, Yuki Otani, Teppei Ikeda, Erika Tsuji, Natsuko Tsuzuki, Ken Kobayashi, Yasuhiro Kon, Takanori Nishimura
Publikováno v:
Animals, Vol 13, Iss 23, p 3700 (2023)
Foreign body reactions (FBRs) are inadvertently observed in invading or artificially embedded materials, triggering inflammation and subsequent fibrotic processes to occur in situ. Here, we assessed the spatiotemporal formation of connective tissue a
Externí odkaz:
https://doaj.org/article/ea386ac13ca24471919ddf2f046dc4c9
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 1, Pp 44-54 (2022)
Abstract The identification of influenza epidemics and assessment of the efficacy of vaccination against this infection are major challenges for the implementation of effective public health strategies, such as vaccination programs. In this study, we
Externí odkaz:
https://doaj.org/article/892b4a17d6c24d13be0764611e265de6
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 3, Pp 188-198 (2021)
Abstract Lenvatinib is a tyrosine kinase inhibitor of the vascular endothelial growth factor receptor used against nonoperative thyroid cancer; however, hypertension is a major dose‐limiting side effect. In this study, hypertension caused by lenvat
Externí odkaz:
https://doaj.org/article/85c1231cc5ff4549968c7727fb574bb3
Autor:
Md. Rashedul ISLAM, Osamu ICHII, Teppei NAKAMURA, Takao IRIE, Md. Abdul MASUM, Marina HOSOTANI, Yuki OTANI, Yaser Hosny Ali ELEWA, Yasuhiro KON
Publikováno v:
The Journal of Reproduction and Development, Vol 66, Iss 6, Pp 529-538 (2020)
Cotton rats (Sigmodon hispidus, CRs) are commonly used as animal models in biomedical research. However, the reproductive characteristics and ovarian development in the CRs has not been widely investigated. We have previously shown that female CRs, i
Externí odkaz:
https://doaj.org/article/997da366981443b9ad38fbbbcf5ca85f
Autor:
Kenichiro Sakaguchi, Kohei Kawano, Yuki Otani, Yojiro Yanagawa, Seiji Katagiri, Evelyn E. Telfer
Publikováno v:
Animals, Vol 13, Iss 7, p 1141 (2023)
The amino acid metabolism of bovine follicles during in vitro growth (IVG) was evaluated to identify potential indicators of health during culture. The bovine ovarian cortex was sliced, prepared as strips, and cultured for 6 days. Tissue samples were
Externí odkaz:
https://doaj.org/article/9ff77af433c44efc94d55b37194c96ad
Autor:
Hidefumi, Kasai, Kim Linda, Poppenberg, Valentina, Fermanelli, Yuki, Otani, Yusuke, Tanigawara
Publikováno v:
Therapeutic Drug Monitoring. 45:318-326
Neutropenia is a major dose-limiting toxicity of cancer chemotherapy. Semi-mechanistic mathematical models have been applied to describe the time course of neutrophil counts. The objectives of this study were to develop a mathematical model describin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a14e22a37191db96b1744633565b43a
https://doi.org/10.1097/ftd.0000000000001036
https://doi.org/10.1097/ftd.0000000000001036
Autor:
Md. Rashedul Islam, Osamu Ichii, Teppei Nakamura, Takao Irie, Md. Abdul Masum, Yuki Otani, Takashi Namba, Tsolmon Chuluunbaatar, Yaser Hosny Ali Elewa, Yasuhiro Kon
Publikováno v:
Frontiers in Physiology, Vol 11 (2021)
The reproductive characteristics and ovarian development in cotton rats (Sigmodon hispidus, CRs) are unclear, although CRs are commonly used as animal models in biomedical research. We previously reported that young (6–8 weeks) CRs showed multi-ooc
Externí odkaz:
https://doaj.org/article/45ce3be305a64fa18cc9bd319395e73f